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Sökning: WFRF:(Aljassim Fatma)

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1.
  • Aljassim, Fatma, et al. (författare)
  • A whisper from the silent lung zone.
  • 2009
  • Ingår i: Pediatric pulmonology. - : Wiley. - 1099-0496 .- 8755-6863. ; 44:8, s. 829-32
  • Tidskriftsartikel (refereegranskat)abstract
    • Multiple breath inert gas washout (MBW) is now regarded as "an insightful, sound, and useful tool to explore the lung and its response to injury in all of its compartments". We describe the important finding of pronounced intra-acinar airways response to indirect challenge testing, detected using MBW but missed by spirometry, in an adolescent with evidence of airway inflammation, and a background of severe respiratory syncytial virus (RSV) infection as an infant. These tests were performed as part of an 18-year follow up of a cohort with severe RSV infection (requiring hospitalization) in the first year of life, and has previously reported significantly higher rates of symptoms of allergic asthma and other features of atopic disease at 13 years in comparison to age matched controls. Small airway dysfunction and ventilation inhomogeneity have emerged as important features of early respiratory disease processes, and this case report provides further evidence supporting its important role in reactive airways disease.
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2.
  • Sigurs, Nele, et al. (författare)
  • Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life.
  • 2010
  • Ingår i: Thorax. - : BMJ. - 1468-3296 .- 0040-6376. ; 65:12, s. 1045-52
  • Tidskriftsartikel (refereegranskat)abstract
    • An increased prevalence of asthma/recurrent wheeze (RW), clinical allergy and allergic sensitisation up to age 13 years has previously been reported in subjects hospitalised with respiratory syncytial virus (RSV) bronchiolitis in their first year of life compared with matched controls. A study was undertaken to examine whether these features persist into early adulthood, to report longitudinal wheeze and allergy patterns, and to see how large and small airway function relates to RSV infection and asthma.
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