| 1. |
- af Klinteberg, Britt, et al.
(författare)
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Projective risk variables in early adolescence and subsequent disinhibitory psychopathology
- 2008
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Ingår i: International Journal of Law and Psychiatry. - : Elsevier BV. - 0160-2527 .- 1873-6386. ; 31:3, s. 210-218
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Tidskriftsartikel (refereegranskat)abstract
- The objective was to examine early adolescent projective risk indicators for the development of antisocial behaviour as related to adult personality traits, psychopathy, and violent behaviour over the life span. Assessment data included Rorschach (Rr) ratings (at age 11-14 years), personality inventories (EPQ-I and KSP scales), and a shortened Psychopathy Check List (PCL) (administered at age 32-40 years), obtained from a group of 199 male subjects; and smoking habits (at age 36-44 years) obtained from 125 of those subjects. Results, controlled for intelligence, indicated that the high and very high risk groups, as determined by level of total Rr risk scores, were (1) significantly higher on self-rated IVE Impulsiveness, the anxiety-related KSP Muscular Tension, and nonconformity traits, as compared to the low Rr risk group - the very high risk group also scoring significantly higher on the EPQ Psychoticism scale, related to aggressiveness and cruelty; (2) higher on clinically rated PCL total sum and factor scores; and (3) they were overrepresented among Ss with subsequent violent offence, and Ss with heavy smoking habits. The results are discussed in terms of the possible usefulness of psychodynamic oriented cognitive-emotional indicators in the search for underlying mechanisms in the development of disinhibitory psychopathology.
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| 2. |
- af Klinteberg, Britt, et al.
(författare)
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Serotonin, personality and smoking
- 2000
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Ingår i: INTERNATIONAL JOURNAL OF PSYCHOLOGY. - 0020-7594. ; 35:3-4, s. 22-22
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Konferensbidrag (refereegranskat)
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| 3. |
- af Klinteberg, Britt, et al.
(författare)
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Smoking habits – Associations with personality/behavior, platelet monoamine oxidase activity and plasma thyroid hormone levels
- 2017
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Ingår i: Personality and Individual Differences. - : Elsevier. - 0191-8869 .- 1873-3549. ; 118, s. 71-76
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Tidskriftsartikel (refereegranskat)abstract
- The objective was to outline results from our scientific studies on the associations among childhood behavior, adult personality, and biochemical factors in smoking habits. The studies consisted of: (1) follow-up of young criminals and controls, subdivided into risk for antisocial behavior groups, based on childhood rating levels of a projective test; and adult smoking habit groups; and (2) a large group of young adults examined on the same inventories. Personality in terms of KSP and EPQ-I scale scores, controlled for intelligence, indicated that the high and very high risk groups displayed significantly higher self-rated impulsiveness, anxiety, and nonconformity, as compared to the low risk group. Further, the very high risk group subjects, found to be overrepresented among subjects with heavy smoking habits, displayed lower mean platelet MAO-B activity and higher thyroid hormone levels than the low risk group. Thus, the higher the childhood risk for antisocial behavior, the clearer the adult personality pattern making subjects more disposed for smoking appeared; and the higher smoking habits, the stronger the relationships with biochemical measures. Results are discussed in terms of possible underlying mechanisms influencing personality and smoking habits.
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| 4. |
- Alm, Maria, 1956-
(författare)
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När kunskap ska styra : Om organisatoriska och professionella villkor för kunskapsstyrning inom missbruksvården
- 2015
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This thesis focuses on the changed governance of the public sector and what it can entail for professional work in substance abuse treatment. The point of departure is one of these new forms of governing, namely ‘knowledge governance’, which refers to a policy-driven process for promoting the use of evidence-based practice. The overall aim is to contribute to understanding and knowledge of the meaning and the conditions for knowledge governance in substance abuse treatment. The thesis studies how knowledge is interpreted by professionals and adapted to local practice in relation to organizational and professional conditions. The thesis also highlights the implications that these conditions may have for knowledge development on a professional and organizational level. The empirical material comprises three studies. Study 1 included a document analysis and a literature review. The document analysis examines how knowledge governance is described in official documents, while the focus of the literature review is on the concept of knowledge management. In Studies 2 and 3 focus group interviews were conducted with professionals who participated in a specific project, and professionals who use structured interview methods in their work (Addiction Severity Index, ASI, or Documentation of clients, DOC). The theoretical perspectives used in the thesis are neo-institutional theory, professional theory and perspectives on workplace learning. The results of Study 1 showed that knowledge governance embodies a steering of organizations, in comparison with knowledge management as a means for steering in organizations. The analyses from the focus group interviews demonstrate that knowledge governance becomes the subject of translations and edits to a local context. This process was affected by both organizational and professional conditions. The thesis is concluded with a discussion of the conditions that must be present if knowledge governance can lead to development of knowledge. The main result is that strategies must be tailored to each organization's specific condition and must be anchored throughout the organization.
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| 5. |
- Alm, Per Olof
(författare)
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Juvenile and adult criminality : relationships to platelet MAO activity, triiodothyronine, ADHD, conduct disorder and psychopathy
- 1996
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Indicators for persistent risk criminality in a group of grown up juvenile delinquents were investigated. The subjects had been examined In 'Young Lawbreakers': a study of 192 boys from an urban area, aged 11-14 years in 1959-1963. They had committed crime against property, serious enough for prosecution if not being underaged. The control group included 95 boys, matched for age, family type, social group and area of dwelling. As adults the original cohort was followed up sociologically and 199 of them also psychologically. Within a somatic-physiologic follow up, performed in 1989-91, the present study included 78 former juvenile delinquents and 47 controls (mean age 43.5 years) of the psychologically examined subjects. Biological variables, behaviour symptoms during adolescence and psychopathy related personality traits as adults were studied in relation to the subjects' cumulated registered criminality. The juvenile delinquents were classified into two groups: subjects registered for crime from 15 years of age and those who were not. Subjects from the control group, never registered for crime, were used as a normative group. All subjects were distributed into 'low' and 'high' groups according to the median platelet monoamine oxidase (MAO) activity and the mean of triiodothyronine (T3), of the control group, diagnosis of conduct disorder (CD) or not, and scores or not on the Psychopathy Check List (PCL). The presence of low platelet MAO activity increased the relative risk for persistent criminality more than three times. Of juvenile delinquents with low platelet MAO activity and PCL scores 70% persisted in crime in contrast to none of those with high platelet MAO activity and no PCL score. No correlation was found between platelet MAO activity and PCL scores. Increased levels of T3 were found to be associated with a more than three times increased risk for persistent criminality. The presence of symptoms of ADHD and CD were correlated to each other. CD was found to be the main contributor to persistent criminality. Risk indicators for persistent criminality were low platelet MAO activity. Presence of PCL scores, high level of T3 and a diagnosis of CD. Configuration Frequency Analysis revealed one significant 'type' constituted by a high number of risk indicators, 'early' debut in crime and persistent criminality, and another 'type' with no or a low number of risk indicators, 'late' debut in crime and no persistent criminality.
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| 6. |
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| 7. |
- Grann, Martin, et al.
(författare)
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Methodological development : structured outcome assessment and community risk monitoring (SORM)
- 2005
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Ingår i: International Journal of Law and Psychiatry. - : Elsevier BV. - 0160-2527 .- 1873-6386. ; 28:4, s. 442-456
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Tidskriftsartikel (refereegranskat)abstract
- This paper describes an effort to develop a clinical tool for the continuous monitoring of risk for violence in forensic mental health clients who have left their institutions and who are dwelling in the community on a conditional release basis. The model is called Structured Outcome Assessment and Community Risk Monitoring (SORM). The SORM consists of 30 dynamic factors and each factor in SORM is assessed in two ways: The current absence, presence or partial och intermittent presence of the factors, which is an actuarial (systematized and 'objective') assessment. Secondly, the risk effect, i.e. whether the presence/absence of factors currently increases, decreases or is perceived as unrelated to violence risk, is a clinical (or impressionistic) assessment. Thus, the factors considered via the SORM can be coded as risk factors or protective factors (or as factors unimportant to risk of violence) depending on circumstances that apply in the individual case. Further, the SORM has a built-in module for gathering idiographical information about risk-affecting contextual factors. The use of the SORM and its potential as a risk monitoring instrument is illustrated via preliminary data and case vignettes from an ongoing multicenter project. In this research project, patients leaving any of the 9 participating forensic hospitals in Sweden is assessed at release on a variety of static background factors, and the SORM is then administered every 30 days for 2 years.
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| 8. |
- Nilsson, Kent W., et al.
(författare)
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Role of monoamine oxidase A genotype and psychosocial factors in male adolescent criminal activity
- 2006
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Ingår i: Biological Psychiatry. - Uppsala Univ, Clin Res Ctr, Cent Hosp Vasteras, S-72189 Vasteras, Sweden. Uppsala Univ, Dept Neurosci, Pharmacol Unit, S-72189 Uppsala, Sweden. : Elsevier. - 0006-3223 .- 1873-2402. ; 59:2, s. 121-127
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: A number of important sociological, psychological, and biological predictors of adolescent criminal behavior have been identified during the most recent decades. The aim of this study was to replicate recent findings that interactions between a polymorphism in the monoamine oxidase A (MAO-A) gene promoter region and psychosocial factors might predict male adolescent criminal activity.METHODS: A cross-sectional study with a randomized sample from the total population of 16- and 19-year-olds from the county of Västmanland, Sweden. Eighty-one male adolescents, who volunteered to participate, were randomly selected from groups representing different degrees of deviant risk behavior.RESULTS: The present study strongly supports the notion that carrying the 3-repeat allele of the MAO-A-gene promoter increases the risk of male adolescent criminal behavior, when interacting with psychosocial factors. No effects at all of the MAO-A genotype on adolescent criminal activity were found when MAO-A genotype was considered alone (i.e., without its psychosocial context). The explained variance of the bio-psychosocial model (controlling for MAO-A) in this study exceeded the psychosocial model by 12%.CONCLUSIONS: The findings support the notion that genotype and psychosocial factors interact to precipitate male adolescent criminal behavior.
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| 9. |
- Nilsson, Kent W., et al.
(författare)
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Role of the serotonin transporter gene and family function in adolescent alcohol consumption.
- 2005
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Ingår i: Alcoholism. - Uppsala Univ, Clin Res Ctr, Cent Hosp Vasteras, S-72189 Vasteras, Sweden. Uppsala Univ, Dept Neurosci, Pharmacol Unit, S-72189 Vasteras, Sweden. : Wiley-Blackwell Publishing Inc.. - 0145-6008 .- 1530-0277. ; 29:4, s. 564-570
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: That the extent to which a particular individual will engage in problematic behaviors such as delinquency, violence, or drug abuse is determined by the way psychosocial, situational, and hereditary factors interact is widely accepted. However, only recently have researchers begun to investigate the interactions between specific genotypes and psychosocial factors in relation to behavior. The purpose of the present study was to investigate possible interactions between a polymorphism in the promoter region of the serotonin transporter (5-HTT) gene and family relations on adolescent alcohol consumption.METHODS: A cross-sectional study with a randomized sample from a total population of 16- and 19-year-old adolescents from a Swedish county was conducted. Eighty-one male and 119 female adolescents, who volunteered to participate after having answered a questionnaire, were randomly selected from quartiles of volunteers representing various degrees of psychosocial risk behavior.RESULTS: 5-HTT genotype (p=0.029) and family relations (p=0.022) predicted alcohol consumption independently as well as through an interaction with one another (p=0.05). The model explained 11% of the variance in alcohol consumption. In a binary logistic model, we found that adolescents with the LS variant of the 5-HTT gene and with family relations being "neutral" or "bad" had a 12- to 14-fold increased risk for high intoxication frequency.CONCLUSIONS: In sum, our results show that a functional polymorphism of the 5-HTT genotype, family relations, and interactions between these variables predict adolescent alcohol consumption in a randomized sample of adolescents.
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