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Sökning: WFRF:(Ambrosio Fabrisia)

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1.
  • Ambrosio, Fabrisia, et al. (författare)
  • Biological basis of exercise-based treatments for musculoskeletal conditions
  • 2011
  • Ingår i: PM&R. - : Elsevier. - 1934-1482 .- 1934-1563. ; 3:6 Suppl 1, s. S59-S63
  • Forskningsöversikt (refereegranskat)abstract
    • Exercise-based therapies are the cornerstone of rehabilitation programs. While the benefits of exercise on systemic and tissue function are generally accepted, mechanisms underlying these benefits are sometimes poorly understood. An improved understanding of the effects of mechanical loading on molecular and cellular processes has the potential to lead to more disease-specific and efficacious exercise-based therapies. The purpose of this paper is to review the current literature examining the role of mechanical signaling on muscle and cartilage biology.
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2.
  • Ambrosio, Fabrisia, et al. (författare)
  • The effect of muscle loading on skeletal muscle regenerative potential : an update of current research findings relating to aging and neuromuscular pathology
  • 2009
  • Ingår i: American Journal of Physical Medicine & Rehabilitation. - Baltimore : Lippincott Williams & Wilkins. - 0894-9115 .- 1537-7385. ; 88:2, s. 145-155
  • Forskningsöversikt (refereegranskat)abstract
    • Skeletal muscle is a dynamic tissue with a remarkable ability to continuously respond to environmental stimuli. Among its adaptive responses is the widely investigated ability of skeletal muscle to regenerate after loading or injury or both. Although significant basic science efforts have been dedicated to better understand the underlying mechanism controlling skeletal muscle regeneration, there has been relatively little impact in the clinical approaches used to treat skeletal muscle injuries and wasting. The purpose of this review article is to provide an overview of the basic biology of satellite cell function in response to muscle loading and to relate these findings in the context of aging and neuromuscular pathology for the rehabilitation medicine specialist.
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