| 1. |
- Ahlberg, Erik, et al.
(författare)
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"Vi klimatforskare stödjer Greta och skolungdomarna"
- 2019
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Ingår i: Dagens nyheter (DN debatt). - 1101-2447.
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- DN DEBATT 15/3. Sedan industrialiseringens början har vi använt omkring fyra femtedelar av den mängd fossilt kol som får förbrännas för att vi ska klara Parisavtalet. Vi har bara en femtedel kvar och det är bråttom att kraftigt reducera utsläppen. Det har Greta Thunberg och de strejkande ungdomarna förstått. Därför stödjer vi deras krav, skriver 270 klimatforskare.
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| 2. |
- Locke, Adam E, et al.
(författare)
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Genetic studies of body mass index yield new insights for obesity biology.
- 2015
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 518:7538, s. 197-401
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Tidskriftsartikel (refereegranskat)abstract
- Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P < 5 × 10(-8)), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ∼2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.
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| 3. |
- Shungin, Dmitry, et al.
(författare)
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New genetic loci link adipose and insulin biology to body fat distribution.
- 2015
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 518:7538, s. 187-378
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Tidskriftsartikel (refereegranskat)abstract
- Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms.
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| 4. |
- Anderson, Johan, 1973-, et al.
(författare)
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Assessment of Self-Heating in Wood Pellets by FE Modelling
- 2017
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Konferensbidrag (refereegranskat)abstract
- The self-heating process in a laboratory scale experiment has been modelled using the Comsol Multiphysics software. In the simulations the gas flow and air movement in the volume and heat diffusion in the bulk were taken into account however only one reaction in the pellets bulk is considered. The input data is found from measurements of the reaction chemistry and the heat transfer properties. It is found that all relevant physics is needed in order to obtain reasonable predictions in particular the heat transfer between the bulk and the gas is important but also condensation and evaporation of moisture.
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| 5. |
- Anderson, Johan, et al.
(författare)
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Experimental and Numerical Characterization of an Electrically Propelled Vehicles Battery Casing Including Battery Module
- 2014
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Ingår i: Journal of Thermal Science and Engineering Applications. - : ASME International. - 1948-5085 .- 1948-5093. ; 6:4
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Tidskriftsartikel (refereegranskat)abstract
- This paper demonstrates the possibility to predict a battery system's performance in a fire resistance test according to the new amendment of United Nations Regulation No. 100 "Uniform Provisions Concerning the Approval of Vehicles with Regard to Specific Requirements for the Electric Power Train" (R100) based on careful measurements of the physical properties of the casing material, as well as modeling of the battery modules and computer simulations. The methodology of the work consists of estimating the heat transfer coefficients by using a gasoline pool fire model in the computational fluid dynamics (CFD) software FIRE DYNAMICS SIMULATOR (FDS), followed by finite-element (FE) calculations of the temperatures in the battery.
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| 6. |
- Anderson, Johan, et al.
(författare)
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FDS SIMULATIONS AND MODELLING EFFORTS OF TRAVELLING FIRES IN A LARGE ELONGATED COMPARTMENT
- 2019
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Ingår i: Interflam 2019, proceedings. - : Interscience Communications. ; , s. 2085-
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Konferensbidrag (refereegranskat)abstract
- The present paper investigates a travelling fire scenario in an elongated structure (Length 18 m x width 6 m x height 3 m) with a controlled fire source of six pans filled with diesel (width 4 m x length 0.5 m). The fire spread is controlled manually by initiating fires subsequently in the pools. Fire Dynamics Simulator (FDS) is used to a-priori investigate variations in geometry, material data and fire load whereas simulations using the final design were performed after the test. The input to the model beside fire source and geometry are thermal material data. The FDS simulation were used to determine the appropriate size of the downstands (2 m from the ceiling in the final design) on the side to create a sufficiently one-dimensional fire spread. The post test simulations indicate that although there are a lot of variations not included in the model similar results were obtained as in the test.
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| 7. |
- Anderson, Johan, et al.
(författare)
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FDS simulations and modelling efforts of travelling fires in a large elongated compartment
- 2021
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Ingår i: Fire and Materials. - : John Wiley and Sons Ltd. - 0308-0501 .- 1099-1018. ; 45:6, s. 699-
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Tidskriftsartikel (refereegranskat)abstract
- The present paper investigates a travelling fire scenario in an elongated structure (Length 18 m × width 6 m × height 3 m) with a controlled fire source of six trays filled with diesel (width 4 m × length 0.5 m). The fire spread is controlled manually by initiating fires consecutively in the pools. Fire dynamics simulator (FDS) is used to a-priori investigate variations in geometry, material data and fire load, whereas simulations using the final design and measured heat release rates (HRR) were performed after the test. The input to the model beside fire source and geometry are thermal material data. The FDS simulations were used to determine the appropriate size of the downstands (2 m from the ceiling in the final design) on the side to create a sufficiently one-dimensional fire spread. The post-test simulations indicate that although there are a lot of variations not included in the model similar results were obtained as in the test.
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| 8. |
- Andrae, Anders, 1973, et al.
(författare)
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Uncertainty estimation by Monte Carlo Simulation applied to Life Cycle Inventory of Cordless Phones and Microscale Metallization Processes
- 2004
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Ingår i: IEEE Transactions on Electronics Packaging Manufacturing. ; 27:4, s. 233-245
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Tidskriftsartikel (refereegranskat)abstract
- This paper focuses on uncertainty analysis, that is, how the input data uncertainty affects the output data uncertainty in small but realistic product systems is modeled. The motivation for the study is to apply the Monte Carlo simulation for uncertainty estimation in life cycle inventory and environmental assessment of microelectronics applications. This paper addresses the question whether there is an environmental advantage of using DECT phones instead of GSM phones in offices. The paper also addresses the environmental compatibility of Electrochemical Pattern Replication (ECPR) compared to classical photolithography based microscale metallization (CL) for pattern transfer. Both environmental assessments in this paper consider electricity consumption and CO2 emissions. The projects undertaken are two comparative studies of DECT phone/GSM phone and ECPR/CL respectively. The research method used was probabilistic uncertainty modelling with a limited number of inventory parameters used in the MATLAB tool. For the DECT/GSM study the results reflects the longer DECT technical life which is an environmental advantage. For the Electrochemical Pattern Replication (ECPR)/classical photolithography based microscale metallization (CL) study the results reflects the fewer number of process steps and the lower electricity consumption needed by the ECPR to reach the functional unit. The difference in results is large enough to be able to draw conclusions, as the processes with the highest electricity consumption within the system boundaries have been determined. Based on earlier work a straightforward method to include uncertainty for input life cycle inventory data is used to quantify the influence of realistic errors for input data in two microelectronic applications. The conclusion is that the ECPR technology is more electricity efficient than CL in producing one layer of copper on a silicon wafer having a diameter of 20.32 cm. The conclusion is that the longer technical life of a cordless DECT phone is reflected in an electricity/CO2 comparison with a GSM phone, if use in an office is considered. Reasonable uncertainty intervals used for the input life cycle inventory data for the studied DECT/GSM and ECPR/CL system does affect the outcome of calculation of emission of CO2 but not to the degree that conclusions are not valid.Different uncertainty intervals and probability distributions could apply for different types of data and the interrelated input data dependence should be investigated. Today there exist very few life cycle inventory (LCI) data with the range of uncertainty for input and output elements. It must be emphasized that the upcoming LCI databases should have standard deviation characterized LCI data just as the Swiss ecoinvent LCI database.More inventory parameters and probability distributions characteristic for microsystems could be included and error analysis should be applied to future life inventory methodology, especially for future packaging concepts such as System-In-a-Package and System-On-a-Chip comparisons.
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