| 1. |
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Handbook of Creative Cities
- 2011
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Samlingsverk (redaktörskap) (refereegranskat)abstract
- With the publication of The Rise of the Creative Class by Richard Florida in 2002, the ‘creative city’ became the new hot topic among urban policymakers, planners and economists. Florida has developed one of three path-breaking theories about the relationship between creative individuals and urban environments. The economist Åke E. Andersson and the psychologist Dean Simonton are the other members of this ‘creative troika’. In the Handbook of Creative Cities, Florida, Andersson and Simonton appear in the same volume for the first time. The expert contributors in this timely Handbook extend their insights with a varied set of theoretical and empirical tools. The diversity of the contributions reflect the multidisciplinary nature of creative city theorizing, which encompasses urban economics, economic geography, social psychology, urban sociology, and urban planning. The stated policy implications are equally diverse, ranging from libertarian to social democratic visions of our shared creative and urban future.
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| 2. |
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| 3. |
- Abrahamsson, Victor, et al.
(författare)
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Method development in inverse modeling applied to supercritical fluid extraction of lipids
- 2016
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Ingår i: Journal of Supercritical Fluids. - : Elsevier BV. - 0896-8446. ; 111, s. 14-27
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Tidskriftsartikel (refereegranskat)abstract
- Modeling of the supercritical fluid extraction of solid materials is an important aspect in order to understand and predict the process. A comparison of two empirical models, two semi-empirical models and two mechanistic models is performed using calibration of single experiments. It is concluded that the best fit is obtained using a simple empirical expression. Furthermore, single calibrations did not generate reliable parameters with physical meaning and a methodology is proposed for inverse modeling with complete calibration using several experiments. The experimental dataset contained 29 extractions of lipids from crushed linseeds with varying temperatures, pressures and flow rates. A general rate model and a proposed extension of the hot ball model were evaluated for this purpose. The methodology includes data acquisition, model structure estimation, model calibration and a cross-validation. In general, it was found that the solubility model of Sovová outperformed the other evaluated correlations, and for the general rate model the Toth partition isotherm was also found in the top model structures. However, no generalization could be made regarding the correlations describing the Nernst diffusion layer and diffusivity.
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| 4. |
- Abrahamsson, Victor, et al.
(författare)
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Multicomponent inverse modeling of supercritical fluid extraction of carotenoids, chlorophyll A, ergosterol and lipids from microalgae
- 2018
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Ingår i: Journal of Supercritical Fluids. - : Elsevier BV. - 0896-8446. ; 139, s. 53-61
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Tidskriftsartikel (refereegranskat)abstract
- The fundamentals of analyte extractable fraction, solubility, partitioning and mass transfer resistance in supercritical fluid extraction were studied using inverse modeling. These phenomena are essential for understanding, predicting and optimizing the supercritical fluid extraction process. Carotenoids, chlorophyll A, ergosterol and total lipids were extracted from the microalgae Chlorella sp. The analytes were measured continuously in-line and on-line using UV/Vis absorption spectroscopy measurements and by evaporative light scattering detection. Various pressures, temperatures, flow rates and fractions of ethanol as a co-solvent were evaluated. The extractable fraction of carotenoids, chlorophyll A and total lipids were dependent on the co-solvent fraction in the extraction phase. The additional amount that could be extracted by using more co-solvent followed a normal distribution, indicating that analytes should not simply be categorized into weakly or strongly bound. The characteristics of diminishing extraction rates over time was accounted for by analyte partitioning rather than intra-particle diffusion limitations.
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| 5. |
- Andersson, Bengt-Åke
(författare)
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Circulating Biomarkers in Patients with Head and Neck Cancer and the Influence of Cigarette Smoking
- 2019
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Head and neck cancer (HNC) is a collective name for heterogeneous tumors located in the head and neck regions for which smoking, alcohol and human papillomavirus (HPV) are documented risk factors. The survival of HNC patients has only improved marginally during the last decade. The most important prognostic factors are tumor size, local spread and distant metastases, tumor node metastasis (TNM) staging. Prognostic biomarkers are needed as a complement to TNM staging.The aim for this thesis was to investigate rapid and low cost blood based biomarkers which could indicate the risk of HNC, recurrence of the disease or the survival of HNC patients. Furthermore, the aim was to examine how cigarette smoking influences the levels of biomarkers.In paper I, a possible role of plasma cytokines or proteins associated with immune response or inflammation, as biomarkers for the survival of HNC patients was investigated. Higher levels of C-reactive protein (CRP) and tumor necrosis factor alpha (TNF-α) were detected in plasma of the patients compared with the levels in the controls. The elevated levels of these two biomarkers detected in patients were associated with decreased survival.In paper II, the influence of 45 single nucleotide polymorphisms (SNPs) located in 41 genes associated with cell cycle progression, cell death, DNA repair or immune response on cancer risk, tumor recurrence and survival in HNC patients were investigated. SNPs in immune response genes were associated with risk for HNC, an elevated risk for recurrence and a decreased survival in HNC patients.In paper III, the influence of cigarette smoking on levels of inflammatory cells, proteins or cytokines/chemokines, microRNAs (miRNAs) and SNPs was analysed in healthy smokers and non-smokers. Higher levels of total white blood cells (WBCs), neutrophils, monocytes, lymphocytes, neutrophil to lymphocyte ratio (NLR), CRP, monocyte chemoattractant protein- 1 (MCP-1) and interferon gamma (IFN-γ) were detected in smokers compared to non-smokers and indicate an inflammatory response. Also, a lower level of oncomiRNA miR-21was detected in smokers. This alteration, in combination with the elevated levels of IFN-γ in smokers could be a protective response to cigarette smoke. The higher levels of IFN-γ in smokers compared to non-smokers were however only detected in individuals with SNP rs2069705 genotype AG/GG. This indicates a genetic association of the levels of IFN-γ.In paper IV, the separate effects of cigarette smoking and HNC on inflammatory or immune biomarkers and the impact of high risk human papillomavirus, age and gender were investigated. Comparisons of circulating levels of WBCs and its subpopulations, plasma proteins or cytokines/chemokines between smoking and non-smoking patients, smoking and non-smoking controls and between the patient and control groups were analysed. Smoking had highest impact on elevated levels of WBCs, IFN-γ and MCP-1, and HNC had highest impact on elevated levels of neutrophils, monocytes, NLR, CRP, macrophage inflammatory protein 1 beta and TNF-α.In conclusion, host immune response associated parameters could be suitable as biomarkers for the risk of HNC, risk of recurrence or in predicting survival of HNC patients. This thesis show that HNC are associated with systemic inflammatory response and upregulated CRP and TNF-α is related to shorter survival in HNC patients. Additionally, SNPs in immune response genes such as rs1800629 in the TNF-α gene indicates a risk for HNC or an elevated risk for recurrence and a decreased survival in HNC patients. These rapid and low cost blood based biomarkers could be used in combination or as a supplement to established biomarkers in the clinic for a more personalized treatment modality.
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| 6. |
- Andersson Bäck, Monica, 1969, et al.
(författare)
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Lofty ideals and lowly troubles among nursing home managers
- 2018
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Ingår i: The Management of Wicked Problems in Health and Social Care. - New York, NY : Routledge, 2019. | Series: Routledge studies in health management : Routledge. - 9781138103627 - 9781351592536 ; , s. 62-74
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Bokkapitel (refereegranskat)
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| 7. |
- Andersson, Charlotta, et al.
(författare)
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En modell som stöd för att utforska ekvationer : [A model to support exploring equations]
- 2022
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Ingår i: LUMAT. - 2323-7112. ; 10:1, s. 182-209
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Tidskriftsartikel (refereegranskat)abstract
- Syftet med artikeln är att lyfta fram om, och i sådant fall på vilka sätt, en specifik strukturell modell kan utgöra stöd när elever utforskar matematiska strukturer i ekvationer. Artikeln bygger på en empirisk forskningsstudie där elever utforskade matematiska strukturer med stöd av modellen, vilken är avsedd att visualisera strukturer. Lärare och forskare arbetade i en kollaborativ och intervenerande studie i iterativa processer. Sammantaget 149 elever från grundskolans årskurser 3, 8 och 9 deltog i filmade forskningslektioner utifrån forskningsansatsen learning study. Lektionerna designades med inspiration från ramverket lärandeverksamhet och eleverna utmanades i ett teoretiskt arbete. Analysen utfördes utifrån tematisk ansats och två kvalitativt skilda kärnteman identifierades: Formulär respektive Lärandemodell. I analysen framträdde att undervisningen behöver vara tillräckligt utmanande för att eleverna ska finna modellen meningsfull. Undervisningen behöver möjliggöra för eleverna att urskilja relationer mellan alla tal i en ekvation, där relationerna kan beskrivas som en del-helhetsstruktur.
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| 8. |
- Andersson, Catrine, et al.
(författare)
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More-Than-Two-Parent Families : Displaying Legitimate Parenthood in Swedish Media
- 2019
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Ingår i: Lambda Nordica. - : Föreningen Lambda Nordica. - 1100-2573 .- 2001-7286. ; 24:2-3, s. 81-103
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Tidskriftsartikel (refereegranskat)abstract
- Norms concerning family formation are generally based on ideals of coupled love and the two-parent-family, however, family practices frequently go beyond these norms. Families consisting of more than two parents that are co-parenting have only been studied to a small extent. Analysing Swedish newspaper and magazine articles on more-than-two-parent families between 1992 and 2016 we ask: How are more-than-two-parent families displayed in Swedish media stories? Are they portrayed as legitimate families, and if so, how is this legitimacy discursively constructed? What role does recognition play in the media stories and how is it negotiated in the narratives? We use the concepts display (Finch 2007) and recognition/redistribution (Fraser 1998; 2003) in exploring the significance that recognition and legitimacy have for the depiction of families with more than two parents in the media material. The display of more-than-two-parent families in the Swedish media stories analysed is generally characterised by repertoires of modern family life, of love and intimacy and responsible and successful parenting. These repertoires are used to display the families as normal, modern, and legitimate. In addition to the repertoires mentioned, there are repertoires of importance of geographical location, of strategies and of critique of current legislation that further emphasise the legitimacy of the more-than-two-parent families in contrast to an outdated legislation that forces these legitimate families to strategise their intimate relationships. Despite several of the people interviewed being described as polyamorous or gay/lesbian, there are no tendencies in the empirical material to motivate the need for rights based on an essentialised polyamorous identity; rather, the focus is on the fact that it is the practical care relations that need to be protected.
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| 9. |
- Andersson, Charlotta, et al.
(författare)
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Phase-contrast MRI volume flow - a comparison of breath held and navigator based acquisitions
- 2016
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Ingår i: BMC Medical Imaging. - : BioMed Central. - 1471-2342. ; 16:26
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Tidskriftsartikel (refereegranskat)abstract
- Background: Magnetic Resonance Imaging (MRI) 2D phase-contrast flow measurement has been regarded as the gold standard in blood flow measurements and can be performed with free breathing or breath held techniques. We hypothesized that the accuracy of flow measurements obtained with segmented phase-contrast during breath holding, and in particular higher number of k-space segments, would be non-inferior compared to navigator phase-contrast. Volumes obtained from anatomic segmentation of cine MRI and Doppler echocardiography were used for additional reference. Methods: Forty patients, five women and 35 men, mean age 65 years (range 53-80), were randomly selected and consented to the study. All underwent EKG-gated cardiac MRI including breath hold cine, navigator based free-breathing phase-contrast MRI and breath hold phase-contrast MRI using k-space segmentation factors 3 and 5, as well as transthoracic echocardiography within 2 days. Results: In navigator based free-breathing phase-contrast flow, mean stroke volume and cardiac output were 79.7 +/- 17.1 ml and 5071 +/- 1192 ml/min, respectively. The duration of the acquisition was 50 +/- 6 s. With k-space segmentation factor 3, the corresponding values were 77.7 ml +/- 17.5 ml and 4979 +/- 1211 ml/min (p = 0.15 vs navigator). The duration of the breath hold was 17 +/- 2 s. K-space segmentation factor 5 gave mean stroke volume 77.9 +/- 16.4 ml, cardiac output 5142 +/- 1197 ml/min (p = 0.33 vs navigator), and breath hold time 11 +/- 1 s. Anatomical segmentation of cine gave mean stroke volume and cardiac output 91.2 +/- 20.8 ml and 5963 +/- 1452 ml/min, respectively. Echocardiography was reliable in 20 of the 40 patients. The mean diameter of the left ventricular outflow tract was 20.7 +/- 1.5 mm, stroke volume 78.3 ml +/- 15.2 ml and cardiac output 5164 +/- 1249 ml/min. Conclusions: In forty consecutive patients with coronary heart disease, breath holding and segmented k-space sampling techniques for phase-contrast flow produced stroke volumes and cardiac outputs similar to those obtained with free-breathing navigator based phase-contrast MRI, using less time. The values obtained agreed fairly well with Doppler echocardiography while there was a larger difference when compared with anatomical volume determinations using SSFP (steady state free precession) cine MRI.
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| 10. |
- Andersson, Catrine, et al.
(författare)
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Polyamorous Parenthood – Kinship, Gender and Morality
- 2021
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Ingår i: Close Relations. - New York : Springer. - 9789811607929 - 9789811607912 ; , s. 139-153
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Research on polyamorous parenthood has mainly focused on aspects of interactions with schools and authorities, where polyamorous parents have had to develop strategies of openness and concealment and dealing with stigmatization (Palotta-Chiarolla 2010; Riggs 2010; Sheff 2010). Aspects of sex and morality have primarily been explored in general in relation to non-monogamous practice and not specifically in relation to parenthood (Ritchie 2010; Samuels 2010). Based on interviews with 22 persons in Sweden who in different ways have experience of non-monogamous practice, we explore polyamorous parenthood, focusing on kinship practices, gender and sexual morality. The results of these analyses show that there are recurring themes of promiscuity as a risk that polyamorous parents have to handle. This can take the form of negative interactions with family members and society, practical issues with having sex with several partners or identity issues where good parenthood risks being at odds with non-monogamous practices. The boundaries of good parenthood and promiscuity and the negotiations between them are rarely highlighted in research, but have implications for the moral order of kinship for non-monogamous practice today.
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