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Sökning: WFRF:(Andiappan AK)

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Numrering	Referens	Omslagsbild	Hitta
1.	Nilsson, Daniel, et al. (författare) Poor reproducibility of allergic rhinitis SNP associations 2013 Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 8:1, s. e53975- Tidskriftsartikel (refereegranskat)abstract Replication of reported associations is crucial to the investigation of complex disease. More than 100 SNPs have previously been reported as associated with allergic rhinitis (AR), but few of these have been replicated successfully. To investigate the general reproducibility of reported AR-associations in candidate gene studies, one Swedish (352 AR-cases, 709 controls) and one Singapore Chinese population (948 AR-cases, 580 controls) were analyzed using 49 AR-associated SNPs. The overall pattern of P-values indicated that very few of the investigated SNPs were associated with AR. Given published odds ratios (ORs) most SNPs showed high power to detect an association, but no correlations were found between the ORs of the two study populations or with published ORs. None of the association signals were in common to the two genome-wide association studies published in AR, indicating that the associations represent false positives or have much lower effect-sizes than reported.
2.	Andiappan, AK, et al. (författare) Integration of high-dimensional-omics reveals novel predictive signatures and candidate pathways for allergic rhinitis (AR) 2019 Ingår i: ALLERGY. - 0105-4538. ; 74, s. 170-171 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
3.	Andiappan, AK, et al. (författare) Inverse association of FCER1A allergy variant in monocytes and plasmacytoid dendritic cells 2021 Ingår i: The Journal of allergy and clinical immunology. - 1097-6825. ; 147:4, s. 1510-1513.e8 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
4.	Farzan, N, et al. (författare) Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium 2017 Ingår i: Pharmacogenomics. - : Future Medicine Ltd. - 1744-8042 .- 1462-2416. ; 18:10, s. 931-943 Tidskriftsartikel (refereegranskat)abstract Aim: International collaboration is needed to enable large-scale pharmacogenomics studies in childhood asthma. Here, we describe the design of the Pharmacogenomics in Childhood Asthma (PiCA) consortium. Materials & methods: Investigators of each study participating in PiCA provided data on the study characteristics by answering an online questionnaire. Results: A total of 21 studies, including 14,227 children/young persons (58% male), from 12 different countries are currently enrolled in the PiCA consortium. Fifty six percent of the patients are Caucasians. In total, 7619 were inhaled corticosteroid users. Among patients from 13 studies with available data on asthma exacerbations, a third reported exacerbations despite inhaled corticosteroid use. In the future pharmacogenomics studies within the consortium, the pharmacogenomics analyses will be performed separately in each center and the results will be meta-analyzed. Conclusion: PiCA is a valuable platform to perform pharmacogenetics studies within a multiethnic pediatric asthma population.
5.	Lee, WWL, et al. (författare) Eosinophilic allergic rhinitis is strongly associated with the CD45RBlo subset of CD161+ Th2 cells that secretes IL-2, IL-3, IL-4, IL-5, IL-9, and IL-13 2023 Ingår i: Allergy. - 1398-9995. Tidskriftsartikel (refereegranskat)
6.	Lee, WWL, et al. (författare) Eosinophilic allergic rhinitis is strongly associated with the CD45RBlo subset of CD161+ Th2 cells that secretes IL-2, IL-3, IL-4, IL-5, IL-9, and IL-13 2023 Ingår i: Allergy. - 1398-9995. ; 78:10, s. 2794-2798 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
7.	Lu, YX, et al. (författare) Biomarker Signatures Predicting 10-Year All-Cause and Disease-Specific Mortality 2019 Ingår i: The journals of gerontology. Series A, Biological sciences and medical sciences. - : Oxford University Press (OUP). - 1758-535X. ; 74:4, s. 469-479 Tidskriftsartikel (refereegranskat)

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Resultat 1-7 av 7

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Typ av publikation: tidskriftsartikel (6); konferensbidrag (1)

Typ av innehåll: refereegranskat (4); övrigt vetenskapligt/konstnärligt (3)

Författare/redaktör: Andiappan, AK (7); Melen, E (5); Rotzschke, O (5); Merid, SK (4); Lum, J (4); Foo, S (4); visa fler...; Zolezzi, F (4); Lee, B. (3); Puan, KJ (3); Yusof, N (3); Ong, J. (2); Poidinger, M (2); Wang, DY (2); Ang, R (2); Wang, Y. (1); Mukhopadhyay, S (1); Pino-Yanes, M (1); Kabesch, M (1); Maitland-van Der Zee ... (1); Bonnelykke, K (1); Bisgaard, H (1); Nilsson, D (1); Nilsson, Daniel (1); Cardell, Lars-Olaf (1); Cardell, LO (1); Koppelman, GH (1); Celedón, JC (1); Nilsson, S. (1); Kumar, D. (1); Choi, H. (1); Pirmohamed, M. (1); Halldén, Christer (1); Berce, V (1); Koh, HW (1); San Luis, B (1); Khor, CC (1); Yeow, PT (1); Koh, G (1); , Anonymous] (1); Andiappan, Anand Kum ... (1); Säll, Torbjörn (1); Tim, Chew Fook (1); Flores, C (1); Vijverberg, SJ (1); Lu, YX (1); Hernandez-Pacheco, N (1); Larbi, A (1); Wang, De Yun (1); Burchard, EG (1); Duijts, L (1); visa färre...

Lärosäte: Karolinska Institutet (6); Högskolan Kristianstad (1); Lunds universitet (1)

Språk: Engelska (7)

Forskningsämne (UKÄ/SCB): Naturvetenskap (1)

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