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| 2. |
- Andreasson, Anna, et al.
(författare)
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Brief report : Contemplate your symptoms and re-evaluate your health. A study on working adults
- 2019
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Ingår i: Journal of Health Psychology. - : SAGE Publications. - 1359-1053 .- 1461-7277. ; 24:11, s. 1562-1567
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Tidskriftsartikel (refereegranskat)abstract
- We investigated whether self-ratings of health are affected by a symptom rating. A diary including a one-item self-rating of health ("pre-self-rated health"; 1 = excellent, 7 = very poor), a subsequent 26-item rating of symptoms, and thereafter a second (identical) health rating ("post-self-rated health") was completed by 820 persons 21 times. Self-rated health worsened significantly ( p < .0001) after the symptom rating, from 2.72 pre-self-rated health (95% confidence interval: 2.70-2.74) to 2.77 post-self-rated health (95% confidence interval: 2.75-2.79) and more so in persons who reported more symptoms ( b = .058, p < .05). The results support the notion that subjective health perception is influenced by attending to symptoms, especially so in persons with a high symptom burden.
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| 3. |
- Andreasson, Anna, et al.
(författare)
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The effect of a transient immune activation on subjective health perception in two placebo controlled randomised experiments
- 2019
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Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 14:3
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Tidskriftsartikel (refereegranskat)abstract
- Background Patient-reported outcomes predict mortality and play increasingly important roles in care, but factors that modify central measures such as health ratings have been little investigated. Building on designated immune-to-brain pathways, we aimed to determine how a short-term induced inflammation response impacts self-reported health status. Methods Lipopolysaccharide injections were used to provoke acute systemic inflammatory responses in healthy men and women and were compared to placebo in two double-blind randomized experiments. In Experiment 1, 8 individuals (mean 24 years; SD = 3.7) received lipopolysaccharide 0.8 ng/kg once and placebo once in a cross-over design, and in Experiment 2, 52 individuals received either lipopolysaccharide 0.6 ng/kg or placebo once (28.6 years; SD = 7.1). Main outcomes were perceived health (general and current), sickness behaviour (like fatigue, pain and negative affect), and plasma interleukin-6, interleukin-8 and tumour necrosis factor-alpha, before and after injection. Results Compared to placebo, lipopolysaccharide lead to a deterioration in both self-rated general (Experiment 1, b = 1.88 for 0.8 ng/kg) and current health (Experiment 1 b = -3.00; and Experiment 2 b = -1.79) 1.5h after injection (p's<0.01), effects that remained after 4.5 to 5 hours (p's<0.05). The effect on current health in Experiment 2 was mediated by increased inflammation and sickness behaviour in response to lipopolysaccharide injection (beta = -0.28, p = 0.01). Conclusion Health is drastically re-evaluated during inflammatory activation. The findings are consistent with notions that inflammation forms part of health-relevant interoceptive computations of bodily state, and hint at one mechanism as to why subjective health predicts longevity.
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| 5. |
- Andreasson, Torbjörn, et al.
(författare)
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Kriskommunikation 2032. Fyra samhällsscenarier för strategisk planering – SOMCRISC rapport 2
- 2017
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Forskningsprojektet Digitala och sociala mediers betydelse för kommunikation i samband med samhälleliga kriser (SOMCRISC) tar avstamp i den genomgripande digitalisering som skett i samhället under senare decennier. Fokus i projektet ligger på hur digital teknik öppnat för nya möjligheter och utmanat de förhållningssätt och praktiker som präglat kriskommunikation i samband med samhälleliga kriser. I de två rapporter som producerats tar projektet sikte på år 2032, de behov som framtida krishantering kan komma att ställas inför och de möjligheter och förutsättningar som den digitala tekniken kan tänkas tillhandahålla. Rapport 1, Kriskommunikation 2032 – Tolv trender i ett digitalt samhälle, redogör för ett antal trender kring digital teknik och tillämpning av digitala tjänster, som kan förväntas få stor betydelse för det svenska krishanteringssystemet. Utgångspunkten har varit att identifiera, analysera och redogöra för viktiga trender i gränssnittet mellan digitalisering å ena sidan, och medier, myndigheter och teknisk infrastruktur å andra sidan. Rapport 2, Kriskommunikation 2032 – Fyra samhällsscenarier för strategisk planering, är tänkt att fungera som ett metodstöd för proaktiv reflektion kring och analys av kriser i ett framtida digitalt samhälle. Baserat på tidigare forskning och domänexpertis presenterar rapporten fyra digitala framtidsscenarier, konstruerade kring dimensionerna medborgardeltagande och offentlig styrning.
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| 6. |
- Andreasson, Torbjörn, et al.
(författare)
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Kriskommunikation 2032. Tolv trender i ett digitalt samhälle – SOMCRISC rapport 1
- 2017
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Forskningsprojektet Digitala och sociala mediers betydelse för kommunikation i samband med samhälleliga kriser (SOMCRISC) tar avstamp i den genomgripande digitalisering som skett i samhället under senare decennier. Fokus i projektet ligger på hur digital teknik öppnat för nya möjligheter och utmanat de förhållningssätt och praktiker som präglat kriskommunikation i samband med samhälleliga kriser. I de två rapporter som producerats tar projektet sikte på år 2032, de behov som framtida krishantering kan komma att ställas inför och de möjligheter och förutsättningar som den digitala tekniken kan tänkas tillhandahålla. Rapport 1, Kriskommunikation 2032 – Tolv trender i ett digitalt samhälle, redogör för ett antal trender kring digital teknik och tillämpning av digitala tjänster, som kan förväntas få stor betydelse för det svenska krishanteringssystemet. Utgångspunkten har varit att identifiera, analysera och redogöra för viktiga trender i gränssnittet mellan digitalisering å ena sidan, och medier, myndigheter och teknisk infrastruktur å andra sidan. Rapport 2, Kriskommunikation 2032 – Fyra samhällsscenarier för strategisk planering, är tänkt att fungera som ett metodstöd för proaktiv reflektion kring och analys av kriser i ett framtida digitalt samhälle. Baserat på tidigare forskning och domänexpertis presenterar rapporten fyra digitala framtidsscenarier, konstruerade kring dimensionerna medborgardeltagande och offentlig styrning.
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| 7. |
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| 8. |
- Lasselin, Julie, et al.
(författare)
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Fatigue and sleepiness responses to experimental inflammation and exploratory analysis of the effect of baseline inflammation in healthy humans
- 2020
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Ingår i: Brain, behavior, and immunity. - : Elsevier BV. - 0889-1591 .- 1090-2139. ; 83, s. 309-314
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Tidskriftsartikel (refereegranskat)abstract
- Inflammation is believed to be a central mechanism in the pathophysiology of fatigue. While it is likely that dynamic of the fatigue response after an immune challenge relates to the corresponding cytokine release, this lacks evidence. Although both fatigue and sleepiness are strong signals to rest, they constitute distinct symptoms which are not necessarily associated, and sleepiness in relation to inflammation has been rarely investigated. Here, we have assessed the effect of an experimental immune challenge (administration of lipopolysaccharide, LPS) on the development of both fatigue and sleepiness, and the associations between increases in cytokine concentrations, fatigue and sleepiness, in healthy volunteers. In addition, because chronic-low grade inflammation may represent a risk factor for fatigue, we tested whether higher baseline levels of inflammation result in a more pronounced development of cytokine-induced fatigue and sleepiness. Data from four experimental studies was combined, giving a total of 120 subjects (LPS N = 79, 18 (23%) women; Placebo N = 69, 12 (17%) women). Administration of LPS resulted in a stronger increase in fatigue and sleepiness compared to the placebo condition, and the development of both fatigue and sleepiness closely paralleled the cytokine responses. Individuals with stronger increases in cytokine concentrations after LPS administration also suffered more from fatigue and sleepiness (N = 75), independent of gender. However, there was no support for the hypothesis that higher baseline inflammatory markers moderated the responses in fatigue or sleepiness after an inflammatory challenge. The results demonstrate a tight connection between the acute inflammatory response and development of both fatigue and sleepiness, and motivates further investigation of the involvement of inflammation in the pathophysiology of central fatigue.
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| 9. |
- Lundmark, Sonja, 1966, et al.
(författare)
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Heat transfer coefficients in a coupled 3-D model of a liquid-cooled IPM traction motor compared with measurements
- 2019
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Ingår i: 2019 14th International Conference on Ecological Vehicles and Renewable Energies, EVER 2019. - 9781728137032
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Konferensbidrag (refereegranskat)abstract
- Modelling of electrical machines is constantly refined and it is now possible to couple numerical thermal models and electromagnetic models, thereby considering the thermal effects on motor materials. In this paper it is shown how a 3-D model of an interior permanent magnet (IPM) motor, including losses in the end windings and the effect of air and liquid cooling can be made where simulation results are compared with measurements. Further, it is shown how the coolant inlet temperature and volumetric flow rate affects the heat transfer coefficient of the cooling duct for some load points within the torquespeed range of the motor.
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| 10. |
- Lundmark, Sonja, 1966, et al.
(författare)
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Heat transfer coefficients in a coupled 3-D model of a liquid-cooled IPM traction motor compared with measurements
- 2021
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Ingår i: IEEE Transactions on Industry Applications. - 0093-9994 .- 1939-9367. ; 57:5, s. 4805-4814
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Tidskriftsartikel (refereegranskat)abstract
- Modelling of electrical machines is constantly refined and it is now possible to couple numerical thermal models and electromagnetic models, thereby allowing to examine the thermal effects on motor materials. In this paper it is shown how a 3-D model of an interior permanent magnet (IPM) motor, including power loss in the end windings and the effect of air and liquid cooling can be made where simulation results are compared with measurements. Further, it is shown how the coolant inlet temperature and volumetric flow rate affects the heat transfer coefficient of the cooling duct for some load points within the torque-speed range of the motor.
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