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Sökning: WFRF:(Andremont Antoine)

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1.
  • Denamur, Erick, et al. (författare)
  • High frequency of mutator strains among human uropathogenic Escherichia coli isolates.
  • 2002
  • Ingår i: Journal of Bacteriology. - 0021-9193 .- 1098-5530. ; 184:2, s. 605-9
  • Tidskriftsartikel (refereegranskat)abstract
    • By using a panel of 603 commensal and pathogenic Escherichia coli and Shigella isolates, we showed that mutation rates of strains vary considerably among different ecotypes. Uropathogenic strains had the highest frequency of mutators, while strains from patients with bacteremia had the lowest mutation rates. No correlation between the mutation rates and antibiotic resistance was observed among the studied strains.
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  • Larsson, D. G. Joakim, 1969, et al. (författare)
  • Critical knowledge gaps and research needs related to the environmental dimensions of antibiotic resistance
  • 2018
  • Ingår i: Environment International. - : Elsevier BV. - 0160-4120 .- 1873-6750. ; 117, s. 132-138
  • Forskningsöversikt (refereegranskat)abstract
    • There is growing understanding that the environment plays an important role both in the transmission of antibiotic resistant pathogens and in their evolution. Accordingly, researchers and stakeholders world-wide seek to further explore the mechanisms and drivers involved, quantify risks and identify suitable interventions. There is a clear value in establishing research needs and coordinating efforts within and across nations in order to best tackle this global challenge. At an international workshop in late September 2017, scientists from 14 countries with expertise on the environmental dimensions of antibiotic resistance gathered to define critical knowledge gaps. Four key areas were identified where research is urgently needed: 1) the relative contributions of different sources of antibiotics and antibiotic resistant bacteria into the environment; 2) the role of the environment, and particularly anthropogenic inputs, in the evolution of resistance; 3) the overall human and animal health impacts caused by exposure to environmental resistant bacteria; and 4) the efficacy and feasibility of different technological, social, economic and behavioral interventions to mitigate environmental antibiotic resistance.(1)
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