SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Apelgren Karin) "

Sökning: WFRF:(Apelgren Karin)

  • Resultat 1-10 av 33
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  •  
2.
  • Amoroso, Matteo, 1984, et al. (författare)
  • Functional and morphological studies of in vivo vascularization of 3D-bioprinted human fat grafts
  • 2021
  • Ingår i: Bioprinting. - : Elsevier BV. - 2405-8866. ; 23
  • Tidskriftsartikel (refereegranskat)abstract
    • Three-dimensional (3D) bioprinting offers the ability to design and biofabricate 3D structures based on autologous fat; however, the lack of vascularization in larger 3D-bioprinted constructs represents a limiting factor that hampers translation of this technology from bench to bedside. 3D bioprinting using microfractured fat mixed with nanocellulose–alginate hydrogel can promote vascularization through connections of fragments of vessels included in the fat. In this study, we determined the perfusion and diffusion characteristics of 3D-bioprinted fat constructs using magnetic resonance imaging (MRI) and assessed correlations between perfusion and angiogenesis within the printed constructs. Microfractured human fat from liposuction was printed with tunicate nanocellulose–alginate hydrogel, followed by transplantation of the constructs (10 × 10 × 3 mm) into nude mice that underwent longitudinal MRI for up to 99 days. Confirmation of vascularization was undertaken using immunohistochemical and histologic analyses. Before implantation, the constructs contained abundant fat tissue and fragments of human blood vessels (CD31+ and Ku80+), with subsequent in vivo MRI analysis following transplantation indicating low perfusion and suggesting their continued survival mainly by diffusion. Additionally, we observed a high diffusion coefficient (~2 × 10−3 mm2/s) that was preserved throughout the observation period. Following explantation, evaluation revealed that the constructs displayed preserved histology along with a mixture of human (Ku80+) and murine (Ku80−) erythrocyte-containing vessels. These results demonstrated successful interconnection of blood-vessel fragments from microfractured human fat via angiogenesis to form a vascular network with the host circulation, thereby confirming vascularization of the 3D-bioprinted fat constructs.
  •  
3.
  • Amoroso, Matteo, 1984, et al. (författare)
  • The effect of hemodilution on free flap survival: A systematic review of clinical andexperimental studies.
  • 2020
  • Ingår i: Clinical hemorheology and microcirculation. - 1875-8622. ; 75:4, s. 457-466
  • Forskningsöversikt (refereegranskat)abstract
    • Acute normovolemic hemodilution (ANH) has been proposed as a microsurgical technique to improve blood flow in free flaps.Here, we present the first systematic review of clinical and experimental studies on the effect of ANH.We performed a systematic literature search of PubMed, Medline, the Cochrane Library, Google Scholar, and ClinicalTrials.gov using search strategies and a review process in agreement with the PRISMA statement and the Cochrane Handbook for systematic reviews of interventions. PICO criteria were defined before bibliometric processing of the retrieved articles, which were analyzed with the SYRCLE RoB tool for risk of bias and the GRADE scale for level of evidence.We retrieved 74 articles from the literature search, and after processing according to PICO criteria, only four articles remained, all of which were experimental. The rating for risk of bias was uncertain according to SYRCLE RoB results, and the level of evidence was low according to GRADE evaluation.There is no clinical evidence for the effect of ANH on microcirculation in free flaps, and experimental studies provide weak evidence supporting the use of hemodilution in reconstructive microsurgery.
  •  
4.
  •  
5.
  •  
6.
  •  
7.
  •  
8.
  •  
9.
  •  
10.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 33
Typ av publikation
konferensbidrag (12)
tidskriftsartikel (11)
annan publikation (4)
rapport (2)
bok (1)
doktorsavhandling (1)
visa fler...
forskningsöversikt (1)
bokkapitel (1)
visa färre...
Typ av innehåll
refereegranskat (20)
övrigt vetenskapligt/konstnärligt (13)
Författare/redaktör
Apelgren, Karin (17)
Apelgren, Peter (13)
Gatenholm, Paul, 195 ... (11)
Kölby, Lars, 1963 (10)
Säljö, Karin, 1981 (10)
Ryegård, Åsa (7)
visa fler...
Olsson, Thomas (7)
Strid Orrhult, Linne ... (6)
Amoroso, Matteo, 198 ... (6)
Henriksson, Ann-Sofi ... (5)
Sämfors, Sanna, 1987 (5)
Troedsson, Christofe ... (3)
Kolby, Lars (3)
Oldsjö, Fredrik (2)
Lindahl, Anders, 195 ... (2)
Elmgren, Maja, 1964- (2)
Simonsson, Stina, 19 ... (2)
Thompson, Eric M (2)
Brantsing, Camilla (2)
Markstedt, Kajsa, 19 ... (2)
Winka, Katarina, 197 ... (2)
Winka, Katarina (2)
Birgegård, Gunnar (1)
Niemi, Essi M. (1)
Scholz, Hanne (1)
Lindahl, A. (1)
Elander, Anna, 1955 (1)
Mårtensson, Katarina (1)
Roxå, Torgny (1)
Lindahl, Anders (1)
Montelius, Mikael (1)
Engström, Mona (1)
Gatenholm, P (1)
Montelius, Mikael, 1 ... (1)
Elmgren, Maja (1)
Johansson, Jakob (1)
Apelgren, Karin, 196 ... (1)
Apelgren, Karin, 196 ... (1)
Apelgren, Karin Blüc ... (1)
1961-, Edström (1)
Kristina, (1)
Edström, Kristina Lö ... (1)
Mölne, Johan (1)
Brantsing, C. (1)
Stridh Orrhult, L. (1)
Amoroso, Matteo (1)
Saeljoe, Karin (1)
Li, Susann, 1962 (1)
Erhardsson, Margaret ... (1)
Rügheimer, Louise (1)
visa färre...
Lärosäte
Uppsala universitet (13)
Chalmers tekniska högskola (11)
Göteborgs universitet (10)
Lunds universitet (5)
Umeå universitet (2)
Språk
Engelska (28)
Svenska (5)
Forskningsämne (UKÄ/SCB)
Samhällsvetenskap (14)
Medicin och hälsovetenskap (12)
Teknik (8)
Naturvetenskap (4)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy