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Sökning: WFRF:(Ashokkumar M.)

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1.
  • Patel, Jayshil Ashokkumar, et al. (författare)
  • CHEOPS and TESS view of the ultra-short-period super-Earth TOI-561 b
  • 2023
  • Ingår i: Astronomy and Astrophysics. - 0004-6361 .- 1432-0746. ; 679
  • Tidskriftsartikel (refereegranskat)abstract
    • Context. Ultra-short-period planets (USPs) are a unique class of super-Earths with an orbital period of less than a day, and hence they are subject to intense radiation from their host star. These planets cannot retain a primordial H/He atmosphere, and most of them are indeed consistent with being bare rocky cores. A few USPs, however, show evidence for a heavyweight envelope, which could be a water layer resilient to evaporation or a secondary metal-rich atmosphere sustained by outgassing of the molten volcanic surface. Much thus remains to be learned about the nature and formation of USPs. Aims. The prime goal of the present work is to refine the bulk planetary properties of the recently discovered TOI-561 b through the study of its transits and occultations. This is crucial in order to understand the internal structure of this USP and to assess the presence of an atmosphere. Methods. We obtained ultra-precise transit photometry of TOI-561 b with CHEOPS, and performed a joint analysis of these data along with three archival visits from CHEOPS and four TESS sectors. Results. Our analysis of TOI-561 b transit photometry put strong constraints on its properties. In particular, we restrict the uncertainties on the planetary radius at similar to 2% retrieving R-p = 1.42 +/- 0.02 R-circle plus. This result informs our internal structure modelling of the planet, which shows that the observations are consistent with a negligible H/He atmosphere; however, other lighter materials are required, in addition to a pure iron core and a silicate mantle, to explain the observed density. We find that this can be explained by the inclusion of a water layer in our model. Additionally, we ran a grid of forward models with a water-enriched atmosphere to explain the transit radius. We searched for variability in the measured R-p/R-star over time, which could trace changes in the structure of the planetary envelope. However, no temporal variations are recovered within the present data precision. In addition to the transit event, we tentatively detect an occultation signal in the TESS data with an eclipse depth L = 27.40(-11.35)(+10.87) ppm. We use models of outgassed atmospheres from the literature to explain this eclipse signal. We find that the thermal emission from the planet can mostly explain the observation. Based on this, we predict that near- to mid-infrared observations with the James Webb Space Telescope should be able to detect silicate species in the atmosphere of the planet. This could also reveal important clues about the planetary interior and help disentangle planet formation and evolution models.
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2.
  • Demory, B.O., et al. (författare)
  • 55 Cancri e's occultation captured with CHEOPS
  • 2023
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 669
  • Tidskriftsartikel (refereegranskat)abstract
    • Past occultation and phase-curve observations of the ultra-short period super-Earth 55 Cnc e obtained at visible and infrared wavelengths have been challenging to reconcile with a planetary reflection and emission model. In this study, we analyse a set of 41 occultations obtained over a two-year timespan with the CHEOPS satellite. We report the detection of 55 Cnc e's occultation with an average depth of 12 ± 3 ppm. We derive a corresponding 2Ïà  upper limit on the geometric albedo of Ag < 0.55 once decontaminated from the thermal emission measured by Spitzer at 4.5 μm. CHEOPSâà €à ™ s photometric performance enables, for the first time, the detection of individual occultations of this super-Earth in the visible and identifies short-timescale photometric corrugations likely induced by stellar granulation. We also find a clear 47.3-day sinusoidal pattern in the time-dependent occultation depths that we are unable to relate to stellar noise, nor instrumental systematics, but whose planetary origin could be tested with upcoming JWST occultation observations of this iconic super-Earth.
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3.
  • Brandeker, Alexis, et al. (författare)
  • CHEOPS geometric albedo of the hot Jupiter HD 209458 b
  • 2022
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 659
  • Tidskriftsartikel (refereegranskat)abstract
    • We report the detection of the secondary eclipse of the hot Jupiter HD 209458 b in optical/visible light using the CHEOPS space telescope. Our measurement of 20.4+3.2-3.3 parts per million translates into a geometric albedo of Ag = 0.096 ± 0.016. The previously estimated dayside temperature of about 1500 K implies that our geometric albedo measurement consists predominantly of reflected starlight and is largely uncontaminated by thermal emission. This makes the present result one of the most robust measurements of Ag for any exoplanet. Our calculations of the bandpass-integrated geometric albedo demonstrate that the measured value of Ag is consistent with a cloud-free atmosphere, where starlight is reflected via Rayleigh scattering by hydrogen molecules, and the water and sodium abundances are consistent with stellar metallicity. We predict that the bandpass-integrated TESS geometric albedo is too faint to detect and that a phase curve of HD 209458 b observed by CHEOPS would have a distinct shape associated with Rayleigh scattering if the atmosphere is indeed cloud free.
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4.
  • Krenn, A., et al. (författare)
  • The geometric albedo of the hot Jupiter HD 189733b measured with CHEOPS
  • 2023
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 672
  • Tidskriftsartikel (refereegranskat)abstract
    • Context. Measurements of the occultation of an exoplanet at visible wavelengths allow us to determine the reflective properties of a planetary atmosphere. The observed occultation depth can be translated into a geometric albedo. This in turn aids in characterising the structure and composition of an atmosphere by providing additional information on the wavelength-dependent reflective qualities of the aerosols in the atmosphere. Aims. Our aim is to provide a precise measurement of the geometric albedo of the gas giant HD 189733b by measuring the occultation depth in the broad optical bandpass of CHEOPS (350-1100 nm). Methods. We analysed 13 observations of the occultation of HD 189733b performed by CHEOPS utilising the Python package PyCHEOPS. The resulting occultation depth is then used to infer the geometric albedo accounting for the contribution of thermal emission from the planet. We also aid the analysis by refining the transit parameters combining observations made by the TESS and CHEOPS space telescopes. Results. We report the detection of an 24.7 ± 4.5 ppm occultation in the CHEOPS observations. This occultation depth corresponds to a geometric albedo of 0.076 ± 0.016. Our measurement is consistent with models assuming the atmosphere of the planet to be cloud-free at the scattering level and absorption in the CHEOPS band to be dominated by the resonant Na doublet. Taking into account previous optical-light occultation observations obtained with the Hubble Space Telescope, both measurements combined are consistent with a super-stellar Na elemental abundance in the dayside atmosphere of HD 189733b. We further constrain the planetary Bond albedo to between 0.013 and 0.42 at 3σconfidence. Conclusions. We find that the reflective properties of the HD 189733b dayside atmosphere are consistent with a cloud-free atmosphere having a super-stellar metal content. When compared to an analogous CHEOPS measurement for HD 209458b, our data hint at a slightly lower geometric albedo for HD 189733b (0.076 ± 0.016) than for HD 209458b (0.096 ± 0.016), or a higher atmospheric Na content in the same modelling framework. While our constraint on the Bond albedo is consistent with previously published values, we note that the higher-end values of ∼0.4, as derived previously from infrared phase curves, would also require peculiarly high reflectance in the infrared, which again would make it more difficult to disentangle reflected and emitted light in the total observed flux, and therefore to correctly account for reflected light in the interpretation of those phase curves. Lower reported values for the Bond albedos are less affected by this ambiguity.
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6.
  • Ashokkumar, M, et al. (författare)
  • In vitro replicative fitness of early Transmitted founder HIV-1 variants and sensitivity to Interferon alpha
  • 2020
  • Ingår i: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 10:1, s. 2747-
  • Tidskriftsartikel (refereegranskat)abstract
    • Type I interferons, particularly interferon-alpha (IFN-α), play a vital role in the host's anti-viral defenses by interfering with viral replication. However, the virus rapidly evolves to exploit the IFN-α response for its replication, spread, and pathogenic function. In this study, we attempted to determine IFN-α susceptibility and productivity of infectious transmitted/founder (TF) (n = 8) and non-transmitted (NT) viruses (n = 8) derived from HIV-1 infected infants. Independent experiments were carried out to determine IFN-α resistance, replication fitness, and viral productivity in CD4+ T cells over a short period. In vitro studies showed that TF viruses were resistant to IFN-α during the very near moment of transmission, but in the subsequent time points, they became susceptible to IFN-α. We did not observe much difference in replicative fitness of the TF viruses in cultures treated with and without IFN-α, but the difference was significant in the case of NT viruses obtained from the same individual. Despite increased susceptibility to IFN-α, NT viruses produced more viral particles than TF viruses. Similar results were also obtained in cultures treated with maraviroc (MVC). The study identified unique characteristics of TF viruses thus prompting further investigation into virus-host interaction occurring during the early stages of HIV infection.
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8.
  • Aralaguppe, SG, et al. (författare)
  • MiDRMpol: A High-Throughput Multiplexed Amplicon Sequencing Workflow to Quantify HIV-1 Drug Resistance Mutations against Protease, Reverse Transcriptase, and Integrase Inhibitors
  • 2019
  • Ingår i: Viruses. - : MDPI AG. - 1999-4915. ; 11:9
  • Tidskriftsartikel (refereegranskat)abstract
    • The detection of drug resistance mutations (DRMs) in minor viral populations is of potential clinical importance. However, sophisticated computational infrastructure and competence for analysis of high-throughput sequencing (HTS) data lack at most diagnostic laboratories. Thus, we have proposed a new pipeline, MiDRMpol, to quantify DRM from the HIV-1 pol region. The gag-vpu region of 87 plasma samples from HIV-infected individuals from three cohorts was amplified and sequenced by Illumina HiSeq2500. The sequence reads were adapter-trimmed, followed by analysis using in-house scripts. Samples from Swedish and Ethiopian cohorts were also sequenced by Sanger sequencing. The pipeline was validated against the online tool PASeq (Polymorphism Analysis by Sequencing). Based on an error rate of <1%, a value of >1% was set as reliable to consider a minor variant. Both pipelines detected the mutations in the dominant viral populations, while discrepancies were observed in minor viral populations. In five HIV-1 subtype C samples, minor mutations were detected at the <5% level by MiDRMpol but not by PASeq. MiDRMpol is a computationally as well as labor efficient bioinformatics pipeline for the detection of DRM from HTS data. It identifies minor viral populations (<20%) of DRMs. Our method can be incorporated into large-scale surveillance of HIV-1 DRM.
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