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- Autio, U.A., et al.
(författare)
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Magnetotelluric array in the central Finnish Lapland II : 3-D inversion and tectonic implications
- 2020
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Ingår i: Tectonophysics. - : Elsevier. - 0040-1951 .- 1879-3266. ; 794
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Tidskriftsartikel (refereegranskat)abstract
- The northern part of the Fennoscandian shield records several Palaeoproterozoic phases of rifting, crustal shortening, metamorphism and structural reactivation. The geologic history has left behind a complex crustal geoelectric structure as evidenced by magnetotelluric (MT) data from the central Finnish Lapland acquired in the context of the MaSca-project in 2014. The data are characterized by strong 3-D effects such as high phase tensor skew values and anomalous induction vectors. Interestingly, however, at the same time a dominant E-W principal direction from the phase tensor data can be inferred. 3-D conductivity models derived using the ModEM code display, high crustal conductance (> 10,000 S) in the vicinity of the Central Lapland Greenstone Belt, the Peräpohja Belt and the Kuusamo Belt. Conductors in the northern and southern part of the study area are separated by a resistor coinciding with the Central Lapland Granitoid Complex. A remarkable feature is an arc-shaped conductor inside the northern part of the Central Lapland Granitoid Complex, which continues into the Central Lapland Greenstone Belt in the north. The conductor is associated with a major induction vector anomaly and also coincides with extreme responses (negative phase tensor principal values), which are discussed in an accompanying paper. The conductive structures in the models are interpreted as deeply buried graphite and sulphide bearing metasedimentary rocks or as reactivated Archaean shear zones. The revealed geoelectric structures also partly correlate with seismic reflection and other geophysical data from the area. A possible explanation for the observed pervasive E-W principal direction of the phase tensor data could be the aulacogen (failed rift) suggested in recent tectonic evolution models.
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- Kylkilahti, E., et al.
(författare)
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Co-developing sustainability - a consumer-inclusive approach to wooden housing business in Finland
- 2024
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Ingår i: Housing Studies. - : Informa UK Limited. - 0267-3037 .- 1466-1810. ; 39:5, s. 1219-1238
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Tidskriftsartikel (refereegranskat)abstract
- The housing construction industry can address sustainability issues by developing its business practices. This requires a shift from a firm-driven business logic to a consumer-inclusive approach where consumers and businesses together enhance sustainable development. By analyzing data from focus group discussions with both industry experts in the wooden multi-storey construction business and consumers residing in novel wooden buildings, this study examines how businesses can engage consumers in the development of sustainable housing. The results are presented as an iterative dialogue process that acknowledges consumers as important actors to whom innovative housing solutions should be appropriately introduced and whose lived experiences need to be understood. The findings indicate that consumer experiences can feed the creation and uptake of innovations that enhance sustainability in the construction sector. The study fosters the material aspect of sustainable housing and, by highlighting consumer participation and communication, proposes tools for its consumer-inclusive co-development.
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- Mukherjee, SP, et al.
(författare)
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Macrophage sensing of single-walled carbon nanotubes via Toll-like receptors
- 2018
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Ingår i: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 8:1, s. 1115-
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Tidskriftsartikel (refereegranskat)abstract
- Carbon-based nanomaterials including carbon nanotubes (CNTs) have been shown to trigger inflammation. However, how these materials are ‘sensed’ by immune cells is not known. Here we compared the effects of two carbon-based nanomaterials, single-walled CNTs (SWCNTs) and graphene oxide (GO), on primary human monocyte-derived macrophages. Genome-wide transcriptomics assessment was performed at sub-cytotoxic doses. Pathway analysis of the microarray data revealed pronounced effects on chemokine-encoding genes in macrophages exposed to SWCNTs, but not in response to GO, and these results were validated by multiplex array-based cytokine and chemokine profiling. Conditioned medium from SWCNT-exposed cells acted as a chemoattractant for dendritic cells. Chemokine secretion was reduced upon inhibition of NF-κB, as predicted by upstream regulator analysis of the transcriptomics data, and Toll-like receptors (TLRs) and their adaptor molecule, MyD88 were shown to be important for CCL5 secretion. Moreover, a specific role for TLR2/4 was confirmed by using reporter cell lines. Computational studies to elucidate how SWCNTs may interact with TLR4 in the absence of a protein corona suggested that binding is guided mainly by hydrophobic interactions. Taken together, these results imply that CNTs may be ‘sensed’ as pathogens by immune cells.
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- Perkmann, M., et al.
(författare)
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Academic engagement and commercialisation: A review of the literature on university-industry relations
- 2013
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Ingår i: Research Policy. - : Elsevier BV. - 0048-7333 .- 1873-7625. ; 42:2, s. 423-442
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Tidskriftsartikel (refereegranskat)abstract
- A considerable body of work highlights the relevance of collaborative research, contract research, consulting and informal relationships for university–industry knowledge transfer. We present a systematic review of research on academic scientists’ involvement in these activities to which we refer as ‘academic engagement’. Apart from extracting findings that are generalisable across studies, we ask how academic engagement differs from commercialisation, defined as intellectual property creation and academic entrepreneurship. We identify the individual, organisational and institutional antecedents and consequences of academic engagement, and then compare these findings with the antecedents and consequences of commercialisation. Apart from being more widely practiced, academic engagement is distinct from commercialisation in that it is closely aligned with traditional academic research activities, and pursued by academics to access resources supporting their research agendas. We conclude by identifying future research needs, opportunities for methodological improvement and policy interventions.
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