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- Axel-Nilsson, Malin, et al.
(författare)
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Perceived relevance of selected behavioural traits in horses - A survey conducted in Sweden
- 2015
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Ingår i: Acta Agriculturae Scandinavica, Section A - Animal Science. - : Informa UK Limited. - 0906-4702 .- 1651-1972. ; 65, s. 23-32
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Tidskriftsartikel (refereegranskat)abstract
- In the present study, a web-based questionnaire was used with the aim to investigate perceived relevance of 14 behavioural traits in horses regarding quality of match between horse and rider. The responses of approximately 2800 participants indicate a high interest in the topic. All traits were considered relevant by at least 50% of the respondents. 'Easy to bring to new environments' was the trait indicated as relevant by the highest proportion (85%) of respondents, followed by 'spirited and forward' (84%) and 'tolerant towards humans' (80%). Respondents' age as well as preferred equitation discipline was shown to have a profound influence on perception of relevance (P < 0.05). The results suggest a need for methods to objectively evaluate individual differences in behavioural traits to enable selection of horses to optimize horse-rider match.
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- Axel-Nilsson, Malin
(författare)
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The match between horse and rider
- 2015
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- A successful relationship between horse and rider is a partnership based on compatibility and is often referred to as a good match. In the present thesis, ‘match’ includes the good interaction, interplay and cooperation between horse and rider as well as the related positive experience. A good horse-rider match is important for horse welfare, rider safety and good performance. The aim of this thesis was to investigate which parameters riders consider important for a good match, if horse temperament and rider personality affect the horse-rider match, and how this can be measured. Using a survey, the first study showed that riders consider behavioural traits as relevant to a good horse-rider match. It was shown that both age, preferred equitation discipline and to some extent level of experience had an influence on the riders’ opinion of which behavioural traits in horses were most relevant. The second study included a battery of behavioural tests designed to measure individual differences in response to challenges including human approach, isolation, handling and a novel object. The horses showed consistent responses between repetitions of the tests and could be divided in four temperamental categories. The third and final study investigated how quality in horse-rider match is affected by the combination of rider personality and horse temperament, and how this can be measured. Horses-rider dyads with different combinations of rider personality and horse temperament underwent tests including both handling and riding. Three types of indicators to measure and evaluate match were identified and applied: A) rider perception B) horse behaviour and C) the horse-rider combination’s effectiveness in accomplishing a task together. It was shown that rider personality and horse temperament have an effect on match quality, as measured with change in riders’ level of positive affect. This thesis provides a stepping stone to obtain a deeper insight into how good horse-rider match is defined, measured and realised. Harmonisation in the descriptions of match and horse behaviour and further development of appropriate measures is needed.
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- Janke, Axel, et al.
(författare)
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The mitochondrial genomes of the iguana (Iguana iguana) and the caiman (Caiman crocodylus): implications for amniote phylogeny
- 2001
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Ingår i: Royal Society of London. Proceedings B. Biological Sciences. - : The Royal Society. - 1471-2954. ; 268:1467, s. 623-631
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Tidskriftsartikel (refereegranskat)abstract
- The complete mitochondrial genomes of two reptiles, the common iguana (Iguana iguana) and the caiman (Caiman crocodylus), were sequenced in order to investigate phylogenetic questions of tetrapod evolution. The addition of the two species allows analysis of reptilian relationships using data sets other than those including only fast-evolving species. The crocodilian mitochondrial genomes seem to have evolved generally at a higher rate than those of other vertebrates. Phylogenetic analyses of 2889 amino-acid sites from 35 mitochondrial genomes supported the bird-crocodile relationship, lending no support to the Haematotherma hypothesis (with birds and mammals representing sister groups). The analyses corroborated the view that turtles are at the base of the bird-crocodile branch. This position of the turtles makes Diapsida paraphyletic. The origin of the squamates was estimated at 294 million years (Myr) ago and that of the turtles at 278 Myr ago. Phylogenetic analysis of mammalian relationships using the additional outgroups corroborated the Marsupionta hypothesis, which joins the monotremes and the marsupials to the exclusion of the eutherians.
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- Landquist, Birgit, et al.
(författare)
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Uppdaterad och utökad livscykelanalys av svensk grisproduktion
- 2020
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Förbättrade produktionsresultat inom svensk grisproduktion, användning av biproduk-ter och djurhälsans betydelse har analyserats i en livscykelanalys. Klimatavtrycket för kött från en svensk medelgris är 2,54 kg koldioxidekvivalenter/kg slaktvikt, vilket är bland de lägsta jämfört med tillgängliga internationella studier. Produktionen av foder står för 54 % av klimatavtrycket och hanteringen av stallgödsel för 36 %. Av foderstaten till den svenska integrerade medelslaktgrisen utgjorde biprodukter 10 % och soja 4 %. Baserat på antalet dagars förlängd uppfödningstid för sjuka grisar, visar vi att 3,4 % av klimatavtrycket beror på ökad foderförbrukning orsakad av fyra utvalda sjukdomar i svenska grisbesättningar. Produktionshöjande åtgärder såsom exempelvis friska grisar och hög fodereffektivitet, övergång till förnybara bränslen inom såväl odling av foder som inom grisuppfödning är viktiga åtgärder för att minska klimatavtrycket givet att det inte påverkar andra miljöaspekter, djurhälsa eller djurvälfärd negativt. En central aspekt är fortsatt utveckling mot välbalanserade foderstater med val av foderråvaror med lågt klimatavtryck, användning av biprodukter och inhemska fodergrödor odlade på ett hållbart sätt.
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- Olofsson Bagge, Roger, et al.
(författare)
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Isolated Hepatic Perfusion With Melphalan for Patients With Isolated Uveal Melanoma Liver Metastases : A Multicenter, Randomized, Open-Label, Phase III Trial (the SCANDIUM Trial)
- 2023
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Ingår i: Journal of Clinical Oncology. - : American Society of Clinical Oncology (ASCO). - 0732-183X .- 1527-7755. ; 41:16, s. 3042-3050
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: About half of patients with metastatic uveal melanoma present with isolated liver metastasis, in whom the median survival is 6-12 months. The few systemic treatment options available only moderately prolong survival. Isolated hepatic perfusion (IHP) with melphalan is a regional treatment option, but prospective efficacy and safety data are lacking.METHODS: In this multicenter, randomized, open-label, phase III trial, patients with previously untreated isolated liver metastases from uveal melanoma were randomly assigned to receive a one-time treatment with IHP with melphalan or best alternative care (control group). The primary end point was overall survival at 24 months. Here, we report the secondary outcomes of response according to RECIST 1.1 criteria, progression-free survival (PFS), hepatic PFS (hPFS), and safety.RESULTS: Ninety-three patients were randomly assigned, and 87 patients were assigned to either IHP (n = 43) or a control group receiving the investigator's choice of treatment (n = 44). In the control group, 49% received chemotherapy, 39% immune checkpoint inhibitors, and 9% locoregional treatment other than IHP. In an intention-to-treat analysis, the overall response rates (ORRs) were 40% versus 4.5% in the IHP and control groups, respectively (P < .0001). The median PFS was 7.4 months versus 3.3 months (P < .0001), with a hazard ratio of 0.21 (95% CI, 0.12 to 0.36), and the median hPFS was 9.1 months versus 3.3 months (P < .0001), both favoring the IHP arm. There were 11 treatment-related serious adverse events in the IHP group compared with seven in the control group. There was one treatment-related death in the IHP group.CONCLUSION: IHP treatment resulted in superior ORR, hPFS, and PFS compared with best alternative care in previously untreated patients with isolated liver metastases from primary uveal melanoma.
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