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Sökning: WFRF:(Axelsson Josefine)

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1.
  • Axelsson, Inge, 1947-, et al. (författare)
  • Kriminalisera kärnvapen
  • 2017
  • Ingår i: Hållbarhetens många ansikten. - Sundsvall : Mid Sweden University. - 9789188527370 ; , s. 102-107
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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2.
  • Axelsson, Josefine, et al. (författare)
  • A Precipitation Isotopic Response in 2014-2015 to Moisture Transport Changes in the Central Himalayas
  • 2023
  • Ingår i: Journal of Geophysical Research - Atmospheres. - 2169-897X .- 2169-8996. ; 128:13
  • Tidskriftsartikel (refereegranskat)abstract
    • The impact of moisture transport and sources on precipitation stable isotopes (d(18)O and d-excess) in the central Himalayas are crucial to understanding the climatic archives. However, this is still unclear due to the lack of in-situ observations. Here we present measurements of stable isotopes in precipitation at two stations (Yadong and Pali) in the central Himalayas during 2014-2015. Combined with simulations from the dispersion model FLEXPART, we investigate effects on precipitation stable isotopes related to changes in moisture sources and convections in the region, and possible influence by El Nino. Our results suggest that the moisture supplies related to evaporation over northeastern India and moisture losses related to convective activities over the Bay of Bengal (BoB) and Bangladesh region play important roles in changes in d(18)O and d-excess in precipitation in the Yadong Valley. Outgoing longwave radiation and moisture flux divergence analysis further confirm that the contribution from continental evaporation dominates the moisture supply in the central Himalayas with a lesser contribution from convection over the BoB during the 2015 monsoon season compared with 2014. A change in the altitude effect is observed in 2015, which is more significant than the temperature and precipitation amount effect during the observation period. These findings provide valuable insights into climatic interpretations of paleo-isotopic archives with an isotopic response to changes in moisture transport to the central Himalayas.
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3.
  • Axelsson, Josefine, 1992- (författare)
  • Interglacial climates in proxies and models : Utilizing sampled oxygen isotopes and model simulations to understand past Indian summer monsoon variability
  • 2024
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • The study of Earth's climate system, including the mechanisms driving monsoon systems, is a key area of research within environmental sciences. Monsoons, vital for billions of people, are complex atmospheric phenomena influenced by various global factors, including orbital changes and natural climate variability. Among monsoon systems, the Indian summer Monsoon (ISM) is of particular interest due to its significant impact on the South Asian climate, agriculture, and water resources. Despite extensive study, comprehending the ISM's historical variability and its future implications remains a challenge. Utilizing natural archives like speleothems, along with stable water isotopes from precipitation and advanced climate model simulations, this thesis aims to decipher the ISM's responses to natural forcings across key interglacial periods—the Last Interglacial and the Holocene.Our findings indicate that the ISM's strength is critically influenced by slight variations in orbital configurations, leading to significant shifts in monsoon patterns. Our research also highlights the dual influence of local geographical features and distant atmospheric conditions on the ISM's annual variability. Most notably, we observed discrepancies between δ18O values obtained from isotope-enabled climate models and those derived from speleothems. This insight indicates that the models need refinement to accurately mirror the complexities observed in the proxy records and that the uncertainty parameter in speleothem records needs to be improved.The alignment between proxy and model data is crucial for a more accurate reconstruction of past climates and for enhancing the predictive capabilities of future monsoon behavior under changing climatic conditions. By advancing our knowledge of the ISM's past, we are better equipped to anticipate its future. To achieve that, this thesis stresses the importance of bridging the gap between proxy data insights and climate model simulations. This would not only enrich our historical climate knowledge but also inform future climate projections, highlighting the indispensable role of interdisciplinary research in climate science challenges.
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4.
  • Bühler, Janica C., et al. (författare)
  • Investigating stable oxygen and carbon isotopic variability in speleothem records over the last millennium using multiple isotope-enabled climate models
  • 2022
  • Ingår i: Climate of the Past. - : Copernicus GmbH. - 1814-9324 .- 1814-9332. ; 18:7, s. 1625-1654
  • Tidskriftsartikel (refereegranskat)abstract
    • The incorporation of water isotopologues into the hydrology of general circulation models (GCMs) facilitates the comparison between modeled and measured proxy data in paleoclimate archives. However, the variability and drivers of measured and modeled water isotopologues, as well as the diversity of their representation in different models, are not well constrained. Improving our understanding of this variability in past and present climates will help to better constrain future climate change projections and decrease their range of uncertainty. Speleothems are a precisely datable terrestrial paleoclimate archives and provide well-preserved (semi-)continuous multivariate isotope time series in the lower latitudes and mid-latitudes and are therefore well suited to assess climate and isotope variability on decadal and longer timescales. However, the relationships of speleothem oxygen and carbon isotopes to climate variables are influenced by site-specific parameters, and their comparison to GCMs is not always straightforward.Here we compare speleothem oxygen and carbon isotopic signatures from the Speleothem Isotopes Synthesis and Analysis database version 2 (SISALv2) to the output of five different water-isotope-enabled GCMs (ECHAM5-wiso, GISS-E2-R, iCESM, iHadCM3, and isoGSM) over the last millennium (850–1850 CE). We systematically evaluate differences and commonalities between the standardized model simulation outputs. The goal is to distinguish climatic drivers of variability for modeled isotopes and compare them to those of measured isotopes.We find strong regional differences in the oxygen isotope signatures between models that can partly be attributed to differences in modeled surface temperature. At low latitudes, precipitation amount is the dominant driver for stable water isotope variability; however, at cave locations the agreement between modeled temperature variability is higher than for precipitation variability. While modeled isotopic signatures at cave locations exhibited extreme events coinciding with changes in volcanic and solar forcing, such fingerprints are not apparent in the speleothem isotopes. This may be attributed to the lower temporal resolution of speleothem records compared to the events that are to be detected. Using spectral analysis, we can show that all models underestimate decadal and longer variability compared to speleothems (albeit to varying extents).We found that no model excels in all analyzed comparisons, although some perform better than the others in either mean or variability. Therefore, we advise a multi-model approach whenever comparing proxy data to modeled data. Considering karst and cave internal processes, e.g., through isotope-enabled karst models, may alter the variability in speleothem isotopes and play an important role in determining the most appropriate model. By exploring new ways of analyzing the relationship between the oxygen and carbon isotopes, their variability, and co-variability across timescales, we provide methods that may serve as a baseline for future studies with different models using, e.g., different isotopes, different climate archives, or different time periods.
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5.
  • Chen, Kaiqi, et al. (författare)
  • EC-Earth Simulations Reveal Enhanced Inter-Hemispheric Thermal Contrast During the Last Interglacial Further Intensified the Indian Monsoon
  • 2022
  • Ingår i: Geophysical Research Letters. - 0094-8276 .- 1944-8007. ; 49:6
  • Tidskriftsartikel (refereegranskat)abstract
    • Paleoclimate proxy data indicate a stronger Indian summer monsoon (ISM) during the Last Interglacial (LIG) than in the present day. This is largely attributed to orbital forcing induced high seasonal and latitudinal insolation anomalies in the Northern Hemisphere during LIG. According to the general circulation model EC-Earth3, the simulated ISM rainfall is increased by approximately 28% during the LIG compared to the pre-industrial period as a result of the orbital forcing and the amplified land-sea contrast due to both local and remote ocean feedbacks. Although the LIG is often portrayed as a potential analogue of future warmer climates, our study suggests that the enhanced inter-hemispheric thermal gradient during the LIG strengthened the ISM, in opposition to the observed weakening of ISM under present-day warming.
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6.
  • Colombe, Soledad, et al. (författare)
  • Monitoring the progress towards the elimination of hepatitis B and C in Sweden : estimation of core indicators for 2015 and 2018
  • 2022
  • Ingår i: BMC Infectious Diseases. - : BioMed Central (BMC). - 1471-2334. ; 22:1
  • Tidskriftsartikel (refereegranskat)abstract
    • INTRODUCTION: To monitor Sweden's progress towards the WHO goal of eliminating viral hepatitis, we estimated the prevalence, notification rate, and liver-related morbidity and mortality for diagnosed hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in 2015 and 2018.METHODS: We identified cases of hepatitis B and C within the National System for Notifiable Diseases and obtained data on treatment and whether the case was deceased or not. We calculated prevalence, notification rates per 100,000, and proportion of newly diagnosed cases of hepatitis with liver disease at the time of diagnosis, and proportion of all deceased cases who died from liver disease. We calculated Poisson 95% confidence intervals (CIs) around the notification rates and Wilson 95% CIs around prevalence and mortality estimates.RESULTS: In 2015 and 2018, the prevalence of diagnosed HBV infections was 0.20% [95% CI: 0.19-0.20] and 0.21% [0.20-0.21]. Notification rates per 100,000 for HBV infections were 13.02 [12.32-13.76] and 7.71 [7.18-8.27]. HBV liver-related morbidity was 2.65% [1.90-3.68] and 2.16% [1.35-3.43]. HBV liver-related mortality was 20.00% [14.81-26.44] and 17.95% [13.20-23.94]. In 2015 and 2018, the prevalence of diagnosed HCV-infections was 0.24% [0.24-0.25] and 0.18% [0.18-0.19]. Notification rates per 100,000 for HCV infections were 15.92 [15.14-16.73] and 13.05 [12.36-13.77]. HCV liver-related morbidity was 8.14% [6.89-9.60] and 3.90% [2.99-5.08]. HCV liver-related mortality was 27.08% [24.54-29.77] and 26.90% [24.12-29.88].CONCLUSIONS: All indicators decreased or remained stable between 2015 and 2018, indicating progress in the elimination of viral hepatitis, especially for HCV infection.
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7.
  • Glad, Wiktoria, 1973-, et al. (författare)
  • Hot (water) topics : The formation of an energy issue at home
  • 2017
  • Ingår i: eceee 2017 Summer Study on energy efficiency. - 9789198387803 - 9789198387810 ; , s. 2069-2074
  • Konferensbidrag (refereegranskat)abstract
    • Domestic use of hot water has been identified as an urgent energy issue to address. In this paper, results from focus group interviews, with both residents and staff members, are presented. Results show that hot tap water use is differently shaped depending on whether you are a resident or a staff member. One thing in common was that in the focus groups it was difficult to separate hot tap water use from water use in general. Hot tap water use was not distinguished from use of cold tap water. To explore the issue further, the research on hot water was taken to residents’ homes and through more in-depth qualitative methods by an artist a formation process was started. Residents started to share more detailed stories about how they lived their everyday life in kitchens and bathrooms. These stories contain childhood memories and how past experience has shaped their water use and consequently their energy use patterns. The formation of this topic continued and in the artist’s interpretation of the data, three different artefacts became important: the sink, tub and toilet. These artefacts were placed in a river in the centre of a city as part of an audio walk with voices from the residents talking about their use of water. The exhibition was available during summer 2016 and the audio walk with the voices are planned to be reused and part of an exhibition in 2017.
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8.
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9.
  • Lin, Fangyuan, 1996-, et al. (författare)
  • Seasonal to decadal variations of precipitation oxygen isotopes in northern China linked to the moisture source
  • 2024
  • Ingår i: npj Climate and Atmospheric Science. - 2397-3722. ; 7
  • Tidskriftsartikel (refereegranskat)abstract
    • A precise characterization of moisture source and transport dynamics over the inland margins of monsoonal China is crucial for understanding the climatic significance of precipitation oxygen isotope (δ18Op) variability preserved in the regional proxy archives. Here, we use a general circulation model with an embedded water-tagging module to quantify the role of moisture dynamics on the seasonal to decadal variations of δ18Op in northern China. Our data indicate that during the non-monsoon season, the δ18Op variability is dominated by the temperature effect. Conversely, in the summer monsoon season, the moisture contributions from the low-latitude land areas (LLA), the Pacific Ocean (PO), and the North Indian Ocean (NIO) override the temperature effect and influence the summer δ18Op. Intensified upstream convection along the NIO moisture transport pathway results in a more negative summer δ18Op compared to moisture transported from the PO and LLA regions. Our analysis shows a decadal shift in summer δ18Op around the mid-1980s, marking changes in the relative contribution of oceanic moisture from PO and NIO in response to changes in the atmospheric circulation patterns influenced by the Pacific Decadal Oscillation. We suggest that such decadal-scale δ18Op variability can be recorded in the natural archives from the region, which can provide valuable insights into understanding past climate variability.
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10.
  • Nilsson, Erik, et al. (författare)
  • The grade of individual prostate cancer lesions predicted by magnetic resonance imaging and positron emission tomography
  • 2023
  • Ingår i: Communications Medicine. - : Springer Nature. - 2730-664X. ; 3:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Multiparametric magnetic resonance imaging (mpMRI) and positron emission tomography (PET) are widely used for the management of prostate cancer (PCa). However, how these modalities complement each other in PCa risk stratification is still largely unknown. We aim to provide insights into the potential of mpMRI and PET for PCa risk stratification.Methods: We analyzed data from 55 consecutive patients with elevated prostate-specific antigen and biopsy-proven PCa enrolled in a prospective study between December 2016 and December 2019. [68Ga]PSMA-11 PET (PSMA-PET), [11C]Acetate PET (Acetate-PET) and mpMRI were co-registered with whole-mount histopathology. Lower- and higher-grade lesions were defined by International Society of Urological Pathology (ISUP) grade groups (IGG). We used PET and mpMRI data to differentiate between grades in two cases: IGG 3 vs. IGG 2 (case 1) and IGG ≥ 3 vs. IGG ≤ 2 (case 2). The performance was evaluated by receiver operating characteristic (ROC) analysis.Results: We find that the maximum standardized uptake value (SUVmax) for PSMA-PET achieves the highest area under the ROC curve (AUC), with AUCs of 0.72 (case 1) and 0.79 (case 2). Combining the volume transfer constant, apparent diffusion coefficient and T2-weighted images (each normalized to non-malignant prostatic tissue) results in AUCs of 0.70 (case 1) and 0.70 (case 2). Adding PSMA-SUVmax increases the AUCs by 0.09 (p < 0.01) and 0.12 (p < 0.01), respectively.Conclusions: By co-registering whole-mount histopathology and in-vivo imaging we show that mpMRI and PET can distinguish between lower- and higher-grade prostate cancer, using partially discriminative cut-off values.
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