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Sökning: WFRF:(Baldwin Timothy)

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1.
  • Baldwin, Timothy, et al. (författare)
  • Universals of Linguistic Idiosyncrasy in Multilingual Computational Linguistics
  • 2021
  • Ingår i: Dagstuhl Reports. - Dagstuhl. - 2192-5283. ; 11:7, s. 89-138
  • Tidskriftsartikel (refereegranskat)abstract
    • Computational linguistics builds models that can usefully process and produce language and thatcan increase our understanding of linguistic phenomena. From the computational perspective,language data are particularly challenging notably due to their variable degree of idiosyncrasy(unexpected properties shared by few peer objects), and the pervasiveness of non-compositionalphenomena such as multiword expressions (whose meaning cannot be straightforwardly deducedfrom the meanings of their components, e.g. red tape, by and large, to pay a visit and to pullone’s leg) and constructions (conventional associations of forms and meanings). Additionally, ifmodels and methods are to be consistent and valid across languages, they have to face specificitiesinherent either to particular languages, or to various linguistic traditions.These challenges were addressed by the Dagstuhl Seminar 21351 entitled “Universals ofLinguistic Idiosyncrasy in Multilingual Computational Linguistics”, which took place on 30-31 August 2021. Its main goal was to create synergies between three distinct though partlyoverlapping communities: experts in typology, in cross-lingual morphosyntactic annotation and inmultiword expressions. This report documents the program and the outcomes of the seminar. Wepresent the executive summary of the event, reports from the 3 Working Groups and abstracts ofindividual talks and open problems presented by the participants.
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2.
  • Clark, Andrew G., et al. (författare)
  • Evolution of genes and genomes on the Drosophila phylogeny
  • 2007
  • Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 450:7167, s. 203-218
  • Tidskriftsartikel (refereegranskat)abstract
    • Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of 12 Drosophila species, ten of which are presented here for the first time (sechellia, simulans, yakuba, erecta, ananassae, persimilis, willistoni, mojavensis, virilis and grimshawi), illustrate how rates and patterns of sequence divergence across taxa can illuminate evolutionary processes on a genomic scale. These genome sequences augment the formidable genetic tools that have made Drosophila melanogaster a pre-eminent model for animal genetics, and will further catalyse fundamental research on mechanisms of development, cell biology, genetics, disease, neurobiology, behaviour, physiology and evolution. Despite remarkable similarities among these Drosophila species, we identified many putatively non-neutral changes in protein-coding genes, non-coding RNA genes, and cis-regulatory regions. These may prove to underlie differences in the ecology and behaviour of these diverse species.
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3.
  • Elsik, Christine G., et al. (författare)
  • The Genome Sequence of Taurine Cattle : A Window to Ruminant Biology and Evolution
  • 2009
  • Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 324:5926, s. 522-528
  • Tidskriftsartikel (refereegranskat)abstract
    • To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set of 14,345 orthologs shared among seven mammalian species of which 1217 are absent or undetected in noneutherian (marsupial or monotreme) genomes. Cattle-specific evolutionary breakpoint regions in chromosomes have a higher density of segmental duplications, enrichment of repetitive elements, and species-specific variations in genes associated with lactation and immune responsiveness. Genes involved in metabolism are generally highly conserved, although five metabolic genes are deleted or extensively diverged from their human orthologs. The cattle genome sequence thus provides a resource for understanding mammalian evolution and accelerating livestock genetic improvement for milk and meat production.
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4.
  • Feng, Shaohong, et al. (författare)
  • Dense sampling of bird diversity increases power of comparative genomics
  • 2020
  • Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 587:7833
  • Tidskriftsartikel (refereegranskat)abstract
    • Whole-genome sequencing projects are increasingly populating the tree of life and characterizing biodiversity(1-4). Sparse taxon sampling has previously been proposed to confound phylogenetic inference(5), and captures only a fraction of the genomic diversity. Here we report a substantial step towards the dense representation of avian phylogenetic and molecular diversity, by analysing 363 genomes from 92.4% of bird families-including 267 newly sequenced genomes produced for phase II of the Bird 10,000 Genomes (B10K) Project. We use this comparative genome dataset in combination with a pipeline that leverages a reference-free whole-genome alignment to identify orthologous regions in greater numbers than has previously been possible and to recognize genomic novelties in particular bird lineages. The densely sampled alignment provides a single-base-pair map of selection, has more than doubled the fraction of bases that are confidently predicted to be under conservation and reveals extensive patterns of weak selection in predominantly non-coding DNA. Our results demonstrate that increasing the diversity of genomes used in comparative studies can reveal more shared and lineage-specific variation, and improve the investigation of genomic characteristics. We anticipate that this genomic resource will offer new perspectives on evolutionary processes in cross-species comparative analyses and assist in efforts to conserve species. A dataset of the genomes of 363 species from the Bird 10,000 Genomes Project shows increased power to detect shared and lineage-specific variation, demonstrating the importance of phylogenetically diverse taxon sampling in whole-genome sequencing.
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5.
  • Frohlich, Miguel F., et al. (författare)
  • Legal barriers to adaptive coastal management at a coastal erosion hotspot in Florianópolis, Brazil
  • 2021
  • Ingår i: Marine Policy. - : Elsevier. - 0308-597X .- 1872-9460. ; 127
  • Tidskriftsartikel (refereegranskat)abstract
    • Adaptive management has long been promulgated as an appropriate approach to address the complexity and dynamics of coastal social-ecological systems. However, examples of successful implementation of this approach are still scarce. Law may be a factor hindering adaptive management, particularly when legal provisions are too rigid to enable change. Drawing on the management experience of Armaca similar to o Beach (a coastal erosion hotspot in the Municipality of Florian ' opolis, State of Santa Catarina, Brazil), this paper: (a) analyses how adaptive management has been used for coastal management in the selected study area and its applicable legal framework; and (b) identifies legal barriers to adaptive coastal management. Document analysis and semi-structured interviews with 27 participants were undertaken. An inductive thematic coding strategy was adopted to analyse interview data. Interpretation of results shows that coastal management in Florian ' opolis is yet to follow the structured and iterative learning process of adaptive management. Vague, imprecise, and generic legal provisions have contributed to reactive coastal management. In the context of open-ended legislation, government entities have used their legal discretion to avoid making coastal management plans, and short-term defence strategies to manage coastal erosion have proliferated in response to crisis situations. The paper highlights the importance of seeking the right balance between legal certainty and legal flexibility, providing an entry point to further research and legal reform discussions in the field of adaptive coastal management.
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6.
  • Frohlich, Miguel F., et al. (författare)
  • Towards adaptive coastal management : Lessons from a "legal storm" in Byron Shire, Australia
  • 2019
  • Ingår i: Ocean and Coastal Management. - : ELSEVIER SCI LTD. - 0964-5691 .- 1873-524X. ; 179
  • Tidskriftsartikel (refereegranskat)abstract
    • Adaptive management has been advocated as an appropriate approach for the management of social-ecological systems, although its implementation has proven to be a challenge. Legal systems can hinder or facilitate adaptive management. Focusing on legal arrangements, this article explores how adaptive management can be better operationalised in the context of coastal management. Byron Shire, a local government area in New South Wales, Australia, was selected as a case study where we: (a) analysed how the concept of adaptive management has emerged within the evolution of coastal management and its applicable legal framework, and (b) identified juridical constraints to adaptive coastal management. Qualitative methods were used for the analysis of relevant documents and semi-structured interviews with 23 key informants. The results show that a distorted version of adaptive management has been adopted in Byron Shire's draft coastal management plans, which fails to adhere to the formal, structured, and iterative process of adaptive management. A legacy created by the legal effects of past decisions affecting coastal management has led to a path dependency towards protective measures to manage coastal erosion, constraining other management options, particularly managed realignment strategies. Failure to address juridical constraints in the early stages of the adaptive management process can result in stakeholder conflict and litigation. Overlitigation harms adaptive coastal management by pushing the decision-making process away from the pathway offered by the legal framework for preparing and implementing coastal management plans. After recent legislative coastal reform at the state level, there is momentum for the Byron Shire Council to refocus its adaptive management approach. However, overcoming existing juridical constraints will require adaptive governance, in which all levels of government must work collaboratively with the affected stakeholders in the design and implementation of the adaptive management process.
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7.
  • Frohlich, Miguel, et al. (författare)
  • Towards adaptive coastal management law : Lessons from Australia and Brazil
  • 2022
  • Ingår i: Ocean and Coastal Management. - : Elsevier. - 0964-5691 .- 1873-524X. ; 219
  • Tidskriftsartikel (refereegranskat)abstract
    • Although adaptive management has been advocated for dealing with the complexity and dynamics of social ecological systems for more than 40 years, successful outcomes in practice have been limited. Among the efforts to overcome this implementation gap, there has been a growing interest in understanding the role of law in adaptive management. In this article, we provide an analysis of adaptive management in two jurisdictions struggling with coastal erosion in the context of their legal arrangements for coastal management: (i) Byron Shire, a local government area in the State of New South Wales, Australia; and (ii) Florian acute accent opolis, a municipality in the State of Santa Catarina, Brazil. Methods included document analysis and inductive thematic coding of 50 semi-structured interviews with key informants from four different stakeholder groups. Our results indicate that both legal certainty and legal flexibility are relevant for adaptive management success. Three directions towards coupling adaptive coastal management with law are suggested: (i) to incorporate adaptive management into coastal management legislation; (ii) to address legal path dependencies that cause maladaptation; and (iii) to integrate adaptive coastal management and adaptive coastal governance through adaptive coastal management law. Our suggestions contribute to improved knowledge on adaptive coastal management law by emphasising the need for an optimal balance between legal flexibility and legal certainty, which represents an avenue for further research and policy development beyond the jurisdictions analysed.
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8.
  • Grigonyte, Gintare, et al. (författare)
  • Automatic Detection of Multilingual Dictionaries on the Web
  • 2014
  • Ingår i: Proceedings of the 52nd Annual Meeting of the Association for Computational Linguistics (Short Papers). - : Association for Computational Linguistics. ; , s. 93-98
  • Konferensbidrag (refereegranskat)
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9.
  • Hochberg, Georg K A, et al. (författare)
  • Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions.
  • 2018
  • Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 359:6378, s. 930-935
  • Tidskriftsartikel (refereegranskat)abstract
    • Oligomeric proteins assemble with exceptional selectivity, even in the presence of closely related proteins, to perform their cellular roles. We show that most proteins related by gene duplication of an oligomeric ancestor have evolved to avoid hetero-oligomerization and that this correlates with their acquisition of distinct functions. We report how coassembly is avoided by two oligomeric small heat-shock protein paralogs. A hierarchy of assembly, involving intermediates that are populated only fleetingly at equilibrium, ensures selective oligomerization. Conformational flexibility at noninterfacial regions in the monomers prevents coassembly, allowing interfaces to remain largely conserved. Homomeric oligomers must overcome the entropic benefit of coassembly and, accordingly, homomeric paralogs comprise fewer subunits than homomers that have no paralogs.
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10.
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