| 1. |
- Appendino, G, et al.
(författare)
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Antibacterial galloylated alkylphloroglucinol glucosides from myrtle (Myrtus communis)
- 2006
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Ingår i: Journal of Natural Products. - : American Chemical Society (ACS). - 0163-3864 .- 1520-6025. ; 69:2, s. 251-254
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Tidskriftsartikel (refereegranskat)abstract
- An investigation of the polar glycosidic fraction from the leaves of myrtle afforded four galloylated nonprenylated phloroglucinol glucosides (3a-d) related to the endoperoxide hormone G3 (4) in terms of structure and biogenesis. Despite their close similarity, significant antibacterial activity was shown only by one of these compounds (3b, gallomyrtucommulone B), while the G3 hormone (4) was inactive.
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| 2. |
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| 3. |
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| 4. |
- Appendino, G, et al.
(författare)
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Oligomeric acylphloroglucinols from myrtle (Myrtus communis)
- 2002
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Ingår i: Journal of Natural Products. - : American Chemical Society (ACS). - 0163-3864 .- 1520-6025. ; 65:3, s. 334-338
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Tidskriftsartikel (refereegranskat)abstract
- The dimeric nonprenylated acylphloroglucinol semimyrtucommulone (6) was obtained from the leaves of. myrtle (Myrtus communis) as a 2:1 mixture of two rotamers. The known trimeric phloroglucinol myrtucommulone A (1) was also isolated and characterized spectroscopically as a silylated cyclized derivative (5). Myrtucommulone A showed significant antibacterial activity against multidrug-resistant (MDR) clinically relevant bacteria, while semimyrtucommulone was less active.
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| 5. |
- Appendino, G, et al.
(författare)
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SERCA-inhibiting activity of C-19 terpenolides from Thapsia garganica and their possible biogenesis
- 2005
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Ingår i: Journal of Natural Products. - : American Chemical Society (ACS). - 0163-3864 .- 1520-6025. ; 68:8, s. 1213-1217
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Tidskriftsartikel (refereegranskat)abstract
- An investigation of Thapsia garganica afforded a series of tetracyclic C-19 dilactones, whose production was dependent on the time and location of the collection. These unusual tetrahomosesquiterpenoids are presumably biosynthesized via a carbon dioxide-triggered electrophilic polyolefin cyclization. Despite the structural differences with thapsigargin, these compounds showed SERCA-inhibiting properties.
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| 6. |
- Pistelli, L, et al.
(författare)
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Pterocarpans from Bituminaria bituminosa and Bituminaria morisiana.
- 2003
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Ingår i: Phytochemistry. - 0031-9422. ; 64:2, s. 595-598
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Tidskriftsartikel (refereegranskat)abstract
- The aerial parts of Mediterranean papilionaceous plants Bituminaria morisiana and B. bituminosa afforded, along with known phenolics, the prenylated pterocarpans bitucarpin A and B, whose structure was elucidated by spectroscopic techniques. A known isoflavonoid (8-prenyldaidzein) was also obtained for the first time as a genuine plant constituent. The accumulation of pterocarpans at the expense of biogenetically more primitive shikimate metabolites like furanocoumarins or isoflavonoids supports the inclusion of this plant, once part of the genus Psoralea, into the distinct genus Bituminaria.
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