| 1. |
- Aarestrup, FM, et al.
(författare)
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Towards a European health research and innovation cloud (HRIC)
- 2020
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Ingår i: Genome medicine. - : Springer Science and Business Media LLC. - 1756-994X. ; 12:1, s. 18-
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Tidskriftsartikel (refereegranskat)abstract
- The European Union (EU) initiative on the Digital Transformation of Health and Care (Digicare) aims to provide the conditions necessary for building a secure, flexible, and decentralized digital health infrastructure. Creating a European Health Research and Innovation Cloud (HRIC) within this environment should enable data sharing and analysis for health research across the EU, in compliance with data protection legislation while preserving the full trust of the participants. Such a HRIC should learn from and build on existing data infrastructures, integrate best practices, and focus on the concrete needs of the community in terms of technologies, governance, management, regulation, and ethics requirements. Here, we describe the vision and expected benefits of digital data sharing in health research activities and present a roadmap that fosters the opportunities while answering the challenges of implementing a HRIC. For this, we put forward five specific recommendations and action points to ensure that a European HRIC: i) is built on established standards and guidelines, providing cloud technologies through an open and decentralized infrastructure; ii) is developed and certified to the highest standards of interoperability and data security that can be trusted by all stakeholders; iii) is supported by a robust ethical and legal framework that is compliant with the EU General Data Protection Regulation (GDPR); iv) establishes a proper environment for the training of new generations of data and medical scientists; and v) stimulates research and innovation in transnational collaborations through public and private initiatives and partnerships funded by the EU through Horizon 2020 and Horizon Europe.
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| 2. |
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| 3. |
- Auffray, C., et al.
(författare)
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COVID-19 and beyond : a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight
- 2020
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Ingår i: F1000 Research. - : F1000 Research Ltd. - 2046-1402. ; 9, s. 1130-18
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Tidskriftsartikel (refereegranskat)abstract
- Background: Severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) belongs to a subgroup of coronaviruses rampant in bats for centuries. It caused the coronavirus disease 2019 (COVID-19) pandemic. Most patients recover, but a minority of severe cases experience acute respiratory distress or an inflammatory storm devastating many organs that can lead to patient death. The spread of SARS-CoV-2 was facilitated by the increasing intensity of air travel, urban congestion and human contact during the past decades. Until therapies and vaccines are available, tests for virus exposure, confinement and distancing measures have helped curb the pandemic. Vision: The COVID-19 pandemic calls for safeguards and remediation measures through a systemic response. Self-organizing initiatives by scientists and citizens are developing an advanced collective intelligence response to the coronavirus crisis. Their integration forms Olympiads of Solidarity and Health. Their ability to optimize our response to COVID-19 could serve as a model to trigger a global metamorphosis of our societies with far-reaching consequences for attacking fundamental challenges facing humanity in the 21st century. Mission: For COVID-19 and these other challenges, there is no alternative but action. Meeting in Paris in 2003, we set out to "rethink research to understand life and improve health." We have formed an international coalition of academia and industry ecosystems taking a systems medicine approach to understanding COVID-19 by thoroughly characterizing viruses, patients and populations during the pandemic, using openly shared tools. All results will be publicly available with no initial claims for intellectual property rights. This World Alliance for Health and Wellbeing will catalyze the creation of medical and health products such as diagnostic tests, drugs and vaccines that become common goods accessible to all, while seeking further alliances with civil society to bridge with socio-ecological and technological approaches that characterise urban systems, for a collective response to future health emergencies.
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| 6. |
- Abramovitz, T, et al.
(författare)
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MONA LISA : Deep seismic investigations of the lithosphere in the southeastern North Sea
- 1997
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Ingår i: TECTONOPHYSICS. - : ELSEVIER SCIENCE BV. - 0040-1951. ; 269:1-2, s. 1-19
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- The MONA LISA collaborative project has collected 1112 km of seismic normal-incidence reflection data (recorded to 26 s) and wide-angle data from 26 onshore and 2 offshore locations along 4 profiles in the southeastern North Sea. The seismic data clearly
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| 7. |
- Cappellin, C., et al.
(författare)
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Design and analysis of a reflector antenna system based on doubly curved Circular Polarization Selective Surfaces
- 2016
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Ingår i: 2016 10th European Conference on Antennas and Propagation, EuCAP 2016. - 9788890701863
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Konferensbidrag (refereegranskat)abstract
- This paper discusses the design and analysis of a reflector antenna system combining two doubly-curved Circular Polarization Selective Surfaces to provide a functionality equivalent to that of a dual gridded reflector but in circular polarization. The key feature of this design is to use a non-resonant CPSS design to avoid the bandwidth limitation of most CPSS designs previously discussed in the literature. A specific design at Ku-band is investigated and promising results are demonstrated, providing a cross-polarization discrimination higher than 25 dB over the full band.
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| 8. |
- England, RW, et al.
(författare)
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Closure of the Tornquist sea: Constraints from MONA LISA deep seismic reflection data
- 1997
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Ingår i: GEOLOGY. - : GEOLOGICAL SOC AMERICA. - 0091-7613. ; 25:12, s. 1071-1074
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Deep seismic reflection profiles west of Denmark across the suture between Baltica and Eastern Avalonia reveal weak, southward-dipping reflectors within the crystalline basement. These reflectors are interpreted as thrusts resulting from emplacement of Ea
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| 9. |
- Ericsson, A., et al.
(författare)
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A Contoured-Beam Reflector Satellite Antenna Using Two Doubly Curved Circular Polarization Selective Surfaces
- 2021
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Ingår i: IEEE Transactions on Antennas and Propagation. - 0018-926X. ; 69:2, s. 658-671
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Tidskriftsartikel (refereegranskat)abstract
- We present a reflector antenna system using a circular polarization selective surface (CPSS) to realize a circular polarization (CP) equivalent to the widely used linear polarization (LP) gridded or dual-gridded reflector (DGR). The CPSS is realized by a multilayer stack of non-resonant anisotropic meander line surfaces, achieving a very wide bandwidth. The CPSS reflection and transmission dyadics are computed using full-wave simulations for all angles of incidence and design frequencies applicable, and the doubly curved reflector surface shapes are optimized in the TICRA POS software. The data are input to the TICRA Tools software framework for antenna-system level RF simulations. A planar CPSS sample was first manufactured and tested to demonstrate the adequacy of the selected multilayer design. A doubly curved reflector demonstrator based on the same technology and with a projected aperture of 750 mm was then designed, manufactured, and tested at Ku-band. While promising, the experimental results emphasize the difficulty of producing an electrically large multilayer doubly curved surface with RF performance equivalent to the original flat design and recommendations are provided to improve further the implementation of the proposed design.
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| 10. |
- Hobbs, R. W., et al.
(författare)
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Integrated seismic studies of the Baltic shield using data in the Gulf of Bothnia region
- 1993
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Ingår i: Geophysical Journal International. - 0956-540X .- 1365-246X. ; 112:3, s. 305-324
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Tidskriftsartikel (refereegranskat)abstract
- In the autumn of 1989 a co-operative experiment involving 12 research institutions in northwestern Europe collected 2268 km of deep seismic reflection profiles in the Gulf of Bothnia and the Baltic Sea. the 121 litre airgun array used for this profiling was also recorded by 62 muiticomponent land stations to provide coincident refraction surveys, fan-spreads, and 3-D seismic coverage of much of the Gulf of Bothnia. We thus have potentially both high-resolution impedance contrast images as well as more regional 3-D velocity models in both P- and S-waves. In the Bothnian Bay a south-dipping, non-reflective zone coincides with the conductive Archaean-Proterozoic boundary onshore in Finland. Between the Bothnian Bay and Bothnian Sea observed reflectivity geometries and velocity models at Moho depths suggest structures inherited from a 1.9Ga subduction zone; the upper crust here appears to have anomalously low velocity. Within the Bothnian Sea, reflectivity varies considerably beneath the metasedimentary/granitoid rocks of the Central Svecofennian Province (CSP) and the surrounding metavolcanic-arc rocks. Numerous dipping reflectors appear throughout the metavolcanic crust, whereas the CSP has little reflectivity. Wide-angle reflections indicate that the metasedimentary crust of the Bothnian Basin is 10 km thicker than the neighbouring Svecofennian subprovinces. Near the Åland archipelago Rapakivi granite plutons exhibit bright reflections, a contrast to the usual non-reflective plutons elsewhere in western Europe. Additional dipping reflections deep in the crust of this area may support models of rifting and crustal thinning during emplacement of the 1.70-1.54 Ga Rapakivi granites. Coeval gabbroic/anorthositic magmatism may explain the high reflectivity and high velocity of these plutons. the c. 1.25 Ga mafic sills and feeder dykes of the Central Scandinavian Dolerite Group also produce clear reflections on both near- and far-offset seismic sections. Continued modelling will produce better velocity models of the crust and better constrained contour maps of crustal thickness in this part of the Baltic shield.
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