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Träfflista för sökning "WFRF:(Barnes Colin) "

Sökning: WFRF:(Barnes Colin)

  • Resultat 1-10 av 20
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1.
  • Sumaila, U. Rashid, et al. (författare)
  • WTO must ban harmful fisheries subsidies
  • 2021
  • Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 374:6567, s. 544-544
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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2.
  • Ades, M., et al. (författare)
  • Global Climate : in State of the climate in 2019
  • 2020
  • Ingår i: Bulletin of The American Meteorological Society - (BAMS). - : American Meteorological Society. - 0003-0007 .- 1520-0477. ; 101:8, s. S17-S127
  • Tidskriftsartikel (refereegranskat)
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3.
  • Ades, M., et al. (författare)
  • GLOBAL CLIMATE
  • 2020
  • Ingår i: BULLETIN OF THE AMERICAN METEOROLOGICAL SOCIETY. - 0003-0007 .- 1520-0477. ; 101:8, s. S17-S127
  • Tidskriftsartikel (refereegranskat)
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  • Barnes, Colin, et al. (författare)
  • Disability, Politics and Poverty in a Majority World Context
  • 2010
  • Ingår i: Disability & Society. - London : Taylor & Francis. - 0968-7599 .- 1360-0508. ; 25:7, s. 771-782
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper argues that the spread of free market economics throughout the world has generated unprecedented inequalities within and between nation states. This has led to the systematic exclusion of people with perceived impairments from the mainstream of economic and community life in almost all societies, the generation of an international disabled people’s movement, and their demand for legal frameworks with which to address the multiple deprivations encountered by people viewed as ‘disabled’. It is argued that the poverty and exclusion encountered by disabled people and other oppressed groups in all societies will not be eliminated without fundamental structural change at the international level
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  • Barnes, Colin (författare)
  • Understanding Disability and the Importance of Design for All
  • 2011
  • Ingår i: Journal of Accessibility and Design for All. - : Fundación ONCE. - 2013-7087. ; 1:1, s. 55-80
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper will address recent debates surrounding the nature and cause of the complex process of disablement and their relevance to understanding calls for a universally accessible physical and cultural environment. It is divided into three main sections. The first part will explore changing perceptions of disability. Attention will centre on the traditional individualistic medical approach, the socio-political understanding or ‘social model of disability’ and the recent ‘biopsychosocial’ model of disability exemplified by the World Health Organisation’s International Classification of Functioning, Disability and Health. This will be followed by a discussion of the usefulness of the concept of ‘universal design’. The final section will discuss the significance of these developments in light of globalisation, associate economic, political and social crises, and the struggle for a fairer and just global society.
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8.
  • Erzurumluoglu, A. Mesut, et al. (författare)
  • Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci
  • 2020
  • Ingår i: Molecular Psychiatry. - : Nature Publishing Group. - 1359-4184 .- 1476-5578. ; 25:10, s. 2392-2409
  • Tidskriftsartikel (refereegranskat)abstract
    • Smoking is a major heritable and modifiable risk factor for many diseases, including cancer, common respiratory disorders and cardiovascular diseases. Fourteen genetic loci have previously been associated with smoking behaviour-related traits. We tested up to 235,116 single nucleotide variants (SNVs) on the exome-array for association with smoking initiation, cigarettes per day, pack-years, and smoking cessation in a fixed effects meta-analysis of up to 61 studies (up to 346,813 participants). In a subset of 112,811 participants, a further one million SNVs were also genotyped and tested for association with the four smoking behaviour traits. SNV-trait associations with P < 5 × 10-8 in either analysis were taken forward for replication in up to 275,596 independent participants from UK Biobank. Lastly, a meta-analysis of the discovery and replication studies was performed. Sixteen SNVs were associated with at least one of the smoking behaviour traits (P < 5 × 10-8) in the discovery samples. Ten novel SNVs, including rs12616219 near TMEM182, were followed-up and five of them (rs462779 in REV3L, rs12780116 in CNNM2, rs1190736 in GPR101, rs11539157 in PJA1, and rs12616219 near TMEM182) replicated at a Bonferroni significance threshold (P < 4.5 × 10-3) with consistent direction of effect. A further 35 SNVs were associated with smoking behaviour traits in the discovery plus replication meta-analysis (up to 622,409 participants) including a rare SNV, rs150493199, in CCDC141 and two low-frequency SNVs in CEP350 and HDGFRP2. Functional follow-up implied that decreased expression of REV3L may lower the probability of smoking initiation. The novel loci will facilitate understanding the genetic aetiology of smoking behaviour and may lead to the identification of potential drug targets for smoking prevention and/or cessation.
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9.
  • Evangelou, Evangelos, et al. (författare)
  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
  • 2018
  • Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 50:10, s. 1412-1425
  • Tidskriftsartikel (refereegranskat)abstract
    • High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1 million people of European ancestry. We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also highlight shared genetic architecture between blood pressure and lifestyle exposures. Our findings identify new biological pathways for blood pressure regulation with potential for improved cardiovascular disease prevention in the future.
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