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- Cousin, A., et al.
(författare)
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Compositions of coarse and fine particles in martian soils at gale: A window into the production of soils
- 2015
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Ingår i: Icarus. - : Elsevier BV. - 0019-1035 .- 1090-2643. ; 249, s. 22-42
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Tidskriftsartikel (refereegranskat)abstract
- The ChemCam instrument onboard the Curiosity rover provides for the first time an opportunity to study martian soils at a sub-millimeter resolution. In this work, we analyzed 24 soil targets probed by ChemCam during the first 250 sols on Mars. Using the depth profile capability of the ChemCam LIBS (Laser-Induced Breakdown Spectroscopy) technique, we found that 45% of the soils contained coarse grains (>500 μm). Three distinct clusters have been detected: Cluster 1 shows a low SiO2 content; Cluster 2 corresponds to coarse grains with a felsic composition, whereas Cluster 3 presents a typical basaltic composition. Coarse grains from Cluster 2 have been mostly observed exposed in the vicinity of the landing site, whereas coarse grains from Clusters 1 and 3 have been detected mostly buried, and were found all along the rover traverse. The possible origin of these coarse grains was investigated. Felsic (Cluster 2) coarse grains have the same origin as the felsic rocks encountered near the landing site, whereas the origin of the coarse grains from Clusters 1 and 3 seems to be more global. Fine-grained soils (particle size < laser beam diameter which is between 300 and 500 μm) show a homogeneous composition all along the traverse, different from the composition of the rocks encountered at Gale. Although they contain a certain amount of hydrated amorphous component depleted in SiO2, possibly present as a surface coating, their overall chemical homogeneity and their close-to-basaltic composition suggest limited, or isochemical alteration, and a limited interaction with liquid water. Fine particles and coarse grains from Cluster 1 have a similar composition, and the former could derive from weathering of the latter. Overall martian soils have a bulk composition between that of fine particles and coarse grains. This work shows that the ChemCam instrument provides a means to study the variability of soil composition at a scale not achievable by bulk chemical analyses.
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- Bidartondo, Martin, et al.
(författare)
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Preserving accuracy in GenBank
- 2008
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Ingår i: Science. ; 319:5870
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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- Blaise, M., et al.
(författare)
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CREATIVELY ATTENDING TO UNFINISHED BUSINESS, EVERYDAY SEXISMS, COVID-19, AND HIGHER EDUCATION : The #FEAS fake journal
- 2024
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Ingår i: The Routledge International Handbook of Transdisciplinary Feminist Research and Methodological Praxis. - : Taylor & Francis. - 9781003847601 - 9781032301297 ; , s. 380-382
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- COVID-19 amplified the everyday sexisms that academics experience in higher education, including women’s submission of publications. This chapter shows how a creative and transdisciplinary intervention, #FEAS FAKE JOURNAL, made space for feminist academics whose scholarship was affected by the pandemic to take part in a project that privileged “unfinished business”. A creative methodology was used that moved beyond the traditional research narrative that relies on mastery and certainty. Seventeen feminist academics participated in the project by submitting an abstract to a fake journal about an unfinished work. Several creative components were used to solicit and support personal, political, and creative accounts to the pandemic. These accounts show how feminist academics were affected by lockdowns, how they managed, and in some cases how they connected with each other. Findings show how transdisciplinary feminist creative activism made space for participants to reflect on the effects of the pandemic and to consider what is worth finishing. This paper shares a rare glimpse into the behind the scenes of knowledge making and doing as unfinished business. It shows how transdisciplinary feminist art activism can be enacted with care and solidarity with others.
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- Saper, Joel, et al.
(författare)
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Rofecoxib in the acute treatment of migraine: a randomized controlled clinical trial
- 2006
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Ingår i: Headache. ; 46:2, s. 264-75
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To investigate the efficacy, tolerability, and safety of rofecoxib and ibuprofen for acute migraine treatment. BACKGROUND: Rofecoxib was effective and well tolerated in a previous study of treatment of a single migraine attack. We sought to replicate these findings for a single attack and also study the clinical profile of rofecoxib in the acute treatment of multiple migraine attacks. Ibuprofen was included as a reference nonselective NSAID. METHODS: Adult migraineurs (n = 783) treated one migraine attack with either rofecoxib (25 or 50 mg), ibuprofen 400 mg, or placebo in a randomized, double-blind study. Patients could elect to enroll in a 3-month double-blind extension phase. RESULTS: In the single-attack phase, headache relief at 2 hours postdose was reported by 59.4%, 62.2%, and 57.7% of patients who took rofecoxib 25 mg, rofecoxib 50 mg, and ibuprofen 400 mg, respectively, versus 30.5% for placebo (all P < .001 vs placebo). The active drugs were statistically superior to placebo on a variety of additional measures. In the extension phase, the mean percentage of patients' attacks with headache relief at 2 hours postdose was 61.8% for rofecoxib 25 mg, 65.4% for rofecoxib 50 mg, and 59.3% for ibuprofen 400 mg. The mean percentage of patients' attacks with 24-hour sustained headache relief was greater for rofecoxib 50 mg (52.0%) than for rofecoxib 25 mg (47.8%, P < .050) or ibuprofen (39.0%, P < .010). In the single-attack phase, the adverse event rate was higher for rofecoxib 50 mg (37.8%) than placebo (27.8%, P < .050); rates were similar to placebo for rofecoxib 25 mg (32.0%, n.s.) and ibuprofen 400 mg (28.1%, n.s.). In the extension phase, treatment groups had similar adverse event rates. CONCLUSIONS: Rofecoxib 25 and 50 mg and ibuprofen 400 mg were effective and generally well tolerated in the acute treatment of migraine.
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