| 1. |
- Andersson, Rolf G, et al.
(författare)
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Studies of the mechanism of desensitization of anti-IgE-mediated histamine release from human basophils
- 1989
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Ingår i: Agents and actions. - 0065-4299. ; 27:1-2, s. 25-28
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Tidskriftsartikel (refereegranskat)abstract
- Human basophils became hyporesponsive to anti-IgE when exposed to this agent in the absence of Ca2+ for more than 10 min. The desensitization process proceeded in parallel to the releasing-process. The mechanism of desensitization seems to involve a very early step in the release-reaction, since the response to phospholipase A2 and diolein, agents involved in the release-reaction, was not affected by the desensitization.
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| 2. |
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| 3. |
- Örtqvist, M., et al.
(författare)
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Knee muscle strength-A challenge to measure
- 2014
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Ingår i: European Journal of Physiotherapy. - : Informa UK Limited. - 2167-9169 .- 2167-9177. ; 16:1, s. 33-40
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Tidskriftsartikel (refereegranskat)abstract
- The aims were to assess the reliability of knee extensor and flexor muscle strength measurements using the Strength Measuring Chair (SMC) in children and adults, and to assess agreement between the SMC and an isokinetic dynamometer (ID). 20 healthy children (10/10 boys/girls, 5-13 years) and 23 adults (10/13 men/women, 23-60 years) were included. Muscle strength tests were performed in the SMC and in the ID. The intra-subject reliability was shown to be excellent in both instruments (ICC 0.93-0.99) and an excellent test-retest reliability of measurements in the SMC was found (ICC 0.87-0.93). Agreement between instruments was evaluated with ICC, paired t-test and Bland-Altman 95% limits of agreement plots. In both adults' and children's groups, disagreements were found between the two instruments, with more in the children's group. The SMC, which has previously shown to be valid and reliable for measuring plantarflexor muscle strength, reliably measured knee muscle strength in healthy children and adults. However, the large disagreement found between the instruments, especially in the children's group, warrants care in standardizing measuring positions for different body size and warrants caution in comparing one's muscle strength measured using different assessment methods.
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| 4. |
- Bartonek, Asa, et al.
(författare)
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A new carbon fibre spring orthosis for children with plantarflexor weakness
- 2007
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Ingår i: Gait & Posture. - : Elsevier BV. - 0966-6362 .- 1879-2219. ; 25:4, s. 652-656
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Tidskriftsartikel (refereegranskat)abstract
- We tested a new orthosis with a carbon fiber spring constructed to enable energy storing during increasing dorsiflexion in mid-stance, and to use the energy at the end of stance phase to aid push-off. The orthosis was tested on children with plantarflexor weakness due to motor disorders. All subjects were tested with 3D gait analysis with both the new orthosis and with their regularly used orthosis. In this technical note, the results of three individuals are reported. The preliminary findings show increased dorsiflexion, altered knee kinematics and improved kinetic and temporo-spatial parameters. Although the carbon spring orthosis influenced the subjects' gait in different ways, we conclude that the tested subjects with plantarflexion weakness benefit from the carbon fiber spring orthoses during walking. The parents' and children's subjective impressions as acquired from a questionnaire were also positive.
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| 5. |
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| 6. |
- Bartonek, Asa, et al.
(författare)
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Effects of carbon fibre spring orthoses on gait in ambulatory children with motor disorders and plantarflexor weakness
- 2007
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Ingår i: Developmental Medicine & Child Neurology. - : Wiley. - 0012-1622 .- 1469-8749. ; 49:8, s. 615-620
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Tidskriftsartikel (refereegranskat)abstract
- A consecutive series of 17 children (six males, 11 females; mean age 11y 11mo [SD 4y 5mo]; range 3y 11mo-17y 4mo) with plantarflexor weakness was assessed to compare gait differences between a carbon fibre spring orthosis (CFSO) and participants' regular orthoses. Twelve children had myelomeningocele, four children had arthrogryposis, and one child had neuropathy with peripheral muscle pareses. All participants underwent clinical examination and 3D gait analysis. Parents answered a questionnaire to assess subjective perceptions of the orthoses. Results from 3D gait analysis provided evidence that CFSOs enhance gait function in most participants by improving ankle plantarflexion moment (p < 0.001), ankle positive work (p < 0.001), and stride length (p < 0.001). The CFSO did not suit all participants, which emphasizes the importance of analyzing each patient's needs.
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| 7. |
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| 8. |
- Bartonek, A., et al.
(författare)
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Influence of external visual focus on gait in children with bilateral cerebral palsy
- 2016
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Ingår i: Pediatric Physical Therapy. - 0898-5669 .- 1538-005X. ; 28:4, s. 393-399
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: To explore whether focusing a target influenced gait in children with cerebral palsy (CP) and typical development (TD). Methods: Thirty children with bilateral CP (Gross Motor Function Classification System [GMFCS] I-III) and 22 with TD looked at a light at walkway end (Gaze Target) while walking and returned (No Target). Results: During Gaze versus No Target, children with TD reduced temporal-spatial parameters and movements in the sagittal (SPM) and transverse planes. In comparison, during Gaze Target, children in CP1 (GMFCS I) had larger trunk SPM, children in CP2 (GMFCS II) larger neck (SPM), and children in CP3 (GMFCS III) greater head and neck frontal plane movements, and reduced cadence and single support. Conclusions: Focusing a target altered gait in children with CP. Children in CP1 reduced movements similar to children with TD, children in CP2 behaved nearly unchanged, whereas children in CP3 reduced movements and temporalspatial parameters, potentially as a consequence of lack of sensory information from lower limbs.
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| 9. |
- Bartonek, Asa, et al.
(författare)
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Influence of heel lifts during standing in children with motor disorders
- 2011
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Ingår i: Gait & Posture. - : Elsevier BV. - 0966-6362 .- 1879-2219. ; 34:3, s. 426-431
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Tidskriftsartikel (refereegranskat)abstract
- Heel wedges may influence standing posture but how and to what extent are unknown. Thirty-two children with motor disorders - 16 with arthrogryposis multiplex congenita (AMC) and 16 with cerebral palsy (CP) - and 19 control children underwent a three-dimensional motion analysis. Unassisted standing during 20s with shoes only and with heel lifts of 10,20 and 30 mm heights was recorded in a randomized order. The more weight-bearing limb or the right limb was chosen for analysis. In both the AMC and CP groups, significant changes were seen between various heel lifts in ankle, knee and pelvis, and in the control group in the ankle only. Between orthosis and non-orthosis users significant differences were seen between different heel lift conditions in ankle, knee and trunk in the AMC group and in the ankle in the CP group. Pelvis position changed toward less anterior tilt with increasing heel height, but led to increasing knee flexion in most of the children, except for the AMC Non-Ort group. Children with AMC and CP represent different motor disorders, but the heel wedges had a similar influence on pelvis, hip and knee positions in all children with CP and in the AMC orthosis users. A challenge is to apply heel heights adequate to each individual's orthopaedic and neurologic conditions to improve biomechanical alignment with respect to all body segments.
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| 10. |
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