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Sökning: WFRF:(Bayer AL)

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1.
  • Bravo, L, et al. (författare)
  • 2021
  • swepub:Mat__t
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  • Khatri, C, et al. (författare)
  • Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study
  • 2021
  • Ingår i: BMJ open. - : BMJ. - 2044-6055. ; 11:11, s. e050830-
  • Tidskriftsartikel (refereegranskat)abstract
    • Studies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients undergoing surgery for proximal femoral fractures and to examine the factors that influence mortality in a multivariate analysis.SettingProspective, international, multicentre, observational cohort study.ParticipantsPatients undergoing any operation for a proximal femoral fracture from 1 February to 30 April 2020 and with perioperative SARS-CoV-2 infection (either 7 days prior or 30-day postoperative).Primary outcome30-day mortality. Multivariate modelling was performed to identify factors associated with 30-day mortality.ResultsThis study reports included 1063 patients from 174 hospitals in 19 countries. Overall 30-day mortality was 29.4% (313/1063). In an adjusted model, 30-day mortality was associated with male gender (OR 2.29, 95% CI 1.68 to 3.13, p<0.001), age >80 years (OR 1.60, 95% CI 1.1 to 2.31, p=0.013), preoperative diagnosis of dementia (OR 1.57, 95% CI 1.15 to 2.16, p=0.005), kidney disease (OR 1.73, 95% CI 1.18 to 2.55, p=0.005) and congestive heart failure (OR 1.62, 95% CI 1.06 to 2.48, p=0.025). Mortality at 30 days was lower in patients with a preoperative diagnosis of SARS-CoV-2 (OR 0.6, 95% CI 0.6 (0.42 to 0.85), p=0.004). There was no difference in mortality in patients with an increase to delay in surgery (p=0.220) or type of anaesthetic given (p=0.787).ConclusionsPatients undergoing surgery for a proximal femoral fracture with a perioperative infection of SARS-CoV-2 have a high rate of mortality. This study would support the need for providing these patients with individualised medical and anaesthetic care, including medical optimisation before theatre. Careful preoperative counselling is needed for those with a proximal femoral fracture and SARS-CoV-2, especially those in the highest risk groups.Trial registration numberNCT04323644
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  • Tabiri, S, et al. (författare)
  • 2021
  • swepub:Mat__t
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  • Komendantova, Nadejda, et al. (författare)
  • Are Energy Security Concerns Dominating Environmental Concerns? Evidence from Stakeholder Participation Processes on Energy Transition in Jordan
  • 2018
  • Ingår i: Climate. - : MDPI AG. - 2225-1154. ; 6:4
  • Tidskriftsartikel (refereegranskat)abstract
    • To satisfy Jordan’s growing demand for electricity and to diversify its energy mix, the Jordanian government is considering a number of electricity-generation technologies that would allow for locally available resources to be used alongside imported energy. Energy policy in Jordan aims to address both climate change mitigation and energy security by increasing the share of low-carbon technologies and domestically available resources in the Jordanian electricity mix. Existing technological alternatives include the scaling up of renewable energy sources, such as solar and wind; the deployment of nuclear energy; and shale oil exploration. However, the views, perceptions, and opinions regarding these technologies—their benefits, risks, and costs—vary significantly among different social groups both inside and outside the country. Considering the large-scale policy intervention that would be needed to deploy these technologies, a compromise solution must be reached. This paper is based on the results of a four-year research project that included extensive stakeholder processes in Jordan, involving several social groups and the application of various methods of participatory governance research, such as multi-criteria decision-making. The results show the variety of opinions expressed and provide insights into each type of electricity-generation technology and its relevance for each stakeholder group. There is a strong prevalence of economic rationality in the results, given that electricity-system costs are prioritized by almost all stakeholder groups.
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