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- Krawczyk, M., et al.
(author)
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Liver Transplantation for Hepatic Trauma: A Study From the European Liver Transplant Registry
- 2016
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In: Transplantation. - : Ovid Technologies (Wolters Kluwer Health). - 0041-1337. ; 100:11, s. 2372-2381
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Journal article (peer-reviewed)abstract
- Background. Liver transplantation is the most extreme form of surgical management of patients with hepatic trauma, with very limited literature data supporting its use. The aim of this study was to assess the results of liver transplantation for hepatic trauma. Methods. This retrospective analysis based on European Liver Transplant Registry comprised data of 73 recipients of liver transplantation for hepatic trauma performed in 37 centers in the period between 1987 and 2013. Mortality and graft loss rates at 90 days were set as primary and secondary outcome measures, respectively. Results. Mortality and graft loss rates at 90 days were 42.5% and 46.6%, respectively. Regarding general variables, cross-clamping without extracorporeal veno-venous bypass was the only independent risk factor for both mortality (P = 0.031) and graft loss (P = 0.034). Regarding more detailed factors, grade of liver trauma exceeding IV increased the risk ofmortality (P = 0.005) and graft loss (P = 0.018). Moreover, a tendency above the level of significance was observed for the negative impact of injury severity score (ISS) onmortality (P = 0.071). The optimal cutoff for ISS was 33, with sensitivity of 60.0%, specificity of 80.0%, positive predictive value of 75.0%, and negative predictive value of 66.7%. Conclusions. Liver transplantation seems to be justified in selected patients with otherwise fatal severe liver injuries, particularly in whom cross-clamping without extracorporeal bypass can be omitted. The ISS cutoff less than 33 may be useful in the selection process.
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| 5. |
- Heil, J., et al.
(author)
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Preoperative portal vein or portal and hepatic vein embolization: DRAGON collaborative group analysis
- 2021
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In: British Journal of Surgery. - : OXFORD UNIV PRESS. - 0007-1323 .- 1365-2168. ; 108:7, s. 834-842
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Journal article (peer-reviewed)abstract
- Y Background: The extent of liver resection for tumours is limited by the expected functional reserve of the future liver remnant (FRL), so hypertrophy may be induced by portal vein embolization (PVE), taking 6 weeks or longer for growth. This study assessed the hypothesis that simultaneous embolization of portal and hepatic veins (PVE/HVE) accelerates hypertrophy and improves resectability. Methods: All centres of the international DRAGON trials study collaborative were asked to provide data on patients who had PVE/HVE or PVE on 2016-2019 (more than 5 PVE/HVE procedures was a requirement). Liver volumetry was performed using OsiriX MD software. Multivariable analysis was performed for the endpoints of resectability rate, FLR hypertrophy and major complications using receiver operating characteristic (ROC) statistics, regression, and Kaplan-Meier analysis. Results: In total, 39 patients had undergone PVE/HVE and 160 had PVE alone. The PVE/HVE group had better hypertrophy than the PVE group (59 versus 48 per cent respectively; P=0.020) and resectability (90 versus 68 per cent; P=0.007). Major complications (26 versus 34 per cent; P=0.550) and 90-day mortality (3 versus 16 per cent respectively, P = 0.065) were comparable. Multivariable analysis confirmed that these effects were independent of confounders. Conclusion: PVE/HVE achieved better FLR hypertrophy and resectability than PVE in this collaborative experience.
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| 6. |
- Su, R., et al.
(author)
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How the Anatase-to-Rutile Ratio Influences the Photoreactivity of TiO2
- 2011
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In: Journal of Physical Chemistry C. - : American Chemical Society (ACS). - 1932-7447 .- 1932-7455. ; 115:49, s. 24287-24292
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Journal article (peer-reviewed)abstract
- In 1991, Bickley et al. proposed a synergetic effect between anatase and rutile in Degussa P25. Since then, there has been an intensive debate about the correctness of this proposal, the origin of the synergism, and the right polymorph composition. However, a comparison of pure titanium dioxide samples with various anatase-to-rutile ratios, but otherwise identical properties, is missing. In this paper, we report about a series of utterly pure, highly porous titanium dioxide films with identical grain sizes, surface areas, and crystallinity, but varying polymorph compositions. Photocatalytic oxidation of methylene blue was utilized to investigate the influence of the anatase-to-rutile ratio on the photoreactivity. We clearly observe the synergetic effect within a well-defined range of anatase-to-rutile ratios. A film with similar to 60% anatase and similar to 40% rutile exhibits optimal performance at a 50% improved activity compared with pure anatase.
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| 7. |
- Su, R., et al.
(author)
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Rapid Synthesis of Porous, Mixed Phase Titania Films with Tailored Orientation of Rutile for Enhanced Photocatalytic Performance
- 2013
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In: Journal of Physical Chemistry C. - : American Chemical Society (ACS). - 1932-7447 .- 1932-7455. ; 117:51, s. 27039-27046
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Journal article (peer-reviewed)abstract
- We report on a new, one-step electrochemical oxidation method for the rapid synthesis of mixed phase, polycrystalline TiO2 porous films with oriented rutile within a few minutes. The orientation as well as the surface chemical composition of rutile nanocrystallites can readily be tuned by adjusting the additive concentrations of HCl or HF in the electrolyte during synthesis. All TiO2 films show similar large specific surface area, which is ideal for the application of photocatalysis and photoelectrocatalysis. Compared to the random-oriented TiO2 film, films with an increasing portion of exposed rutile (101) facets were found to be characterized by enhanced photocatalytic oxidation and photoelectrochemical performances. We also observed a synergistic promotion effect of the orientation and surface F impurity. Most interesting, our tailor-oriented porous TiO2 films prepared using HF as additive show an impressive photocurrent generation at zero bias, which is similar to 50 times higher compared to that of the random-oriented TiO2 film.
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