| 1. |
- Niemi, MEK, et al.
(författare)
-
- 2021
-
swepub:Mat__t
|
|
| 2. |
- Kanai, M, et al.
(författare)
-
- 2023
-
swepub:Mat__t
|
|
| 3. |
|
|
| 4. |
- Demetris, A J, et al.
(författare)
-
2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology: Introduction of Antibody-Mediated Rejection.
- 2016
-
Ingår i: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. - : Elsevier BV. - 1600-6143. ; 16:10, s. 2816-2835
-
Tidskriftsartikel (refereegranskat)abstract
- The Banff Working Group on Liver Allograft Pathology reviewed and discussed literature evidence regarding antibody-mediated liver allograft rejection at the 11th (Paris, France, June 5-10, 2011), 12th (Comandatuba, Brazil, August 19-23, 2013), and 13th (Vancouver, British Columbia, Canada, October 5-10, 2015) meetings of the Banff Conference on Allograft Pathology. Discussion continued online. The primary goal was to introduce guidelines and consensus criteria for the diagnosis of liver allograft antibody-mediated rejection and provide a comprehensive update of all Banff Schema recommendations. Included are new recommendations for complement component 4d tissue staining and interpretation, staging liver allograft fibrosis, and findings related to immunosuppression minimization. In an effort to create a single reference document, previous unchanged criteria are also included.
|
|
| 5. |
|
|
| 6. |
|
|
| 7. |
- Evangelou, Evangelos, et al.
(författare)
-
A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip
- 2014
-
Ingår i: Annals of the Rheumatic Diseases. - : BMJ. - 1468-2060 .- 0003-4967. ; 73:12, s. 2130-2136
-
Tidskriftsartikel (refereegranskat)abstract
- Objectives Osteoarthritis (OA) is the most common form of arthritis with a clear genetic component. To identify novel loci associated with hip OA we performed a meta-analysis of genome-wide association studies (GWAS) on European subjects. Methods We performed a two-stage meta-analysis on more than 78 000 participants. In stage 1, we synthesised data from eight GWAS whereas data from 10 centres were used for 'in silico' or 'de novo' replication. Besides the main analysis, a stratified by sex analysis was performed to detect possible sex-specific signals. Meta-analysis was performed using inverse-variance fixed effects models. A random effects approach was also used. Results We accumulated 11 277 cases of radiographic and symptomatic hip OA. We prioritised eight single nucleotide polymorphism (SNPs) for follow-up in the discovery stage (4349 OA cases); five from the combined analysis, two male specific and one female specific. One locus, at 20q13, represented by rs6094710 (minor allele frequency (MAF) 4%) near the NCOA3 (nuclear receptor coactivator 3) gene, reached genome-wide significance level with p=7.9x10(-9) and OR=1.28 (95% CI 1.18 to 1.39) in the combined analysis of discovery (p= 5.6x10(-8)) and follow-up studies (p=7.3x10(-4)). We showed that this gene is expressed in articular cartilage and its expression was significantly reduced in OA-affected cartilage. Moreover, two loci remained suggestive associated; rs5009270 at 7q31 (MAF 30%, p=9.9x10(-7), OR=1.10) and rs3757837 at 7p13 (MAF 6%, p=2.2x10(-6), OR=1.27 in male specific analysis). Conclusions Novel genetic loci for hip OA were found in this meta-analysis of GWAS.
|
|
| 8. |
- Bailey, Liam D., et al.
(författare)
-
Bird populations most exposed to climate change are less sensitive to climatic variation
- 2022
-
Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 13:1
-
Tidskriftsartikel (refereegranskat)abstract
- The phenology of many species shows strong sensitivity to climate change; however, with few large scale intra-specific studies it is unclear how such sensitivity varies over a species’ range. We document large intra-specific variation in phenological sensitivity to temperature using laying date information from 67 populations of two co-familial European songbirds, the great tit (Parus major) and blue tit (Cyanistes caeruleus), covering a large part of their breeding range. Populations inhabiting deciduous habitats showed stronger phenological sensitivity than those in evergreen and mixed habitats. However, populations with higher sensitivity tended to have experienced less rapid change in climate over the past decades, such that populations with high phenological sensitivity will not necessarily exhibit the strongest phenological advancement. Our results show that to effectively assess the impact of climate change on phenology across a species’ range it will be necessary to account for intra-specific variation in phenological sensitivity, climate change exposure, and the ecological characteristics of a population.
|
|
| 9. |
- Bellamy, R., et al.
(författare)
-
Incentivising bioenergy with carbon capture and storage (BECCS) responsibly : Comparing stakeholder policy preferences in the United Kingdom and Sweden
- 2021
-
Ingår i: Environmental Science and Policy. - : Elsevier Ltd. - 1462-9011 .- 1873-6416. ; 116, s. 47-55
-
Tidskriftsartikel (refereegranskat)abstract
- Bioenergy with carbon capture and storage (BECCS) plays a central role in scenario pathways that limit global warming in line with the objectives of the Paris Agreement. Yet deliberate policy efforts to incentivise BECCS—whether through amending existing climate policies or introducing entirely new ones—remain rare. In this paper, we contend that BECCS must be incentivised responsibly, through policy-making processes which account for diverse and geographically varying societal values and interests. More specifically, we make the case for responsible incentivisation by undertaking a comparative analysis of stakeholder attitudes to four idealised policy scenarios for BECCS, including representatives of government, business, nongovernmental and academic communities, in the UK and Sweden. The scenarios were: business as usual; international policy reform; national BECCS policy; and national policy for negative emissions technologies. Based on our findings, we recommend that policymakers 1) recognise the need to develop new incentives and make enabling reforms to existing policy instruments; 2) consider the risk of mitigation deterrence in their real world (and not abstracted) contexts; 3) employ multi-instrument approaches to incentivisation that do not overly rely on carbon pricing or 4) force a choice between technology specific or technology neutral policies; and 5) attend to the diversity of stakeholder and wider public perspectives that will ultimately determine the success—or failure—of their policy designs.
|
|
| 10. |
|
|
