| 1. |
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- 2019
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Tidskriftsartikel (refereegranskat)
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| 2. |
- Allalou, Amin, 1981-
(författare)
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Methods for 2D and 3D Quantitative Microscopy of Biological Samples
- 2011
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- New microscopy techniques are continuously developed, resulting in more rapid acquisition of large amounts of data. Manual analysis of such data is extremely time-consuming and many features are difficult to quantify without the aid of a computer. But with automated image analysis biologists can extract quantitative measurements and increases throughput significantly, which becomes particularly important in high-throughput screening (HTS). This thesis addresses automation of traditional analysis of cell data as well as automation of both image capture and analysis in zebrafish high-throughput screening. It is common in microscopy images to stain the nuclei in the cells, and to label the DNA and proteins in different ways. Padlock-probing and proximity ligation are highly specific detection methods that produce point-like signals within the cells. Accurate signal detection and segmentation is often a key step in analysis of these types of images. Cells in a sample will always show some degree of variation in DNA and protein expression and to quantify these variations each cell has to be analyzed individually. This thesis presents development and evaluation of single cell analysis on a range of different types of image data. In addition, we present a novel method for signal detection in three dimensions. HTS systems often use a combination of microscopy and image analysis to analyze cell-based samples. However, many diseases and biological pathways can be better studied in whole animals, particularly those that involve organ systems and multi-cellular interactions. The zebrafish is a widely-used vertebrate model of human organ function and development. Our collaborators have developed a high-throughput platform for cellular-resolution in vivo chemical and genetic screens on zebrafish larvae. This thesis presents improvements to the system, including accurate positioning of the fish which incorporates methods for detecting regions of interest, making the system fully automatic. Furthermore, the thesis describes a novel high-throughput tomography system for screening live zebrafish in both fluorescence and bright field microscopy. This 3D imaging approach combined with automatic quantification of morphological changes enables previously intractable high-throughput screening of vertebrate model organisms.
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| 3. |
- Arvidson, Magnus, et al.
(författare)
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Brandskydd på Bo01
- 2001
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Ingår i: Bygg och Teknik. - 0281-658X .- 2002-8350. ; 93:6, s. 12-16
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 4. |
- Bengtsson, Andreas, et al.
(författare)
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Carbon Fibers from Lignin-Cellulose Precursors : Effect of Carbonization Conditions
- 2020
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Ingår i: ACS Sustainable Chemistry and Engineering. - : American Chemical Society. - 2168-0485. ; 8:17, s. 6826-6833
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Tidskriftsartikel (refereegranskat)abstract
- Carbon fibers (CFs) are gaining increasing importance in lightweight composites, but their high price and reliance on fossil-based raw materials stress the need for renewable and cost-efficient alternatives. Kraft lignin and cellulose are renewable macromolecules available in high quantities, making them interesting candidates for CF production. Dry-jet wet spun precursor fibers (PFs) from a 70/30 w/w blend of softwood kraft lignin (SKL) and fully bleached softwood kraft pulp (KP) were converted into CFs under fixation. The focus was to investigate the effect of carbonization temperature and time on the CF structure and properties. Reducing the carbonization time from 708 to 24 min had no significant impact on the tensile properties. Increasing the carbonization temperature from 600 to 800 °C resulted in a large increase in the carbon content and tensile properties, suggesting that this is a critical region during carbonization of SKL:KP PFs. The highest Young's modulus (77 GPa) was obtained after carbonization at 1600 °C, explained by the gradual transition from amorphous to nanocrystalline graphite observed by Raman spectroscopy. On the other hand, the highest tensile strength (1050 MPa) was achieved at 1000 °C, a decrease being observed thereafter, which may be explained by an increase in radial heterogeneity.
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| 5. |
- Bengtsson, Dennis, 1995-, et al.
(författare)
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The effects of interpersonal development programmes with sport coaches and parents on youth athlete outcomes : a systematic review and meta-analysis
- 2024
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Ingår i: Psychology of Sport And Exercise. - Amsterdam : Elsevier. - 1469-0292 .- 1878-5476. ; 70
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Forskningsöversikt (refereegranskat)abstract
- Interpersonal coach-and parent development programmes (CDP and PDP, respectively), have the goal to foster positive youth sport experiences through high-quality relations between coaches, parents, and youth athletes. In this paper we systematically reviewed the extant literature and estimate the overall magnitude of such programmes and how they can inform future interventions. Specifically, we aimed to: (a) conduct a systematic review on the literature of interpersonal CDPs and PDPs within the youth sport context; (b) examine the effects of such interventions on youth athlete outcomes via a meta-analysis. English written peer-reviewed publications and grey literature was identified through electronic search in databases and manual searches of reference lists. By utilising a priori criteria for inclusion and exclusion, 33 studies describing interpersonal CDPs, and PDPs were identified in the systematic review. Studies that presented required data for estimation of Hedge's g effect sizes were included in the meta-analysis (k = 27). By and large, the included studies used a quasi-experimental design (58%), sampled from team sports (79%), and reported several delivery methods (e.g., workshops, audio feedback, observations, peer group discussions) and outcome measures (e.g., anxiety, autonomous motivation, self-confidence). Some interventions were based on the same delivery protocols (e.g., Coach Effectiveness Training, Mastery Approach to Coaching) or theoretical frameworks (e.g., Achievement Goal Theory, Self-Determination Theory). The meta-analysis showed statistically significant small, and medium, effect sizes on a subsample of youth athlete outcomes (e.g., task-related climate, fun and enjoyment, anxiety), indicating that coach interpersonal skills can contribute to positive youth sport experiences. Theory-based interpersonal CDPs and PDPs are recommended to expand the knowledge in this field of research.
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| 6. |
- Bengtsson, Dennis, 1995-, et al.
(författare)
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The effects of interpersonal development programmes with sport coaches and parents on youth athlete outcomes : A systematic review and meta-analysis
- 2024
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Ingår i: Psychology of Sport And Exercise. - Amsterdam : Elsevier. - 1469-0292 .- 1878-5476. ; 70
-
Forskningsöversikt (refereegranskat)abstract
- Interpersonal coach-and parent development programmes (CDP and PDP, respectively), have the goal to foster positive youth sport experiences through high-quality relations between coaches, parents, and youth athletes. In this paper we systematically reviewed the extant literature and estimate the overall magnitude of such programmes and how they can inform future interventions. Specifically, we aimed to: (a) conduct a systematic review on the literature of interpersonal CDPs and PDPs within the youth sport context; (b) examine the effects of such interventions on youth athlete outcomes via a meta-analysis. English written peer-reviewed publications and grey literature was identified through electronic search in databases and manual searches of reference lists. By utilising a priori criteria for inclusion and exclusion, 33 studies describing interpersonal CDPs, and PDPs were identified in the systematic review. Studies that presented required data for estimation of Hedge's g effect sizes were included in the meta-analysis (k = 27). By and large, the included studies used a quasi-experimental design (58%), sampled from team sports (79%), and reported several delivery methods (e.g., workshops, audio feedback, observations, peer group discussions) and outcome measures (e.g., anxiety, autonomous motivation, self-confidence). Some interventions were based on the same delivery protocols (e.g., Coach Effectiveness Training, Mastery Approach to Coaching) or theoretical frameworks (e.g., Achievement Goal Theory, Self-Determination Theory). The meta-analysis showed statistically significant small, and medium, effect sizes on a subsample of youth athlete outcomes (e.g., task-related climate, fun and enjoyment, anxiety), indicating that coach interpersonal skills can contribute to positive youth sport experiences. Theory-based interpersonal CDPs and PDPs are recommended to expand the knowledge in this field of research. © 2023 The Authors
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| 7. |
- Bengtsson, Jens, 1973-
(författare)
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Essays on valuation of manufacturing flexibility : an option-pricing theory approach
- 2000
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Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Flexibility in manufacturing operations is becoming increasingly more important to industrial firms due to e.g. increasing product demand volatility, internationalisation of markets and competition, and shorter product life cycles. Flexibility is hard to evaluate in the traditional way by discounting expected cash flow, but an accessible approach is to consider flexibility as real options and use option-pricing theory. The general purpose of this thesis is to analyse and increase the understanding of product-mix flexibility by using option pricing. Employing option pricing enables a number of flexibility related issues to be analysed. From a manufacturing point of view aspects such as the impact of capacity levels, degree of flexibility in the manufacturing process, and characteristics of product demand are analysed. From a financial point of view aspects such as the impact of correlation between product demand and the market portfolio, and the impact of mean-reverting processes are analysed. The manufacturing contexts are characterised by set-up costs, capacity constraints, and in the presence of several products.
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| 8. |
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| 9. |
- Bengtsson, Jens
(författare)
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Manufacturing flexibility and real options : A review
- 2001
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Ingår i: International Journal of Production Economics. - 0925-5273 .- 1873-7579. ; 74:1-3, s. 213-224
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Forskningsöversikt (refereegranskat)abstract
- This paper considers manufacturing flexibility and real options from an industrial engineering/production management perspective. Real options papers are related to different types of manufacturing flexibility in order to show which types that are considered and in what way they are considered. Flexibility types not valued with real options and real options without any corresponding manufacturing flexibility type are identified and discussed. © 2001 Elsevier Science B.V. All rights reserved.
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| 10. |
- Bengtsson, Jens
(författare)
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Motionsspår i Skåne och Sörmland : en inventering av anläggningar och strategier
- 2015
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Ingår i: LTV-fakultetens faktablad.
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Annan publikation (populärvet., debatt m.m.)abstract
- I takt med att intresset för motion och inte minst löpning ökar i samhället, ställs allt högre krav på att kommunerna ska tillhandahålla vardagsmiljöer som gynnar ett aktivt uteliv. En möjlighet till ett aktivt uteliv finns i de motionscentraler som många kommuner anlade under 1960 till 1980-talen. Syftet med rapporten är att undersöka hur arvet från dessa anläggningar förvaltas idag samt hur kommunerna arbetar strategiskt med frågor kring motionsspår. Rapporten bygger dels på en dokumentstudie av informationsmaterial och policydokument på kommunernas hemsidor, dels på telefonintervjuer med tjänstemän i samtliga kommuner i Skåne län och Sörmlands län.
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