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Sökning: WFRF:(Bennett Rick)

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1.
  • Geirsson, Halldor, et al. (författare)
  • Volcano deformation at active plate boundaries : Deep magma accumulation at Hekla volcano and plate boundary deformation in south Iceland
  • 2012
  • Ingår i: Journal of Geophysical Research. - 0148-0227 .- 2156-2202. ; 117:B11409
  • Tidskriftsartikel (refereegranskat)abstract
    • Most magmatic systems on Earth are located at actively deforming plate boundaries. In these systems, the magmatic and plate boundary deformation signals are intertwined and must be deconvolved to properly estimate magma flux and source characteristics of the magma plumbing system. We investigate the inter-rifting and inter-seismic deformation signals at the Eastern Volcanic Zone (EVZ) - South Iceland Seismic Zone (SISZ) ridge - transform intersection and estimate the location, depth, and volume rate for magmatic sources at Hekla and Torfajokull volcanoes, which are located at the intersection. We solve simultaneously for the source parameters of the tectonic and volcanic deformation signals using a new ten-year velocity field derived from a dense network of episodic and continuous GPS stations in south Iceland. We find the intersection of the axes of the EVZ and the SISZ is located within the Torfajokull caldera, which itself is subsiding. Deformation at Hekla is statistically best described in terms of a horizontal ellipsoidal magma chamber at 24(2)(+4) km depth aligned with the volcanic system and increasing in volume by 0.017(-0.002)(+0.007) km(3) per year. A spherical magma chamber centered at 24(-2)(+5) km depth with a volume rate of 0.019(-0.002)(+0.011) km(3) per year, or a vertical pipe-shaped magma chamber between 10(-1)(+3) km and 21(-4)(+7) km with a volume rate of 0.008(-0.001)(+0.003) km(3) per year are also plausible models explaining the deformation at Hekla. All three models indicate magma accumulation in the lower crust or near the Moho under Hekla.
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2.
  • Lagou, Vasiliki, et al. (författare)
  • Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
  • 2021
  • Ingår i: Nature Communications. - : Nature Publishing Group. - 2041-1723. ; 12:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Differences between sexes contribute to variation in the levels of fasting glucose and insulin. Epidemiological studies established a higher prevalence of impaired fasting glucose in men and impaired glucose tolerance in women, however, the genetic component underlying this phenomenon is not established. We assess sex-dimorphic (73,089/50,404 women and 67,506/47,806 men) and sex-combined (151,188/105,056 individuals) fasting glucose/fasting insulin genetic effects via genome-wide association study meta-analyses in individuals of European descent without diabetes. Here we report sex dimorphism in allelic effects on fasting insulin at IRS1 and ZNF12 loci, the latter showing higher RNA expression in whole blood in women compared to men. We also observe sex-homogeneous effects on fasting glucose at seven novel loci. Fasting insulin in women shows stronger genetic correlations than in men with waist-to-hip ratio and anorexia nervosa. Furthermore, waist-to-hip ratio is causally related to insulin resistance in women, but not in men. These results position dissection of metabolic and glycemic health sex dimorphism as a steppingstone for understanding differences in genetic effects between women and men in related phenotypes.
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