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- Bergström, Anders, 1965-, et al.
(författare)
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Millesgården : Arkitektur & trädgård
- 2004
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Bok (refereegranskat)abstract
- Millesgården på Lidingö norr om Stockholm är ett av Sveriges mest välkända konstnärshem. Här uppförde skulptören Carl Milles från 1908 en kombinerad ateljé och bostad med anslutande trädgård. Trots att Milles var en mycket produktiv och framgångsrik skulptör, finns det skäl att framhålla Millesgården som hans främsta konstnärliga arbete.Millesgårdens tillkomst skildras här i nära anslutning till den samtida utvecklingen inom arkitektur och trädgårdskonst. Anläggningen fungerade inte bara som hem och ateljé, utan även som utställningsmiljö. Millesgården blev ett monument – en minnesgård – där Carl Milles ambitioner och höga anspråk på konstnärsrollen kom till uttryck.
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- Gustavsson, Catharina, et al.
(författare)
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Predictive factors for disability outcome at 20 weeks and 2 years following a pain self-management group intervention in patients with persistent neck pain in primary health care
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- Study design. An explorative, longitudinal, prospective study, with measurement at baseline, 20 weeks and 2 years. Objective. To explore plausible predictors associated with short-term (20 weeks) and long-term (2 years) treatment success in terms of pain-related disability for patients with persistent tension-type neck pain following a multi-component pain and stress self-management group intervention (PASS). Summary of Background Data. In previously reported short-term and long-term follow-up, PASS had better effect on pain control, pain-related self-efficacy, disability and catastrophizing than a control treatment; individually administered physical therapy (IAPT). Identification of patients who are likely to benefit from particular interventions is required. Methods. Data collected from 77 participants assigned to PASS in a randomized controlled trial were explored in order to identify plausible predictors of favorable outcome regarding pain-related disability as measured by the Neck Disability Index (NDI), by use of Pearson correlation analysis, factor analysis (FA) and partial least squares (PLS) and ordinary least squares (OLS) regression analyses. Data from self-assessment questionnaires completed by the participants before intervention, post-treatment (20 weeks) and at 2 years after the intervention, were used. The questionnaire comprised: the Self-Efficacy Scale (SES), the NDI, the Coping Strategies Questionnaire(CSQ), the Hospital Anxiety and Depression Scale (HADS) and questions regarding neck pain and analgesics. Results. Multivariate PLS regression analysis showed that baseline scores in NDI, SES and pain intensity explained only 31% of the variance in disability (NDI) immediately post-treatment (20-week follow-up). PLS regression analysis showed that post-treatment scores in NDI, SES and pain intensity explained 68% of the variance in disability (NDI) at 2 years. Univariate OLS linear regression analyses indicated that each variable contributed significantly to the latter PLS regression model (NDI p<0.001, SES p<0.001, pain intensity p<0.001). Conclusions. Treatment gains, as measured by immediate post-treatment scores at 20-week follow-up, in disability, self-efficacy and pain intensity were associated with long-term outcome in pain-related disability two years post-treatment, in patients with persistent neck pain participating in a self-management group intervention in PHC. Pre-treatment characteristics explained only a small proportion of variance in disability post-treatment. Thus, the intervention appears to be feasible for the majority of persons seeking PHC due to persistent tension-type neck pain.
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- Lidar, Malena, 1973-, et al.
(författare)
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Rädda antibiotikan med kunskap och handling. : Lektionsmaterial för gymnasiet.
- 2022
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Annan publikation (populärvet., debatt m.m.)abstract
- Antibiotikaresistens är ett folkhälsoproblem och en ökad resistensutveckling kan få stora konsekvenser för både individen och samhället, på lokal och global nivå. För att möta den komplexa problematik som vår användning av antibiotika medför behöver elever inte bara lära sig faktakunskaper, de behöver också utveckla handlingskompetens som innefattar bland annat att människor upplever att de har möjligheter att agera utifrån kunskaper, kritiskt tänkande och värderingar. I ett forskningsprojekt har didaktikforskare vid Uppsala universitet tillsammans med biologilärare på högstadiet och gymnasiet tagit fram ett undervisningsmaterial om antibiotikaresistens.
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| 7. |
- Olsson, Catharina, 1968, et al.
(författare)
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Glutamate affect intestinal motility in zebrafish larvae
- 2009
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Ingår i: Neurogastroenterology and motility;2nd International Symposium on “Development of the enteric nervous system. Cells, signals and genes”, Feb 2009, London.
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Konferensbidrag (refereegranskat)
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| 8. |
- Pelaseyed, Thaher, 1979, et al.
(författare)
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The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system
- 2014
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Ingår i: Immunological Reviews. - : Wiley. - 0105-2896 .- 1600-065X. ; 260:1, s. 8-20
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Forskningsöversikt (refereegranskat)abstract
- The gastrointestinal tract is covered by mucus that has different properties in the stomach, small intestine, and colon. The large highly glycosylated gel-forming mucins MUC2 and MUC5AC are the major components of the mucus in the intestine and stomach, respectively. In the small intestine, mucus limits the number of bacteria that can reach the epithelium and the Peyer's patches. In the large intestine, the inner mucus layer separates the commensal bacteria from the host epithelium. The outer colonic mucus layer is the natural habitat for the commensal bacteria. The intestinal goblet cells secrete not only the MUC2 mucin but also a number of typical mucus components: CLCA1, FCGBP, AGR2, ZG16, and TFF3. The goblet cells have recently been shown to have a novel gate-keeping role for the presentation of oral antigens to the immune system. Goblet cells deliver small intestinal luminal material to the lamina propria dendritic cells of the tolerogenic CD103+ type. In addition to the gel-forming mucins, the transmembrane mucins MUC3, MUC12, and MUC17 form the enterocyte glycocalyx that can reach about a micrometer out from the brush border. The MUC17 mucin can shuttle from a surface to an intracellular vesicle localization, suggesting that enterocytes might control and report epithelial microbial challenge. There is communication not only from the epithelial cells to the immune system but also in the opposite direction. One example of this is IL10 that can affect and improve the properties of the inner colonic mucus layer. The mucus and epithelial cells of the gastrointestinal tract are the primary gate keepers and controllers of bacterial interactions with the host immune system, but our understanding of this relationship is still in its infancy.
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- Persson, Jessica, et al.
(författare)
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Oral Care Cards as a Support in Daily Oral Care of Frail Older Adults: Experiences and Perceptions of Professionals in Nursing and Dental Care-A Qualitative Study
- 2022
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Ingår i: International Journal of Environmental Research and Public Health. - : MDPI AG. - 1660-4601 .- 1661-7827. ; 19:15
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Tidskriftsartikel (refereegranskat)abstract
- Frail older adults often have poor oral health. In Sweden, oral care cards are designed to be used as an interprofessional tool for documenting the oral health status of older adults with extensive care needs and to describe oral care recommendations. The aim of this study was to explore nursing and dental professionals' experiences and perceptions of oral care cards. Nursing and dental care staff were interviewed in groups or individually. The recorded data were transcribed verbatim and analyzed using qualitative content analysis. A theme emerged: Navigating an oral care responsibility that is not anchored in the nursing and dental care context. The theme was elucidated in three categories: "Accessibility and usefulness", "Coordination between nursing and dental care", and "Ethical approach". The participants perceived a lack of surrounding frameworks and collaboration concerning oral care and the use of oral care cards. An oral care card could ideally facilitate interprofessional and person-centered oral care. However, oral health does not seem to have found its place in the nursing care context. Further research is needed to investigate how oral care cards ought to be developed and designed to support oral health care work.
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