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- Dhanani, Jayesh A, et al.
(författare)
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A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models
- 2018
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Ingår i: Intensive Care Medicine Experimental. - : Springer Science and Business Media LLC. - 2197-425X. ; 6:1
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Tidskriftsartikel (refereegranskat)abstract
- Nebulised antibiotics are frequently used for the prevention or treatment of ventilator-associated pneumonia. Many factors may influence pulmonary drug concentrations with inaccurate dosing schedules potentially leading to therapeutic failure and/or the emergence of antibiotic resistance. We describe a research pathway for studying the pharmacokinetics of a nebulised antibiotic during mechanical ventilation using in vitro methods and ovine models, using tobramycin as the study antibiotic.
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- Singh, Rajendra, et al.
(författare)
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Review, Analysis, and Implementation of Path Selection Strategies for 2D NoCs
- 2022
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Ingår i: IEEE Access. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 2169-3536. ; 10, s. 129245-129268
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Tidskriftsartikel (refereegranskat)abstract
- Recent advances in very-large-scale integration (VLSI) technologies have offered the capability of integrating thousands of processing elements onto a single silicon microchip. Multiprocessor systems-on-chips (MPSoCs) are the latest creation of this technology evolution. As an interconnection network, Network-on-Chip (NoC) has emerged as a scalable and promising solution for MPSoCs to achieve high performance. In NoCs, a routing algorithm is a critical part of a router and provides a path for a packet toward its destination. Every routing algorithm should exhibit two characteristics. First, the route selection function should provide enough degree of adaptiveness to avoid network congestion. Second, it should not offer stale information on network congestion status to the neighboring routers. Many researchers have investigated network congestion and proposed techniques to control/avoid congestion. Such congestion avoidance-based algorithms significantly improve NoC performance. However, they may result in hardware overhead for side network implementation to collect congestion status. This paper reviews various output selection strategies used by routing algorithms to route a packet on a less congested network region. It also classifies them based on techniques adopted to handle and propagate congestion information. Additionally, this article provides the implementation and analysis details of state-of-art selection methods.
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