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Sökning: WFRF:(Bienstman P.)

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1.
  • Murib, M. S., et al. (författare)
  • Photonic studies on polymer-coated sapphire-spheres: A model system for biological ligands
  • 2015
  • Ingår i: Sensors and Actuators A-Physical. - : Elsevier. - 0924-4247 .- 1873-3069. ; 222, s. 212-219
  • Tidskriftsartikel (refereegranskat)abstract
    • In this study we show an optical biosensor concept, based on elastic light scattering from sapphire micro-spheres. Transmitted and elastic scattering intensity of the microspheres (radius 500 mu m, refractive index 1.77) on an optical fiber half coupler is analyzed at 1510 nm. The 0.43 nm angular mode spacing of the resonances is comparable to the angular mode spacing value estimated using the optical size of the microsphere. The spectral linewidths of the resonances are in the order of 0.01 am, which corresponds to quality factors of approximately 10(5). A polydopamine layer is used as a functionalizing agent on sapphire microspherical resonators in view of biosensor implementation. The varying layer thickness on the microsphere is determined as a function of the resonance wavelength shift. It is shown that polymer functionalization has a minor effect on the quality factor. This is a promising step toward the development of an optical biosensor. (C) 2014 Elsevier B.V. All rights reserved.
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2.
  • Hill, Daniel, et al. (författare)
  • Microfluidic and Transducer Technologies for Lab on a Chip Applications
  • 2010
  • Ingår i: 2010 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC). - : IEEE conference proceedings. - 9781424441242 ; , s. 305-307
  • Konferensbidrag (refereegranskat)abstract
    • Point-of-care diagnostic devices typically require six distinct qualities: they must deliver at least the same sensitivity and selectivity, and for a cost per assay no greater than that of today's central lab technologies, deliver results in a short period of time (<15 min at GP; <2h in hospital), be portable or at least small in scale, and require no or extremely little sample preparation. State-of-the-art devices deliver information of several markers in the same measurement.
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