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1.	Corbalan, R, et al. (author) Analysis of Outcomes in Ischemic vs Nonischemic Cardiomyopathy in Patients With Atrial Fibrillation: A Report From the GARFIELD-AF Registry 2019 In: JAMA cardiology. - : American Medical Association (AMA). - 2380-6591 .- 2380-6583. ; 4:6, s. 526-548 Journal article (peer-reviewed)
2.	Sköldberg, Filip, et al. (author) Identification of AHNAK as a novel autoantigen in systemic lupus erythematosus. 2002 In: Biochemical and biophysical research communications. - : Elsevier BV. - 0006-291X .- 1090-2104. ; 291:4, s. 951-8 Journal article (peer-reviewed)abstract To identify candidate autoantigens associated with arthritis, a rat chondrocyte cDNA library was immunoscreened with serum from a patient with rheumatoid arthritis. One isolated cDNA encoded part of AHNAK, a 700-kDa phosphoprotein with DNA binding properties, that appears to be involved in several signal transduction pathways. Immunoreactivity against an in vitro translated human AHNAK fragment was detected in 4.6% (5/109) of patients with rheumatoid arthritis, 29.5% (18/61) of patients with systemic lupus erythematosus (SLE), and 1.2% (2/172) of blood donors. Anti-AHNAK antibodies reacted with a recombinant human AHNAK fragment and with native AHNAK from C32 cell lysates. In vitro translated AHNAK fragment could be cleaved by granzyme B and caspase-3. Anti-AHNAK positive SLE patients had a higher frequency of homogeneous antinuclear antibody staining patterns and a lower frequency of recent mucosal ulcerations. This is the first report that AHNAK can be targeted by the immune system in autoimmune disease.
3.	Sköldberg, Filip, et al. (author) Identification of AHNAK as a novel autoantigen in systemic lupus erythematosus 2002 In: Biochemical and Biophysical Research Communications. - 0006-291X. ; 291:4, s. 951-958 Journal article (peer-reviewed)

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Type of publication: journal article (3)

Type of content: peer-reviewed (3)

Author/Editor: Gjertsen, E (1); Chen, X. (1); Endo, M. (1); Ferrer, A. (1); Fournier, D. (1); Hirose, M. (1); show more...; Howard, J. (1); Jackson, P. (1); Kim, H. (1); Kobayashi, T. (1); Lee, H. (1); Li, H. (1); Li, L. (1); Liu, B. (1); Love, J. (1); Mueller, K. (1); Mueller, T. (1); Nakamura, T. (1); Nielsen, J. (1); Nowak, S. (1); Takeda, H. (1); Yamaguchi, H. (1); Yamamoto, K. (1); Zhang, R. (1); Haas, S. (1); Mazur, M. (1); Novakova, J. (1); Patel, N. (1); Davies, E. (1); Saito, T (1); Suzuki, S (1); Nikolaev, K. (1); Mori, T. (1); Kuznetsova, E. (1); Li, J. (1); Lutz, G. (1); Wright, D. (1); Kumar, S (1); Zhang, Y. (1); Clark, M. (1); Sharma, S. (1); Gustavsson, M (1); Kato, Y. (1); Ross, A. (1); Schwarz, T. (1); Wilson, P. (1); Yoshida, T. (1); Berge, T. (1); Dominguez, I. (1); Jacobs, P. (1); show less...

University: Uppsala University (2); University of Gothenburg (1); Karolinska Institutet (1)

Language: English (2); Undefined language (1)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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