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2.
  • Andersson, Jenny, et al. (författare)
  • Decision‐Making in Seeking Emergency Care for Stroke Symptoms
  • 2022
  • Ingår i: Stroke: Vascular and Interventional Neurology. - : Ovid Technologies (Wolters Kluwer Health). - 2694-5746. ; 2:6
  • Tidskriftsartikel (refereegranskat)abstract
    • BackgroundPrevious studies have shown that rapid treatment for stroke, especially ischemic stroke, reduces mortality and disability. The focus has mainly been on reducing time from arrival at hospital to start of treatment. However, the main reason for delay is often time from symptom onset to arrival at hospital. This study therefore aimed to explore decision‐making processes after the onset of stroke symptoms in patients experiencing a first‐time stroke.MethodsWe included 36 patients aged 18 and older, all of whom were hospitalized with a first‐time stroke between October 2018 and April 2020. All patients were interviewed once within 4 weeks of symptom onset and before hospital discharge. Eligible patients were identified retrospectively through a targeted review of medical records. The data were collected and analyzed according to the grounded theory methodology.ResultsIn total, 43 potential patients were identified and asked to participate. Overall, 36 patients were included in the study: 17 women (median age 77.0 years, interquartile range 17.5) and 19 men (median age 65.7 years, interquartile range 17.2). All interviewees felt fear, and this affected their decision to seek emergency care. The decision‐making processes were described by the core category of “Acting on fear.” The reason for feeling frightened determined the actions taken. The reasons were sorted into 3 main categories: (1) “seeking care”–recognized stroke symptoms and acted immediately; (2) “pending and reluctance”–suspected stroke but awaited to seek care; and (3) “seeking an explanation”–confused by symptoms.ConclusionWe found that decision‐making when experiencing stroke symptoms was complex. All patients felt fear, which determined their actions. Some patients knew about stroke symptoms and acted immediately. Others suspected stroke but still chose to wait, whereas others were confused and tried to find answers. These results could contribute to form future awareness campaigns.
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3.
  • Andersson, Jenny, et al. (författare)
  • Patient´s description of onset stroke symptoms : Oral Presentations. ESOC 2023 Abstract Book
  • 2023
  • Ingår i: European Stroke Journal. - : Sage Publications. - 2396-9873 .- 2396-9881. ; 8:2, s. 427-427
  • Tidskriftsartikel (refereegranskat)abstract
    • Background and aims: Stroke symptoms vary and could be hard to recognize. In addition, stroke severity has decreased according to the National Institutes of Health Stroke Scale (NISSH), with less pronounced symptoms expression. Knowledge on the patient’s description of stroke symptoms is therefore needed. The aim was to describe patient’s symptoms at stroke onset.Methods: A qualitative content analysis was used. Data were collected through individual interviews with 27 patients (16 men and 11 women, median age 70.4 years). All patients were hospitalized with a first-time stroke. The interviews were conducted within 4 weeks of symptoms onset and before hospital discharge.Results: All patients had symptoms that affected their daily life. Some patients described having multiple symptoms at the same time, others had symptoms that began insidiously and worsened over time. Symptoms such as overwhelming fatigue or nausea were described as Premonition of becoming ill, feeling unwell or that something was wrong. Motoric bodily changes were multifaceted as slurred speech or dizziness, balance difficulties and losing control of the body or motor dysfunction. But also, that the surroundings were distorted, and solid objects moved around. Symptoms of Dazed and affected senses included confusion and visual impairment or headache.Conclusions: Stroke is a complex disease with several different symptoms’ expressions and could be difficult to recognize, especially when symptoms are less typical or perceived as not serious. Increased awareness of stroke symptoms among caregivers and among members of the community is important and needed.
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4.
  • Andersson, Jenny, et al. (författare)
  • Symptoms at stroke onset as described by patients: a qualitative study
  • 2024
  • Ingår i: BMC Neurology. - : Springer Nature. - 1471-2377. ; 24:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Stroke is a common and severe disease that requires prompt care. Symptom expressions as one-sidedweakness and speech difficulties are common and included in public stroke campaigns. For some patients stroke canpresent with subtle and less common symptoms, difficult to interpret. The symptom severity assessed by the NationalInstitutes of Health Stroke Scale has decreased, and symptoms at onset may have changed. Therefore, we aimed toinvestigate how patients describe their symptoms at the onset of a first-time stroke.Methods:The study used a qualitative descriptive design and conventional content analysis. Data were collectedthrough recorded interviews with 27 patients aged 18 years and older hospitalised with a first-time stroke betweenOctober 2018 and April 2020. Data were analysed on a manifest level.Results: Symptoms at stroke onset were presented in two themes: Altered Reality and Discomfort and Changed BodyFunctions and described in five categories. Various types of symptoms were found. All symptoms were perceivedas sudden, persistent, and never experienced before and this appear as a “red thread” in the result. Regardless ofsymptom expressions, no specific symptom was described as more severe than another.Conclusions: Stroke symptoms were described with a variety of expressions. Many described complex symptomsnot typical of stroke, which can make it difficult to recognise the symptoms as a stroke and delay medical care. Publicstroke campaigns should emphasize the importance of seeking medical care at the slightest suspicion of stroke andcould be designed to help achieve this.
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5.
  • Andréasson, Karin, et al. (författare)
  • Body mass index in adolescence, risk of type 2 diabetes and associated complications: A nationwide cohort study of men
  • 2022
  • Ingår i: EClinicalMedicine. - : Elsevier BV. - 2589-5370. ; 46
  • Tidskriftsartikel (refereegranskat)abstract
    • Background Obesity is a predominant factor in development of type 2 diabetes but to which extent adolescent obesity influences adult diabetes is unclear. We investigated the association between body mass index (BMI) in young men and subsequent type 2 diabetes and how, in diagnosed diabetes, adolescent BMI relates to glycemic control and diabetes complications. Methods Baseline data from the Swedish Conscript Register for men drafted 1968-2005 was combined with data from the National Diabetes and Patient registries. Diabetes risk was estimated through Cox regression and Kaplan-Meier survival estimates. Relationships between BMI, glycemic control and diabetes complications were assessed through multiple linear and logistic regression. Findings Among 1,647,826 men, 63,957 (3.88%) developed type 2 diabetes over a median follow-up of 29.0 years (IQR[21.0-37.0]). The risk of diabetes within 40 years after conscription was nearly 40% in individuals with adolescent BMI >= 35 kg/m(2). Compared to BMI 18.5-<20 kg/m(2) (reference), diabetes risk increased in a linear fashion from HR 1.18(95%CI 1.15-1.21) for BMI 20-<22.5 kg/m(2) to HR 15.93(95%CI 14.88-17.05) for BMI >= 35 kg/m(2), and a difference in age at onset of 11.4 years was seen. Among men who developed diabetes, higher adolescent BMI was associated with higher HbA1c levels and albuminuria rates. Interpretation Rising adolescent BMI was associated with increased risk of type 2 diabetes diagnosed at a younger age, with poorer metabolic control, and a greater prevalence of albuminuria, all suggestive of worse prognosis. Copyright (C) 2022 The Authors. Published by Elsevier Ltd.
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6.
  • Anjar, Johanna, et al. (författare)
  • MIS 3 marine and lacustrine sediments at Kriegers Flak, southwestern Baltic Sea
  • 2010
  • Ingår i: Boreas. - : Wiley. - 1502-3885 .- 0300-9483. ; 39:2, s. 360-366
  • Tidskriftsartikel (refereegranskat)abstract
    • Sediment cores from the Kriegers Flak area in the southwestern Baltic Sea show a distinct lithological succession, starting with a lower diamict that is overlain by a c. 10 m thick clay unit that contains peat, gyttja and other organic remains. On top follows an upper diamict that is inter-layered with sorted sediments and overlain by an upward-coarsening sequence with molluscs. In this paper we focus on the clay unit, which has been subdivided into three subunits: (A) lower clay with benthic foraminifera and with diamict beds in the lower part; (B) thin beds of gyttja and peat, which have been radiocarbon-dated to 31-35 14C kyr BP (c. 36-41 cal. kyr BP); and (C) upper clay unit. Based on the preliminary results we suggest the following depositional model: fine-grained sediments interbedded with diamict in the lower part (subunit A) were deposited in a brackish basin during a retreat of the Scandinavian Ice Sheet, probably during the Middle Weichselian. Around 40 kyr BP the area turned into a wetland with small ponds (subunit B). A transgression, possibly caused by the damming of the Baltic Basin during the Kattegat advance at 29 kyr BP, led to the deposition of massive clay (subunit C). The data presented here provide new information about the paleoenvironmental changes occurring in the Baltic Basin following the Middle Weichselian glaciation.
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7.
  • Anjar, Johanna, et al. (författare)
  • Palaeoenvironments in the southern Baltic Sea Basin during Marine Isotope Stage 3 : a multi-proxy reconstruction
  • 2012
  • Ingår i: Quaternary Science Reviews. - : Elsevier BV. - 0277-3791. ; 34, s. 81-92
  • Tidskriftsartikel (refereegranskat)abstract
    • Sediment cores from Kriegers Flak in the southwestern Baltic Sea provide a unique possibility to study the Middle Weichselian history of the Baltic Basin. Three Weichselian interstadial units have been identified and are attributed to Marine Isotope Stage 3 (MIS 3, 60-25 ka). The oldest unit A is characterized by a deglaciation sequence, gradually turning into brackish-water clay. The low-diversity benthic foraminiferal fauna, stable oxygen isotope values and Mg/Ca ratios indicate low temperature and salinity for unit A. A hiatus separates unit A from the overlying unit B, which was deposited in wetlands and shallow lakes between 42 and 36 cal. ka BP. Macrofossil and pollen analyses indicate deposition of unit B in an area dominated by a tree-less open tundra environment, possibly with some birch and pine in sheltered positions. The uppermost unit C is characterized by clay deposition, including redeposition of material from older sediments (unit B). Optically stimulated luminescence (OSL) ages indicate deposition of unit C between 26 and 28.5 ka. Radiocarbon ages of 39 and 40 cal. ka BP for unit C are considered to be too old. The following depositional model is suggested: (I) Isostatic depression of the region after an advance of the Scandinavian Ice Sheet (SIS), most likely the Ristinge ice advance, previously dated to c. 55-50 ka, enabled an inflow of marine waters into the Baltic Basin during the deposition of unit A. (II) Isostatic rebound caused a regression at Kriegers Flak, and a hiatus between units A and B. (III) Wetlands and smaller lakes formed in the uplifted area between 42 and 36 cal. ka BP (unit B). (IV) Deposition of glaciolacustrine clays at Kriegers Flak demonstrates that a growing SIS dammed Kattegat and the Baltic Basin c. 28.5 to 26 ka. The new evidence from Kriegers Flak provides a solid framework for future MIS 3 palaeoenvironmental reconstructions in the circum-Baltic area.
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8.
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9.
  • Berg, Christina, 1963, et al. (författare)
  • Normal weight adiposity in a Swedish population: how well is cardiovascular risk associated with excess body fat captured by BMI?
  • 2015
  • Ingår i: Obesity Science & Practice. - : Wiley. - 2055-2238. ; 1:1, s. 50-58
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective The aim of this study was to examine how well body mass index (BMI) reflects cardiovascular risk associated with excess adiposity in a Swedish population by examining the association between body fat, BMI and cardiovascular risk factors. Methods A total of 3,010 adults participated. Normal weight adiposity was defined as the combination of BMI<25 kg/m2 and percentage body fat ≥35% for women and ≥25% for men. Associations with blood pressure, blood lipids, apolipoproteins and C-reactive protein were analysed in age-adjusted regression models. Results The majority of the individuals with overweight and obesity were correctly classified to adiposity, while a wide range of body fat was observed among the normal weight subjects. In total, 9% of the participants were categorised as normal weight with adiposity. Compared with the normal weight leanness group, participants with normal weight adiposity had higher levels of serum triglycerides, low-density lipoprotein cholesterol, C-reactive protein, apolipoptotein B and the apolipoprotein B/A-I ratio. In normal weight men, adiposity was also associated with higher blood pressure and lower high-density lipoprotein cholesterol. Conclusions Higher percentage of body fat was associated with less favourable risk factor profile even in subjects who were normal weight. Thus, it might be relevant to screen for metabolic risk factors in the upper end of the normal weight category.
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10.
  • Berg, Johanna, 1983, et al. (författare)
  • Continuing decrease in coronary heart disease mortality in sweden
  • 2014
  • Ingår i: BMC Cardiovascular Disorders. - : Springer Science and Business Media LLC. - 1471-2261. ; 14:9
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Deaths from coronary heart disease (CHD) have been decreasing in most Western countries over the last few decades. In contrast, a flattening of the decrease in mortality has been recently reported among younger age groups in some countries. We aimed to determine whether the decrease in CHD mortality is flattening among Swedish young adults.Methods: We examined trends in CHD mortality in Sweden between 1987 and 2009 among persons aged 35 to 84 years using CHD mortality data from the Swedish National Register on Cause of Death. Annual percent changes in rates were examined using Joinpoint software.Results: Overall, CHD mortality rates decreased by 67.4% in men and 65.1% in women. Among men aged 35-54 years, there was a modest early attenuation from a marked initial decrease. In the oldest women aged 75-84 years, an attenuation in the mortality decrease was observed from 1989 to 1992, followed by a decrease, as in all other age groups.Conclusions: In Sweden, coronary heart disease deaths are still falling. We were unable to confirm a flattening of the decline in young people. Death rates continue to decline in men and women across all age groups, albeit at a slower pace in younger men since 1991. Continued careful monitoring of CHD mortality trends in Sweden is required, particularly among young adults. © 2014 Berg et al.; licensee BioMed Central Ltd.
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