| 1. |
- Ademuyiwa, Adesoji O., et al.
(författare)
-
Determinants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries
- 2016
-
Ingår i: BMJ Global Health. - : BMJ Publishing Group Ltd. - 2059-7908. ; 1:4
-
Tidskriftsartikel (refereegranskat)abstract
- Background: Child health is a key priority on the global health agenda, yet the provision of essential and emergency surgery in children is patchy in resource-poor regions. This study was aimed to determine the mortality risk for emergency abdominal paediatric surgery in low-income countries globally.Methods: Multicentre, international, prospective, cohort study. Self-selected surgical units performing emergency abdominal surgery submitted prespecified data for consecutive children aged <16 years during a 2-week period between July and December 2014. The United Nation's Human Development Index (HDI) was used to stratify countries. The main outcome measure was 30-day postoperative mortality, analysed by multilevel logistic regression.Results: This study included 1409 patients from 253 centres in 43 countries; 282 children were under 2 years of age. Among them, 265 (18.8%) were from low-HDI, 450 (31.9%) from middle-HDI and 694 (49.3%) from high-HDI countries. The most common operations performed were appendectomy, small bowel resection, pyloromyotomy and correction of intussusception. After adjustment for patient and hospital risk factors, child mortality at 30 days was significantly higher in low-HDI (adjusted OR 7.14 (95% CI 2.52 to 20.23), p<0.001) and middle-HDI (4.42 (1.44 to 13.56), p=0.009) countries compared with high-HDI countries, translating to 40 excess deaths per 1000 procedures performed.Conclusions: Adjusted mortality in children following emergency abdominal surgery may be as high as 7 times greater in low-HDI and middle-HDI countries compared with high-HDI countries. Effective provision of emergency essential surgery should be a key priority for global child health agendas.
|
|
| 2. |
- Arapovic-Johansson, Bozana, et al.
(författare)
-
Experience of Stress Assessed by Text Messages and Its Association with Objective Workload-A Longitudinal Study
- 2020
-
Ingår i: International Journal of Environmental Research and Public Health. - : MDPI. - 1661-7827 .- 1660-4601. ; 17:3
-
Tidskriftsartikel (refereegranskat)abstract
- Exploring stress trajectories in detail and over a long time may give valuable information in terms of both understanding and practice. We followed a group of primary health care employees in a randomized controlled trial. The objective was to describe their experience of stress, explore the intra-individual variability and examine the association between the experience of stress and the objective workload. Weekly text messages with a single item stress question were distributed in two time series: 12 weeks at the beginning of the trial and 26 weeks after the 6-month follow up. Aggregated objective data about workload were collected from their administration office and related to stress levels. There was a seasonal variation, with higher stress during the fall than in spring and summer. The analysis comparing high and low stress subgroups showed that the stress trajectory of a high-stress subgroup was different from that of a low-stress subgroup. Individuals with high exhaustion scores had higher odds of belonging to a subgroup of individuals with high intra-individual variability in stress experience. The objective workload was measured in two ways and was strongly associated with the stress experience. We found that the lower the productivity, the higher the feeling of stress.
|
|
| 3. |
- Arapovic-Johansson, Bozana, et al.
(författare)
-
Process Evaluation of a Participative Organizational Intervention as a Stress Preventive Intervention for Employees in Swedish Primary Health Care
- 2020
-
Ingår i: International Journal of Environmental Research and Public Health. - : MDPI. - 1661-7827 .- 1660-4601. ; 17:19
-
Tidskriftsartikel (refereegranskat)abstract
- This study is a process evaluation of a trial examining the effects of an organizational intervention (Productivity Measurement and Enhancement System or ProMES) on employee stress. The aims were to explore the implementation process and fidelity to the intervention guidelines, examine the influence of contextual factors (hindrances and facilitators) and explore participants experience of working with ProMES. We used the UK Medical Research Council (MRC) guidance to guide the process evaluation. The recruitment, reach and dose delivered were satisfactory and participation high. The employees felt ProMES clarified priorities, gave control and increased participation in decision-making. However, difficulty in obtaining statistical productivity data from the central administration office (a central feature of the intervention) hindered full implementation and regular feedback meetings. Staffing shortages interfered with the implementation process, while having seven design teams and one consultant prevented all occupational groups from working simultaneously. A detailed examination of access to necessary organizational data should be undertaken before implementing ProMES. We recommend a better introduction for new employees, more work on design and packaging and giving employees more training in how to use the software program. The study contributes to our understanding of process evaluations in research into organizational stress management interventions.
|
|
| 4. |
- Bjorklund, Robert, et al.
(författare)
-
Continuous monitoring of yoghurt fermentation using a noble metal electrode array
- 2009
-
Ingår i: International Journal of Food Science and Technology. - : Wiley. - 0950-5423 .- 1365-2621. ; 44:3, s. 635-640
-
Tidskriftsartikel (refereegranskat)abstract
- An electrochemical probe containing gold, platinum and rhodium working electrodes was used to monitor yoghurt production in a pilot facility. Three commercial starting cultures at 40, 42 and 44 C transformed milk having 1.5% fat content to mild yoghurt products. The electrochemical changes in the broth during fermentation were recorded as current responses from pulse voltammetry over the electrodes. Principal component analysis of the responses generated two-dimensional score plots describing the qualitative fermentation progressions. Two distinct fermentation pathways were observed leading to similar final products. The pH was recorded during the fermentations and the data was used as reference values for creating a partial least squares model for prediction of pH as an example of a quantitative application for the sensor. The relative mean squared error for validation of the model using four probes interchangeably was about 2%. The probe was constructed of materials approved for use in the food industry and did not require a standard glass reference electrode.
|
|
| 5. |
|
|
| 6. |
- Lohela Karlsson, Malin, et al.
(författare)
-
Do Attitudes towards Work or Work Motivation Affect Productivity Loss among Academic Employees?
- 2022
-
Ingår i: International Journal of Environmental Research and Public Health. - : MDPI. - 1661-7827 .- 1660-4601. ; 19:2
-
Tidskriftsartikel (refereegranskat)abstract
- Work motivation and job attitudes are important for productivity levels among academic employees. In situations where employees perceive problems, for example, health-related and work environment-related problems, the ability to perform at work could be affected, which may result in fewer publications, reduced quality and less research funding. Few studies, however, have paid attention to productivity loss among academic employees in order to understand how, or if, the perceived loss is affected by the reported problems, either alone or in combination with work motivation and job attitudes. To evaluate whether attitudes towards work-measured as job satisfaction, organisational commitment and work motivation-are associated with productivity loss in the workplace, a cross-sectional study was conducted. This type of design is required as performance is highly variable and is affected by changes in health and work status. This study includes employees who reported either health-related problems, work environment problems or a combination of both (n = 1475). Linear regression analyses were used to answer the hypotheses. Higher levels of motivation, job satisfaction and organisational commitment were associated with lower levels of productivity loss among employees who experienced either health-related or work environment problems. High work motivation and high commitment were significantly associated with lower levels of productivity loss among employees who experienced a combination of problems. In summary, productivity loss among academic employees is not only affected by health-related problems or problems in the work environment but also by work motivation, job satisfaction and organisational commitment; i.e., these factors seem to buffer, or moderate, the reduction in performance levels for this group of employees.
|
|
| 7. |
- Lomnytska, Marta, et al.
(författare)
-
Platelet protein biomarker panel for ovarian cancer diagnosis
- 2018
-
Ingår i: Biomarker Research. - : BIOMED CENTRAL LTD. - 2050-7771. ; 6
-
Tidskriftsartikel (refereegranskat)abstract
- Background: Platelets support cancer growth and spread making platelet proteins candidates in the search for biomarkers. Methods: Two-dimensional (2D) gel electrophoresis, Partial Least Squares Discriminant Analysis (PLS-DA), Western blot, DigiWest. Results: PLS-DA of platelet protein expression in 2D gels suggested differences between the International Federation of Gynaecology and Obstetrics (FIGO) stages III-IV of ovarian cancer, compared to benign adnexal lesions with a sensitivity of 96% and a specificity of 88%. A PLS-DA-based model correctly predicted 7 out of 8 cases of FIGO stages I-II of ovarian cancer after verification by western blot. Receiver-operator curve (ROC) analysis indicated a sensitivity of 83% and specificity of 76% at cut-off >0.5 (area under the curve (AUC) = 0.831, p < 0.0001) for detecting these cases. Validation on an independent set of samples by DigiWest with PLS-DA differentiated benign adnexal lesions and ovarian cancer, FIGO stages III-IV, with a sensitivity of 70% and a specificity of 83%. Conclusion: We identified a group of platelet protein biomarker candidates that can quantify the differential expression between ovarian cancer cases as compared to benign adnexal lesions.
|
|
| 8. |
- Winquist, Fredrik, et al.
(författare)
-
An electronic tongue in the dairy industry
- 2005
-
Ingår i: Sensors and actuators. B, Chemical. - : Elsevier BV. - 0925-4005 .- 1873-3077. ; 111, s. 299-304
-
Tidskriftsartikel (refereegranskat)abstract
- The concept of electronic tongues or taste sensors has developed rapidly during recent years due to their large potential. They are based on electrochemical sensors combined with multivariate data analysis. Voltammetric electronic tongues have proven valuable in many applications. Due to their ruggedness and simplicity, they have been found especially suitable for on-line monitoring of industrial processes. A voltammetric electronic tongue, specially designed for use in the dairy industry is described. It consisted of four working electrodes (gold, platinum, rhodium and stainless steel), embedded in PEEK (TM). It was mounted in a housing of stainless steel, which was inserted in the process line for direct on-line measurements. The voltammetric electronic tongue was used to follow different sources of milk coming into the process and to monitor the cleaning process. (c) 2005 Elsevier B.V. All rights reserved.
|
|
