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Sökning: WFRF:(Borgström Bengt)

  • Resultat 1-10 av 19
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1.
  • Alm, Björn (författare)
  • The un/selfish leader : Changing notions in a Tamil Nadu village
  • 2006
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • 'The un/selfish' leader explores notions of selfishness, as they were perceived by people in the village of Ekkaraiyur, Tamil Nadu, India, at a time they associated with thorough changes in their lives.Discussing locally held notions about agrarian change, seen as causing the erosion of earlier village loyalties and leading to the emergence of a new type of leaders, the study focus on the censure of the alleged corruption of these leaders. Expressed in a rich repertoire of stories about the ideals of leadership and about the excellence of the past and foreign societies, the censure was routinely voiced in public debates and in everyday conversations.Set against a background an increasing role of the state for the people in Ekkaraiyur, the censure of leaders implied a critique of the contemporary society they were taken to represent. Moreover, the study argues that the critique was grounded in evaluations of individualism and selfishness in human nature.The study is based on fieldwork carried out in Ekkaraiyur between 1988 and 1990
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  • Duan, Rui-Dong, et al. (författare)
  • Is there a specific lysophospholipase in human pancreatic juice?
  • 1993
  • Ingår i: Biochimica et Biophysica Acta. - : Elsevier BV. - 0006-3002. ; 1167:3, s. 326-330
  • Tidskriftsartikel (refereegranskat)abstract
    • The existence of a specific lysophospholipase in human pancreatic juice was evaluated. The proteins were separated by a series of chromatographic steps including Sephacryl S-200, cholate-Sepharose 4B, Sephadex G-100 and CM-Sephadex G-50. The enzyme activities against 1-palmitoyl lysolecithin (LL) as well as tributyrin (TB) and p-nitrophenyl butyrate (PNPB) were determined in all the fractions of these purification procedures. Enzyme activity against LL was always eluted in parallel with activities against TB and PNPB, and no unique activity against LL could be found. The specific activity against LL was 40-times lower than that against PNPB and 200-times lower than that against TB. It is concluded that there is no unique lysophospholipase in human pancreatic juice and that the hydrolysis of lysolecithin is most likely performed by carboxyl ester lipase.
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10.
  • Hard, Joanna, et al. (författare)
  • Conbase : a software for unsupervised discovery of clonal somatic mutations in single cells through read phasing
  • 2019
  • Ingår i: Genome Biology. - : BMC. - 1465-6906 .- 1474-760X. ; 20
  • Tidskriftsartikel (refereegranskat)abstract
    • Accurate variant calling and genotyping represent major limiting factors for downstream applications of single-cell genomics. Here, we report Conbase for the identification of somatic mutations in single-cell DNA sequencing data. Conbase leverages phased read data from multiple samples in a dataset to achieve increased confidence in somatic variant calls and genotype predictions. Comparing the performance of Conbase to three other methods, we find that Conbase performs best in terms of false discovery rate and specificity and provides superior robustness on simulated data, in vitro expanded fibroblasts and clonal lymphocyte populations isolated directly from a healthy human donor.
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