| 1. |
|
|
| 2. |
|
|
| 3. |
|
|
| 4. |
- Mårild, Staffan, et al.
(författare)
-
Parental perceptions of and concerns about child´s body weight in eight European countries - the IDEFICS study
- 2014
-
Ingår i: Obesity Reviews. - Chichester : Wiley-Blackwell Publishing Inc.. - 1467-7881 .- 1467-789X. ; 15:S2, s. 105-105
-
Tidskriftsartikel (refereegranskat)abstract
- Background: Few studies have studied parental perceptions in different settings of their children's weight in relation to objective measurements.Aim: To evaluate parental perceptions of their child's weight category in relation to anthropometric measurements.Key Methods: This was cross-sectional study of 16 220 children, 2–9 year of age, from eight European countries. Parents completed a questionnaire on their perception of the children's weight and concern for future weight deviations. Objective children's weight categories from the International Obesity Task Force were used.Results: Parental weight perception corresponded overall to children's mean body mass index (BMI) z-scores, but there were exceptions, e.g. 63% of parents to children with overweight marked ‘proper weight’. One-third of the total indicated concern for future underweight, most often in parents of children in the overweight category. The strongest predictor for accurate parental weight perception for children with overweight and obesity was BMI z-score (odds ratio [OR] 7.2, 95% confidence interval [CI] 6.1–8.7). Compared to Southern Europe, ORs for accurate parental weight perception were 4.4 (95% CI 3.3–6.0) in Northern Europe and 3.4 (95% CI 2.7–4.2) in Central Europe.Conclusion: Parents of children categorized as being overweight or obese systematically underestimated weight category. Parents differed regionally in accurate perception of weight.
|
|
| 5. |
- Groß, Rüdiger, et al.
(författare)
-
Macromolecular Viral Entry Inhibitors as Broad-Spectrum First-Line Antivirals with Activity against SARS-CoV-2
- 2022
-
Ingår i: Advanced Science. - : Wiley. - 2198-3844. ; 9:20
-
Tidskriftsartikel (refereegranskat)abstract
- Inhibitors of viral cell entry based on poly(styrene sulfonate) and its core–shell nanoformulations based on gold nanoparticles are investigated against a panel of viruses, including clinical isolates of SARS-CoV-2. Macromolecular inhibitors are shown to exhibit the highly sought-after broad-spectrum antiviral activity, which covers most analyzed enveloped viruses and all of the variants of concern for SARS-CoV-2 tested. The inhibitory activity is quantified in vitro in appropriate cell culture models and for respiratory viral pathogens (respiratory syncytial virus and SARS-CoV-2) in mice. Results of this study comprise a significant step along the translational path of macromolecular inhibitors of virus cell entry, specifically against enveloped respiratory viruses.
|
|
| 6. |
- Hansen, Eline P., et al.
(författare)
-
Exploration of extracellular vesicles from Ascaris suum provides evidence of parasite-host cross talk
- 2019
-
Ingår i: Journal of Extracellular Vesicles. - : Wiley. - 2001-3078. ; 8:1
-
Tidskriftsartikel (refereegranskat)abstract
- The prevalent porcine helminth, Ascaris suum, compromises pig health and reduces farm productivity worldwide. The closely related human parasite, A. lumbricoides, infects more than 800 million people representing a disease burden of 1.31 million disability-adjusted life years. The infections are often chronic in nature, and the parasites have a profound ability to modulate their hosts' immune responses. This study provides the first in-depth characterisation of extracellular vesicles (EVs) from different developmental stages and body parts of A. suum and proposes the role of these vesicles in the host-parasite interplay. The release of EVs from the third- (L3) and fourth-stage (L4) larvae and adults was demonstrated by transmission electron microscopy (TEM), and sequencing of EV-derived RNA identified a number of microRNAs (miRNAs) and transcripts of potential host immune targets, such as IL-13, IL-25 and IL-33, were identified. Furthermore, proteomics of EVs identified several proteins with immunomodulatory properties and other proteins previously shown to be associated with parasite EVs. Taken together, these results suggest that A. suum EVs and their cargo may play a role in host-parasite interactions. This knowledge may pave the way to novel strategies for helminth infection control and knowledge of their immune modulatory potential.
|
|
| 7. |
- Petersen, M. A., et al.
(författare)
-
Seksuelle grænser i nattelivet
- 2023
-
Ingår i: Alkohol - en del af dansk kultur på godt og på ondt. - Århus : Aarhus Universitetsforlag. - 9788772196039
-
Bokkapitel (refereegranskat)
|
|
| 8. |
- Regber, Susann, 1956-, et al.
(författare)
-
Parental perceptions of and concerns about child's body weight in eight European countries – the IDEFICS study
- 2013
-
Ingår i: Pediatric Obesity. - Chichester : Wiley-Blackwell. - 2047-6302 .- 2047-6310. ; 8:2, s. 118-129
-
Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: To evaluate parental perceptions of and concern about child's body weight and general health in children in a European cohort.DESIGN: Cross-sectional multi-centre study in eight European countries.PARTICIPANTS: 16,220 children, ages 2-9 years.METHODS: Parents completed a questionnaire regarding children's health and weight and concern about overweight and underweight. Objective children's weight categories from the International Obesity Task Force were used. Logistic regression models were utilized to identify predictors of accurate weight perception.RESULTS: Parental weight perception corresponded overall to children's mean body mass index (BMI) z-scores, with important exceptions. About one-third of the total indicated concern about underweight, paradoxically most often parents of children in the overweight or obesity categories. In 63%, parents of children in the overweight category marked 'proper weight'. The strongest predictor for accurate parental weight perception for children with overweight and obesity was BMI z-score (odds ratio [OR] = 7.2, 95% confidence interval [CI] 6.1-8.7). Compared to Southern Europe, ORs for accurate parental weight perception were 4.4 (95% CI 3.3-6.0) in Northern Europe and 3.4 (95% CI 2.7-4.2) in Central Europe.CONCLUSION: Parents of children categorized as being overweight or obese systematically underestimated weight. Parents differed regionally regarding accurate weight perception and concern about overweight and underweight.
|
|
