| 1. |
- Palmer, Nicholette D, et al.
(författare)
-
A genome-wide association search for type 2 diabetes genes in African Americans.
- 2012
-
Ingår i: PloS one. - San Francisco : Public Library of Science (PLoS). - 1932-6203. ; 7:1, s. e29202-
-
Tidskriftsartikel (refereegranskat)abstract
- African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have examined T2DM using genome-wide association approaches in this ethnicity. The aim of this study was to identify genes associated with T2DM in the African American population. We performed a Genome Wide Association Study (GWAS) using the Affymetrix 6.0 array in 965 African-American cases with T2DM and end-stage renal disease (T2DM-ESRD) and 1029 population-based controls. The most significant SNPs (n = 550 independent loci) were genotyped in a replication cohort and 122 SNPs (n = 98 independent loci) were further tested through genotyping three additional validation cohorts followed by meta-analysis in all five cohorts totaling 3,132 cases and 3,317 controls. Twelve SNPs had evidence of association in the GWAS (P<0.0071), were directionally consistent in the Replication cohort and were associated with T2DM in subjects without nephropathy (P<0.05). Meta-analysis in all cases and controls revealed a single SNP reaching genome-wide significance (P<2.5×10(-8)). SNP rs7560163 (P = 7.0×10(-9), OR (95% CI) = 0.75 (0.67-0.84)) is located intergenically between RND3 and RBM43. Four additional loci (rs7542900, rs4659485, rs2722769 and rs7107217) were associated with T2DM (P<0.05) and reached more nominal levels of significance (P<2.5×10(-5)) in the overall analysis and may represent novel loci that contribute to T2DM. We have identified novel T2DM-susceptibility variants in the African-American population. Notably, T2DM risk was associated with the major allele and implies an interesting genetic architecture in this population. These results suggest that multiple loci underlie T2DM susceptibility in the African-American population and that these loci are distinct from those identified in other ethnic populations.
|
|
| 2. |
|
|
| 3. |
- Bjursell, Cecilia, 1970-, et al.
(författare)
-
Intergenerational learning in a changing world : Knitting generations together
- 2023
-
Ingår i: Ricerche di Pedagogia e Didattica. - : University of Bologna. - 1970-2221. ; 18:2, s. 51-65
-
Tidskriftsartikel (refereegranskat)abstract
- In intergenerational projects, learning a craft is an activity that may be of interest to people of different ages. This paper focuses on knitting as a craft. In most Western societies, knitting is often considered a craft for women, but on Taquile Island, Peru, it is the men who knit. This paper discusses knitting from an intergenerational perspective whilst focusing on gender and culture. To this aim, we introduce an intrinsic case study to examine the role of gender and culture in intergenerational learning. The data used in this study was collected during a visit to Taquile Island. In summary, the study’s findings reveal that (i) on Taquile, members of the community invest in maintaining cultural traditions in opposition to being swept along by (con)temporary social changes; (ii) knitting on Taquile is approached as a practical technique in contrast to Western culture where knitting is connected to the concept of ‘well-being’; and (iii) whilst gender structures may set frames for performance, the Taquile case demonstrates that what is typically considered ‘male’ or ‘female’ may vary.
|
|
| 4. |
- Boström, Ann-Kristin
(författare)
-
Adult learning in a European context
- 2012
-
Ingår i: Journal of Contemporary Educational Studies. - 0038-0474. ; :5, s. 154-163
-
Tidskriftsartikel (refereegranskat)abstract
- The European Commission predicted that the ratio of people aged 65 and more as a percentage of the population aged 15-64 is expected to increase from 25% in 2007 to 54% in 2060. This change in demographics will have an impact on adult education and training because adult education will to a great extent be expected to include older people in the future. How will adult learning and training adapt to this new trend? Will the learning and training for older people be institutionalized, or will it be positioned in the informal sector? Or could this be organized from the top or by political decisions considering the importance of the motivation, psychological, and health status of the participants as well as the understanding of the degree of flexibility and understanding from the trainers and educators? The intergenerational gap that will exist between older participants and younger professionals might be overcome but should be taken into account.
|
|
| 5. |
- Boström, Ann-Kristin, 1947-
(författare)
-
Att återerövra kunskap som försvunnit [bloggpost]
- 2022
-
Annan publikation (populärvet., debatt m.m.)abstract
- Ingress: En hel del av de kunskaper och erfarenheter som förr var allas gemensamma egendom föll i glömska när industrialiseringen tog över hantverksnäringar.
|
|
| 6. |
|
|
| 7. |
- Boström, Ann-Kristin, 1947-, et al.
(författare)
-
Changing Notions of Lifelong Education and Lifelong Learning
- 2002
-
Ingår i: International Review of Education. - The Netherlands : Kluver Academic Publishers. - 0020-8566 .- 1573-0638. ; 48:1/2, s. 93-110
-
Tidskriftsartikel (refereegranskat)abstract
- Drawing on material from IRE as well as other sources, this article describes how the the notion of lifelong education came into prominicence in the educational world in the late 1960s, how it related to the concepts of formal, non-formal and informal education, and how it contrasted with the idea of recurrent education, as promoted by the OECD. The author goes on to discuss the emergence of the broader and more holistic concept of lifelong learning and the various ways in which it is understood. The article shows how IRE and its host institute have played an important part in the debate on these issues.
|
|
| 8. |
|
|
| 9. |
|
|
| 10. |
|
|
