| 1. |
- Ashmore, J, et al.
(författare)
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The remarkable cochlear amplifier
- 2010
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Ingår i: Hearing research. - : Elsevier BV. - 1878-5891 .- 0378-5955. ; 266:1-2, s. 1-17
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Tidskriftsartikel (refereegranskat)
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| 2. |
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| 3. |
- Blair, SN, et al.
(författare)
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Body weight change, all-cause mortality, and cause-specific mortality in the Multiple Risk Factor Intervention Trial
- 1993
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Ingår i: Annals of Internal Medicine. ; 119, s. 749-757
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Tidskriftsartikel (refereegranskat)abstract
- Cooper Institute for Aerobics Research, Dallas, Texas. OBJECTIVE: To evaluate the relation between weight variability and death in high-risk, middle-aged men participating in the Multiple Risk Factor Intervention Trial (MRFIT). DESIGN: Cohort study with 3.8 years of follow-up. SETTING: Multicenter, collaborative, primary prevention trial conducted at 22 clinical centers in the United States. PARTICIPANTS: Men (n = 10,529) who were 35 to 57 years old at baseline and who were in the upper 10% to 15% of risk for coronary heart disease because of smoking, high blood pressure, and elevated cholesterol level. Participants were seen at least annually for 6 to 7 years for medical evaluations in study clinical centers. MEASUREMENTS: Death from cardiovascular disease (228 deaths) and from all causes (380 deaths). RESULTS: The primary measure of weight variability was the intrapersonal standard deviation of weight (ISD), which was calculated from measured weights obtained at clinic visits during a 6- to 7-year period. All-cause death rates per 1000 person-years of follow-up across ISD quartiles were 8.28, 8.25, 10.57, and 11.07 from the first to fourth quartiles, respectively. After adjusting for baseline risk factors associated with weight change, the relative risk for all-cause mortality in the fourth compared with the first quartile was 1.64 (95% CI, 1.21 to 2.23). Cardiovascular death and ISD showed a similar pattern. The association between weight change and death was not observed in the heaviest men. CONCLUSION: Greater weight variability was associated with a greater risk for cardiovascular disease and all-cause mortality in some types of high-risk men. PMID: 8363210 [PubMed - indexed for MEDLINE]
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| 4. |
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| 5. |
- Lissner, Lauren, 1956, et al.
(författare)
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Variability of body weight and health outcomes in the Framingham population
- 1991
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Ingår i: New England Journal of Medicine. ; 324, s. 1839-1844
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Tidskriftsartikel (refereegranskat)abstract
- Department of Primary Health Care, Redbergsägen #6, Göteborg, Sweden. BACKGROUND. Fluctuation in body weight is a common phenomenon, due in part to the high prevalence of dieting. In this study we examined the associations between variability in body weight and health end points in subjects participating in the Framingham Heart Study, which involves follow-up examinations every two years after entry. METHODS. The degree of variability of body weight was expressed as the coefficient of variation of each subject's measured body-mass-index values at the first eight biennial examinations during the study and on their recalled weight at 25 years of age. Using the 32-year follow-up data, we analyzed total mortality, mortality from coronary heart disease, and morbidity due to coronary heart disease and cancer in relation to intraindividual variation in body weight, including only end points that occurred after the 10th biennial examination. We used age-adjusted proportional-hazards regression for the data analysis. RESULTS. Subjects with highly variable body weights had increased total mortality (P = 0.005 for men, P = 0.01 for women), mortality from coronary heart disease (P = 0.009 for men, P = 0.009 for women), and morbidity due to coronary heart disease (P = 0.0009 for men, P = 0.006 for women). Using a multivariate analysis that also controlled for obesity, trends in weight over time, and five indicators of cardiovascular risk, we found that the positive associations between fluctuations in body weight and end points related to mortality and coronary heart disease could not be attributed to these potential confounding factors. The relative risks of these end points in subjects whose weight varied substantially, as compared with those whose weight was relatively stable, ranged from 1.27 to 1.93. CONCLUSIONS. Fluctuations in body weight may have negative health consequences, independent of obesity and the trend of body weight over time. PMID: 2041550 [PubMed - indexed for MEDLINE]
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| 6. |
- Lissner, Lauren, 1956, et al.
(författare)
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Weight reduction diets and health promotion
- 1992
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Ingår i: American Journal of Preventive Medicine. ; 8, s. 154-158
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Tidskriftsartikel (refereegranskat)abstract
- Department of Primary Health Care, Gothenburg, Sweden. Obesity is an important health problem. Despite record rates of dieting and the availability of numerous programs, the problem is not abating. This article discusses the popularity of fad diets, the safety and effectiveness of commonly used approaches to weight loss, and the health effects of weight change. We propose an approach in which the search for a best treatment is secondary to the development of criteria to match patients to different treatments. This approach provides an opportunity for the health professional to take advantage of the multiple weight reduction resources in the community. PMID: 1633002 [PubMed - indexed for MEDLINE]
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