| 1. |
- Algaba, Juan-Carlos, et al.
(författare)
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Broadband Multi-wavelength Properties of M87 during the 2017 Event Horizon Telescope Campaign
- 2021
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Ingår i: Astrophysical Journal Letters. - : American Astronomical Society. - 2041-8213 .- 2041-8205. ; 911:1
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Forskningsöversikt (refereegranskat)abstract
- In 2017, the Event Horizon Telescope (EHT) Collaboration succeeded in capturing the first direct image of the center of the M87 galaxy. The asymmetric ring morphology and size are consistent with theoretical expectations for a weakly accreting supermassive black hole of mass ∼6.5 × 109 M o˙. The EHTC also partnered with several international facilities in space and on the ground, to arrange an extensive, quasi-simultaneous multi-wavelength campaign. This Letter presents the results and analysis of this campaign, as well as the multi-wavelength data as a legacy data repository. We captured M87 in a historically low state, and the core flux dominates over HST-1 at high energies, making it possible to combine core flux constraints with the more spatially precise very long baseline interferometry data. We present the most complete simultaneous multi-wavelength spectrum of the active nucleus to date, and discuss the complexity and caveats of combining data from different spatial scales into one broadband spectrum. We apply two heuristic, isotropic leptonic single-zone models to provide insight into the basic source properties, but conclude that a structured jet is necessary to explain M87's spectrum. We can exclude that the simultaneous γ-ray emission is produced via inverse Compton emission in the same region producing the EHT mm-band emission, and further conclude that the γ-rays can only be produced in the inner jets (inward of HST-1) if there are strongly particle-dominated regions. Direct synchrotron emission from accelerated protons and secondaries cannot yet be excluded.
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| 2. |
- Ali, Tara, 1980-, et al.
(författare)
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Liquid extraction of low molecular mass organic acids and hydroxamate siderophores from boreal forest soil
- 2011
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Ingår i: Soil Biology and Biochemistry. - : Elsevier BV. - 0038-0717 .- 1879-3428. ; 43:12, s. 2417-2422
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Tidskriftsartikel (refereegranskat)abstract
- Low molecular mass organic acids (LMMOAs) and hydroxamate siderophores (HS) are molecules secreted by microbes and have previously been found in soil solution and in cultures. Mycorrhizal fungi are suggested to be involved in the nutrient uptake processes of trees and weathering of minerals. In this study soil samples taken from the O and E horizons of a podzol were extracted with 10 mM potassium phosphate buffer at pH 7.2. Variable parameters included addition of methanol to the extraction buffer and the use of ultrasonication or rotary shaking during extraction. LMMOAs and HS content of the soil extracts were determined. Analysis of soil extracts were carried out by liquid chromatography mass spectrometry (LC-MS) and the extraction results compared to results for soil solution samples obtained by centrifugation of the soils sampled. The extraction yields were significantly increased by addition of methanol to the extraction buffer, especially for the O horizon samples. Rotary shaking of the samples for 90 min gave slightly higher yields than ultrasonication for 15 min but the reduction in extraction time makes ultrasonication an attractive option. Of the HSs determined, ferricrocin was found in all samples. Optimal extraction conditions showed citric acid and isocitric acid to be the most abundant organic acids in the O and E horizons, respectively.
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| 3. |
- Alimohammadzadeh, Rana
(författare)
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Eco-friendly and Catalytic Surface Engineering of Cellulose and Nanocellulose
- 2021
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The non-stop use of petroleum-based materials such as plastics can generate significant environmental problems, including pollution of the oceans and increased CO2 levels, and cause diseases like cancer due to the starting monomers. Consequently, increased use of sustainable and non-toxic polymers and monomers is required to address these issues. Cellulose, generously supplied by Mother Nature, is the most abundant biopolymer on Earth. Nanocellulose is a sustainable polymer extracted from the cellulose inwood or produced by bacteria and algae. This biodegradable nanomaterialhas recently been receiving intense research attention, since it has great potential for use in a broad range of industrial and biomedical applications. However, it has limitations such as moisture sensitivity and incompatibility with hydrophobic materials due to its hydrophilic nature. Chemical modification is necessary for it to fulfill the requirements for applications that require high moisture resistance and water repellency. Unfortunately, several of the existing methods involve harsh and toxic conditions or reagents. In this thesis, together with my co-workers, I have employed the toolbox of organocatalysis for accomplishing eco-friendly and innovative surface modification of cellulose and nanocellulose. The organocatalysts we usedmost in our research are the naturally abundant and industrially relevantorganic acids tartaric acid and citric acid.Direct catalytic esterification of cellulose nanocrystal (CNC) with thioglycolicacid was performed either in suspension or on solid surfaces such as films and foams. We found that the reaction was accelerated by tartaric acid but could also be autocatalytic with respect to the thioglycolic acid under certain conditions. The synthesized CNC-SH was further exploited as a heterogeneous reducing agent as well as a handle for further nanocellulose modifications. This was demonstrated by using CNC-SH as a heterogenous reducing agent of Cu(II) to Cu(I), which is essential for allowing the Cu to actas a catalyst for 2,3-dipolar cycloaddition reactions between azides andalkynes. We also showed that the thia-modified CNC could undergo further functionalizing via thiol-ene click chemistry reactions, for example, we attached fluorescent compounds such as TAMRA and quinidine.Herein we provide a fluorine-free method to prepare superhydrophobic CNC film with excellent water-resistance properties by combining self-assemblyand organocatalysis. Self-assembly of CNC via vacuum filtration resulted in xa film with a specific roughness at the microscale. Next, the catalytic silylation with a variety of alkoxysilanes in the presence of natural organic acids such as tartaric acid and citric acid was performed. The successful implementation of our method resulted in a super-hydrophobic CNC film (water contact angleover 150°) with excellent water-resistance. Thus, the combination of the selfassembly of a rough surface with catalytic surface modification resulted in a phenomenon like the “lotus effect” as exhibited by the leaves of the lotus flower. An investigation of the oxygen permeability of the octadecyltrimethoxysilane-modified CNC film revealed that it significantly decreased at high relative humidity compared with unmodified CNC films.In this thesis, the fabrication of hydrophobic and functionalized MTM/CNF nanocomposites using organocatalytic surface modification with a large variety of alkoxysilanes is also performed. The surface modifications are mildand the mechanical strength of the Nacre-mimetic nanocomposites is preserved. Elemental mapping analysis revealed that the silane modification occurred predominantly on the surface.A combination of organocatalyst and biopolyelectrolyte complex was appliedfor surface engineering of chemi-thermomechanical pulp (CTMP) and bleached sulfite pulp (BSP). The reaction was performed using a synergistic combination of an organocatalyst with a polyelectrolyte (PE) complex. Using this method, the strength properties of CTMP and BSP sheets were significantly increased (up to 100% in Z-strength for CTMP). Further investigations of the distribution of the PE complex were then performed using TAMRA and quinidine labeling and confocal laser scanningmicroscopy. This revealed that an even distribution of the cationic starch component of the PE complex had occurred within the CTMP-based paper sheets, which follows its lignin distribution pattern.
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| 4. |
- Boija, Susanne, et al.
(författare)
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Determination of conditional stability constants for some divalent transition metal ion-EDTA complexes by electrospray ionization mass spectrometry
- 2014
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Ingår i: Journal of Mass Spectrometry. - : Wiley. - 1076-5174 .- 1096-9888. ; 49:7, s. 550-556
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Tidskriftsartikel (refereegranskat)abstract
- Conditional stability constants of coordination complexes comprising divalent transition metals, Cu2+, Ni2+, Zn2+, Co2+, and ethylenediaminetetraacetic acid (EDTA) were determined utilizing electrospray ionization mass spectrometry. The deviation of signal response of a reference complex was monitored at addition of a second metal ion. The conditional stability constant for the competing metal was then determined through solution equilibria equations. The method showed to be applicable to a system where Co2+ and Zn2+ competed for EDTA at pH 5. When Cu2+ and Ni2+ competed for EDTA, the equilibrium changed over time. This change was shown to be affected in rate and size by the type of organic solvent added. In this work, 30% of either methanol or acetonitrile was used. It was found that if calibration curves are prepared for both metal complexes in solution and the measurements are repeated with sufficient time space, any change in equilibrium of sample solutions will be discovered. Copyright © 2014 John Wiley & Sons, Ltd. Copyright © 2014 John Wiley & Sons, Ltd.
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| 5. |
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| 6. |
- Bylund, Dan, et al.
(författare)
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Analysis of low molecular mass organic acids in natural waters by ion exclusion chromatography tandem mass spectrometry
- 2007
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Ingår i: Journal of Chromatography A. - : Elsevier BV. - 0021-9673 .- 1873-3778. ; 1176:1-2, s. 89-93
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Tidskriftsartikel (refereegranskat)abstract
- A sensitive and selective method for the analysis of aliphatic low molecular mass organic acids (LMMOAs) in natural waters is presented. The method is based on separation with ion exclusion chromatography and detection with electrospray ionization tandem mass spectrometry (LC-MS/MS). The extra selectivity gained by applying MS/MS allows for a minimum of sample preparation and the use of a sub-optimal mobile phase regarding chromatographic resolution. Instead the mobile phase, comprising aqueous formic acid With methanol as organic modifier, was mainly optimized for maximum sensitivity and long term MS stability. Detection limits for malonic, fumaric, maleic, succinic, citraconic, glutaric, malic, alpha-ketoglutaric, tartaric, shikimic, trans-aconitic, cis-aconitic, isocitric and citric acid were in the range 1-50 nM, while the detection limits for pyruvic, oxalic and lactic acid were around 250 nM for an injection volume of 100 mu L. Due to their metal-chelating properties, these LMMOAs are all considered to affect the bioavailability of metals and to be involved in soil forming processes. It is thus of interest to be able to monitor their presence in natural waters, and the method developed within this work was successfully applied for the analysis of LMMOAs in soil solution and stream water samples.
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| 7. |
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| 8. |
- Bylund, Dan, et al.
(författare)
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Chromatographic alignment by warping and dynamic programming as a pre-processing tool for PARAFAC modelling of liquid chromatography-mass spectrometry data
- 2002
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Ingår i: Journal of Chromatography A. - 0021-9673. ; 961:2, s. 237-244
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Tidskriftsartikel (refereegranskat)abstract
- Solutes analysed with LC–MS are characterised by their retention times and mass spectra, and quantified by the intensities measured. This highly selective information can be extracted by multiway modelling. However, for full use and interpretability it is necessary that the assumptions made for the model are valid. For PARAFAC modelling, the assumption is a trilinear data structure. With LC–MS, several factors, e.g. non-linear detector response and ionisation suppression may introduce deviations from trilinearity. The single largest problem, however, is the retention time shifts not related to the true sample variations. In this paper, a time warping algorithm for alignment of LC–MS data in the chromatographic direction has been examined. Several refinements have been implemented and the features are demonstrated for both simulated and real data. With moderate time shifts present in the data, pre-processing with this algorithm yields approximately trilinear data for which reasonable models can be made.
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| 9. |
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| 10. |
- Bylund, Dan, et al.
(författare)
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Optimisation of chromatographic separations by use of a chromatographic response function, empirical modelling and multivariate analysis
- 1997
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Ingår i: Chromatographia. - 0009-5893. ; 44:1/2, s. 74-80
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Tidskriftsartikel (refereegranskat)abstract
- The chiral separation of the drug substance R,S-oxybutynin chloride on a reversed phase HPLC system has been optimised by use of empirical modelling and multivariate analysis. The separation was characterised by a new chromatographic response function developed to modulate both quality of separation and retention time. The study includes a comparison between three different multivariate techniques (multi-layer feed-forward neural networks, multiple linear regression and partial least squares regression) of their capabilities to model the new chromatographic response function and predict its value for new experiments. It was indicated that the most accurate models were achieved with neural networks, although partial least squares regression could also be used to solve the problem since it gives the major directions for the optimal settings of the variables.
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