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- Morice, A. H., et al.
(författare)
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A worldwide survey of chronic cough: a manifestation of enhanced somatosensory response
- 2014
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Ingår i: European Respiratory Journal. - : European Respiratory Society (ERS). - 0903-1936 .- 1399-3003. ; 44:5, s. 1149-1155
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Tidskriftsartikel (refereegranskat)abstract
- Reports from individual centres suggest a preponderance of females with chronic cough. Females also have heightened cough reflex sensitivity. Here we have reviewed the age and sex of unselected referrals to 11 cough clinics. To investigate the cause of any observed sex dimorphism, functional magnetic resonance imaging of putative cough centres was analysed in normal volunteers. The demographic profile of consecutive patients presenting with chronic cough was evaluated. Cough challenge with capsaicin was undertaken in normal volunteers to construct a concentration-response curve. Subsequent functional magnetic resonance imaging during repeated inhalation of sub-tussive concentrations of capsaicin observed areas of activation within the brain and differences in the sexes identified. Of the 10,032 patients presenting with chronic cough, two-thirds (6591) were female (mean age 55 years). The patient profile was largely uniform across centres. The most common age for presentation was 60-69 years. The maximum tolerable dose of inhaled capsaicin was lower in females; however, a significantly greater activation of the somatosensory cortex was observed. Patients presenting with chronic cough from diverse racial and geographic backgrounds have a strikingly homogeneous demographic profile, suggesting a distinct clinical entity. The preponderance of females may be explained by sex-related differences in the central processing of cough sensation. ©ERS 2014.
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- Aharonian, Felix, et al.
(författare)
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Atmospheric gas dynamics in the Perseus cluster observed with Hitomi
- 2018
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Ingår i: Publications of the Astronomical Society of Japan. - : Oxford University Press (OUP). - 0004-6264 .- 2053-051X. ; 70:2
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Tidskriftsartikel (refereegranskat)abstract
- Extending the earlier measurements reported in Hitomi collaboration (2016, Nature, 535, 117), we examine the atmospheric gas motions within the central 100 kpc of the Perseus cluster using observations obtained with the Hitomi satellite. After correcting for the point spread function of the telescope and using optically thin emission lines, we find that the line-of-sight velocity dispersion of the hot gas is remarkably low and mostly uniform. The velocity dispersion reaches a maxima of approximately 200 km s(-1) toward the central active galactic nucleus (AGN) and toward the AGN inflated northwestern ghost bubble. Elsewhere within the observed region, the velocity dispersion appears constant around 100 km s(-1). We also detect a velocity gradient with a 100 km s(-1) amplitude across the cluster core, consistent with large-scale sloshing of the core gas. If the observed gas motions are isotropic, the kinetic pressure support is less than 10% of the thermal pressure support in the cluster core. The well-resolved, optically thin emission lines have Gaussian shapes, indicating that the turbulent driving scale is likely below 100 kpc, which is consistent with the size of the AGN jet inflated bubbles. We also report the first measurement of the ion temperature in the intracluster medium, which we find to be consistent with the electron temperature. In addition, we present a new measurement of the redshift of the brightest cluster galaxy NGC 1275.
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- Fernando, H. N. J., et al.
(författare)
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Characterization of ultra-violet-induced changes in planar waveguides
- 2003
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Ingår i: Journal of Optics. A, Pure and applied optics. - : IOP Publishing. - 1464-4258 .- 1741-3567. ; 5:4, s. 335-340
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Tidskriftsartikel (refereegranskat)abstract
- A simple, low-cost spectrophotometer system operating in reflection absorption mode is used to characterize changes in refractive index and thickness of thin films under 193 nm irradiation. The results indicate overall dilation of the glass and are confirmed by additional surface topographic measurements. We also show that in addition to the net relaxation from laser annealing of the interface, in germanosilicate samples local compaction takes place. Since the net relaxation is triggered by remote interactions, it is not spatially confined to the laser-irradiated area. However, a local positive index change is observed. These results are in agreement with previous hypotheses put forward to explain planar waveguide negative index changes. They also bring to attention the great care necessary in both conducting and interpreting measurements that do not take into account spatial variations arising from the combination of remote and local triggers of both index and thickness changes.
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| 7. |
- Frank, U, et al.
(författare)
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ESVM Guideline on peripheral arterial disease
- 2019
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Ingår i: VASA. Zeitschrift fur Gefasskrankheiten. - : Hogrefe Publishing Group. - 0301-1526. ; 48:Suppl 102, s. 7-79
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Tidskriftsartikel (refereegranskat)
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| 10. |
- Fernando, Harendra, et al.
(författare)
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Engineering UV-photosensitivity in planar lightwave circuits by plasma enhanced chemical vapour deposition
- 2004
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Ingår i: Journal of Physics D. - : IOP Publishing. - 0022-3727 .- 1361-6463. ; 37:20, s. 2804-2809
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Tidskriftsartikel (refereegranskat)abstract
- Ion bombarding conditions were used to modify glass properties in silica-on-silicon systems during plasma enhanced chemical vapour deposition (PECVD). The induced structural modifications in the SiO2/Si system resulted in different photosensitive responses when irradiated by ArF pulsed laser operating at 193 nm wavelength. Fourier transform infrared spectroscopy was used to study the structural modifications triggered by ion bombarding conditions during film growth. The results were further confirmed by additional characterizations with regard to density (etch rate), refractive index and surface topographic measurements. The demonstrated method could be used not only to engineer UV-photosensitivity but also to control and compensate birefringence in planar lightwave devices.
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