| 1. |
- Edgecock, T. R., et al.
(författare)
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High intensity neutrino oscillation facilities in Europe
- 2013
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Ingår i: Physical Review Special Topics - Accelerators and Beams. - : American Physical Society. - 1098-4402. ; 16:2, s. 021002-
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Tidskriftsartikel (refereegranskat)abstract
- The EUROnu project has studied three possible options for future, high intensity neutrino oscillation facilities in Europe. The first is a Super Beam, in which the neutrinos come from the decay of pions created by bombarding targets with a 4 MW proton beam from the CERN High Power Superconducting Proton Linac. The far detector for this facility is the 500 kt MEMPHYS water Cherenkov, located in the Frejus tunnel. The second facility is the Neutrino Factory, in which the neutrinos come from the decay of mu(+) and mu(-) beams in a storage ring. The far detector in this case is a 100 kt magnetized iron neutrino detector at a baseline of 2000 km. The third option is a Beta Beam, in which the neutrinos come from the decay of beta emitting isotopes, in particular He-6 and Ne-18, also stored in a ring. The far detector is also the MEMPHYS detector in the Frejus tunnel. EUROnu has undertaken conceptual designs of these facilities and studied the performance of the detectors. Based on this, it has determined the physics reach of each facility, in particular for the measurement of CP violation in the lepton sector, and estimated the cost of construction. These have demonstrated that the best facility to build is the Neutrino Factory. However, if a powerful proton driver is constructed for another purpose or if the MEMPHYS detector is built for astroparticle physics, the Super Beam also becomes very attractive.
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| 2. |
- Pierre, M., et al.
(författare)
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The XXL survey : First results and future
- 2017
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Ingår i: Astronomical Notes - Astronomische Nachrichten. - : Wiley-VCH Verlagsgesellschaft. - 0004-6337 .- 1521-3994. ; 338:2-3, s. 334-341
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Tidskriftsartikel (refereegranskat)abstract
- The XXL survey currently covers two 25 deg(2) patches with XMM observations of similar to 10 ks. We summarize the scientific results associated with the first release of the XXL dataset, which occurred in mid-2016. We review several arguments for increasing the survey depth to 40 ks during the next decade of XMM operations. X-ray (z < 2) cluster, (z < 4) active galactic nuclei (AGN), and cosmic background survey science will then benefit from an extraordinary data reservoir. This, combined with deep multi-lambda observations, will lead to solid standalone cosmological constraints and provide a wealth of information on the formation and evolution of AGN, clusters, and the X-ray background. In particular, it will offer a unique opportunity to pinpoint the z > 1 cluster density. It will eventually constitute a reference study and an ideal calibration field for the upcoming eROSITA and Euclid missions.
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| 3. |
- Horellou, Cathy, 1967, et al.
(författare)
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The XXL Survey: XXXIV. Double Irony in XXL-North: A tale of two radio galaxies in a supercluster at z = 0.14
- 2018
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 620
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Tidskriftsartikel (refereegranskat)abstract
- Aims. We show how the XXL multiwavelength survey can be used to shed light on radio galaxies and their environment. Methods. Two prominent radio galaxies were identified in a visual examination of the mosaic of XXL-North obtained with the Giant Metrewave Radio Telescope at 610 MHz. Counterparts were searched for in other bands. Spectroscopic redshifts from the GAMA database were used to identify clusters and/or groups of galaxies, estimate their masses with the caustic method, and quantify anisotropies in the surrounding galaxy distribution via a Fourier analysis. Results. Both radio galaxies are of FR I type and are hosted by early-type galaxies at a redshift of 0.138. The first radio source, named the Exemplar, has a physical extent of ∼400 kpc; it is located in the cluster XLSSC 112, which has a temperature of ∼2 keV, a total mass of ∼1014 Mo, and resides in an XXL supercluster with eight known members. The second source, named the Double Irony, is a giant radio galaxy with a total length of about 1.1 Mpc. Its core coincides with a cataloged point-like X-ray source, but no extended X-ray emission from a surrounding galaxy cluster was detected. However, from the optical data we determined that the host is the brightest galaxy in a group that is younger, less virialized, and less massive than the Exemplar's cluster. A friends-of-friends analysis showed that the Double Irony's group is a member of the same supercluster as the Exemplar. There are indications that the jets and plumes of the Double Irony have been deflected by gas associated with the surrounding galaxy distribution. Another overdensity of galaxies (the tenth) containing a radio galaxy was found to be associated with the supercluster. Conclusions. Radio Galaxies can be used to find galaxy clusters/groups that are below the current sensitivity of X-ray surveys.
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| 6. |
- Zorzan, M, et al.
(författare)
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Targeting the Regulatory Subunit R2Alpha of Protein Kinase A in Human Glioblastoma through shRNA-Expressing Lentiviral Vectors
- 2021
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Ingår i: Viruses. - : MDPI AG. - 1999-4915. ; 13:7
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Tidskriftsartikel (refereegranskat)abstract
- Glioblastoma is the most malignant and most common form of brain tumor, still today associated with a poor 14-months median survival from diagnosis. Protein kinase A, particularly its regulatory subunit R2Alpha, presents a typical intracellular distribution in glioblastoma cells compared to the healthy brain parenchyma and this peculiarity might be exploited in a therapeutic setting. In the present study, a third-generation lentiviral system for delivery of shRNA targeting the regulatory subunit R2Alpha of protein kinase A was developed. Generated lentiviral vectors are able to induce an efficient and stable downregulation of R2Alpha in different cellular models, including non-stem and stem-like glioblastoma cells. In addition, our data suggest a potential correlation between silencing of the regulatory subunit of protein kinase A and reduced viability of tumor cells, apparently due to a reduction in replication rate. Thus, our findings support the role of protein kinase A as a promising target for novel anti-glioma therapies.
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| 7. |
- Adami, C., et al.
(författare)
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The XXL Survey: XX. The 365 cluster catalogue
- 2018
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 620
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Tidskriftsartikel (refereegranskat)abstract
- Context. In the currently debated context of using clusters of galaxies as cosmological probes, the need for well-defined cluster samples is critical. Aims. The XXL Survey has been specifically designed to provide a well characterised sample of some 500 X-ray detected clusters suitable for cosmological studies. The main goal of present article is to make public and describe the properties of the cluster catalogue in its present state, as well as of associated catalogues of more specific objects such as super-clusters and fossil groups. Methods. Following from the publication of the hundred brightest XXL clusters, we now release a sample containing 365 clusters in total, down to a flux of a few 10-15 erg s-1 cm-2 in the [0.5-2] keV band and in a 1′ aperture. This release contains the complete subset of clusters for which the selection function is well determined plus all X-ray clusters which are, to date, spectroscopically confirmed. In this paper, we give the details of the follow-up observations and explain the procedure adopted to validate the cluster spectroscopic redshifts. Considering the whole XXL cluster sample, we have provided two types of selection, both complete in a particular sense: one based on flux-morphology criteria, and an alternative based on the [0.5-2] keV flux within 1 arcmin of the cluster centre. We have also provided X-ray temperature measurements for 80% of the clusters having a flux larger than 9 × 10-15 erg s-1 cm-2. Results. Our cluster sample extends from z ∼ 0 to z ∼ 1.2, with one cluster at z ∼ 2. Clusters were identified through a mean number of six spectroscopically confirmed cluster members. The largest number of confirmed spectroscopic members in a cluster is 41. Our updated luminosity function and luminosity-temperature relation are compatible with our previous determinations based on the 100 brightest clusters, but show smaller uncertainties. We also present an enlarged list of super-clusters and a sample of 18 possible fossil groups. Conclusions. This intermediate publication is the last before the final release of the complete XXL cluster catalogue when the ongoing C2 cluster spectroscopic follow-up is complete. It provides a unique inventory of medium-mass clusters over a 50 deg2 area out to z ∼ 1.
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| 8. |
- Guglielmo, V., et al.
(författare)
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The XXL Survey: XXX. Characterisation of the XLSSsC N01 supercluster and analysis of the galaxy stellar populations
- 2018
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 620
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Tidskriftsartikel (refereegranskat)abstract
- Context. Superclusters form from the largest enhancements in the primordial density perturbation field and extend for tens of Mpc, tracing the large-scale structure of the Universe. X-ray detections and systematic characterisations of superclusters and the properties of their galaxies have only been possible in the last few years. Aims. We characterise XLSSsC N01, a rich supercluster at z ∼ 0.3 detected in the XXL Survey, composed of X-ray clusters of different virial masses and X-ray luminosities. As one of the first studies on this topic, we investigate the stellar populations of galaxies in different environments in the supercluster region. Methods. We study a magnitude-limited (r ≤ 20) and a mass-limited sample (log(M ∗ Mo) ≥ 10.8) of galaxies in the virialised region and in the outskirts of 11 XLSSsC N01 clusters, in high-density field regions, and in the low-density field. We compute the stellar population properties of galaxies using spectral energy distribution (SED) and spectral fitting techniques, and study the dependence of star formation rates (SFR), colours, and stellar ages on environment. Results. For r ≤ 20, the fraction of star-forming/blue galaxies, computed either from the specific-SFR (sSFR) or rest-frame colour, shows depletion within the cluster virial radii, where the number of galaxies with log (sSFR/ yr-1) > -12 and with (g - r) restframe < 0.6 is lower than in the field. For log(M ∗ Mo) ≥ 10.8, no trends with environment emerge, as massive galaxies are mostly already passive in all environments. No differences among low- and high-density field members and cluster members emerge in the sSFR-mass relation in the mass-complete regime. Finally, the luminosity-weighted age-mass relation of the passive populations within cluster virial radii show signatures of recent environmental quenching. Conclusions. The study of luminous and massive galaxies in this supercluster shows that while environment has a prominent role in determining the fractions of star-forming/blue galaxies, its effects on the star formation activity in star-forming galaxies are negligible.
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| 9. |
- Baussan, E., et al.
(författare)
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A very intense neutrino super beam experiment for leptonic CP violation discovery based on the European spallation source linac
- 2014
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Ingår i: Nuclear Physics B. - : Elsevier BV. - 0550-3213 .- 1873-1562. ; 885, s. 127-149
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Tidskriftsartikel (refereegranskat)abstract
- Very intense neutrino beams and large neutrino detectors will be needed in order to enable the discovery of CP violation in the leptonic sector. We propose to use the proton linac of the European Spoliation Source currently under construction in Lund, Sweden, to deliver, in parallel with the spoliation neutron production, a very intense, cost effective and high performance neutrino beam. The baseline program for the European Spoliation Source linac is that it will be fully operational at 5 MW average power by 2022, producing 2 GeV 2.86 ms long proton pulses at a rate of 14 Hz. Our proposal is to upgrade the linac to 10 MW average power and 28 Hz, producing 14 pulses/s for neutron production and 14 pulses/s for neutrino production. Furthermore, because of the high current required in the pulsed neutrino horn, the length of the pulses used for neutrino production needs to be compressed to a few mu s with the aid of an accumulator ring. A long baseline experiment using this Super Beam and a megaton underground Water Cherenkov detector located in existing mines 300-600 km from Lund will make it possible to discover leptonic CP violation at 5 sigma significance level in up to 50% of the leptonic Dirac CP-violating phase range. This experiment could also determine the neutrino mass hierarchy at a significance level of more than 3 sigma if this issue will not already have been settled by other experiments by then. The mass hierarchy performance could be increased by combining the neutrino beam results with those obtained from atmospheric neutrinos detected by the same large volume detector. This detector will also be used to measure the proton lifetime, detect cosmological neutrinos and neutrinos from supernova explosions. Results on the sensitivity to leptonic CP violation and the neutrino mass hierarchy are presented.
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| 10. |
- Caretta, Martina Angela, 1986-, et al.
(författare)
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A reflexive analysis on field knowledge production and academic labor during PhD studies
- 2015
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The multitasking nature of academic labor has become an increasingly essential part of PhD studies. Teaching, competition for funding, international networking and publishing in high impact journals are expected and encouraged. This situation becomes even more complex when a doctoral candidate needs to perform fieldwork, as it is common in geography. In this paper, the gendered nature of fieldwork is analyzed through the autobiographical accounts of two young female doctoral students in human geography carrying out field research in the global south. As opposed to the positivistic ideal of scientific objectivity, the results show that embodiment and wellbeing play a pivotal role in influencing the course of fieldwork. Hence, we examine the everyday dimensions of field research both during pre-fieldwork planning and post-fieldwork. Lastly, we discuss current neoliberal prerequisites to secure an academic career and what they imply for researchers' lives.
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