| 1. |
- Carlsson, Arvid, 1923, et al.
(författare)
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Interactions between monoamines, glutamate, and GABA in schizophrenia: new evidence
- 2001
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Ingår i: Annu Rev Pharmacol Toxicol. - 0362-1642. ; 41, s. 237-60
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Forskningsöversikt (refereegranskat)abstract
- In spite of its proven heuristic value, the dopamine hypothesis of schizophrenia is now yielding to a multifactorial view, in which the other monoamines as well as glutamate and GABA are included, with a focus on neurotransmitter interactions in complex neurocircuits. The primary lesion(s) in schizophrenia does not necessarily involve any of these neurotransmitters directly but could deal with a more general defect, such as a faulty connectivity of developmental origin. Nevertheless, a precise identification of neurotransmitter aberrations in schizophrenia will probably provide clues for a better understanding of the disease and for the development of new treatment and prevention strategies.
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| 2. |
- Carlsson, Maria L., 1959, et al.
(författare)
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The 5-HT2A receptor antagonist M100907 is more effective in counteracting NMDA antagonist- than dopamine agonist-induced hyperactivity in mice
- 1999
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Ingår i: J Neural Transm. - 0300-9564. ; 106:2, s. 123-9
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Tidskriftsartikel (refereegranskat)abstract
- The purpose of the present study was to compare the effectiveness of the selective 5-HT2A antagonist M100907 in different psychosis models. The classical neuroleptic haloperidol was used as reference compound. Two hyperdopaminergia and two hypoglutamatergia mouse models were used. Hyperdopaminergia was produced by the DA releaser d-amphetamine or the DA uptake inhibitor GBR 12909. Hypoglutamatergia was produced by the un-competitive NMDA receptor antagonist MK-801 or the competitive NMDA receptor antagonist D-CPPene. M100907 was found to counteract the locomotor stimulant effects of the NMDA receptor antagonists MK-801 and D-CPPene, but spontaneous locomotion, d-amphetamine- and GBR-12909-induced hyperactivity were not significantly affected. Haloperidol, on the other hand, antagonized both NMDA antagonist- and DA agonist-induced hyperactivity, as well as spontaneous locomotion in the highest dose used. Based on the present and previous results we draw the conclusion that 5-HT2A receptor antagonists are particularly effective against behavioural anomalies resulting from hypoglutamatergia of various origins. The clinical implications of our results and conclusions would be that a 5-HT2A receptor antagonist, due to i a the low side effect liability, could be the preferable treatment strategy in various disorders associated with hypoglutamatergia; such conditions might include schizophrenia, childhood autism and dementia disorders.
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| 3. |
- Carlsson, Bo, et al.
(författare)
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Idrott i förändring, revisited och en idrottsvetenskaplig profilering
- 2009
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Ingår i: Svensk Idrottsforskning. - 1103-4629. ; 18:3, s. 4-9
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Svensk idrottsforskning, 2005, nr. 3 var ett temanummer där vi fick den glädjande möjligheten att presentera den idrottsvetenskapliga forskningen vid Malmö högskola.1 Det har gått några år sedan dess och verksamheten har växt och erhållit en fastare struktur. Dessutom har forskningen blivit allt mer profilerad mot det som vi benämner som ”idrott i förändring”, vilket i grunden är en tydligt och strategiskt inriktad samhälls- och kulturvetenskaplig idrottsvetenskap. Vi ska i detta temanummer behandla ett antal idrottsvetenskapliga problem som anknyter till vår forskning. Vi har därför valt att lyfta nya forskare och/eller nya forskningsprojekt, som inte medverkade i 2005 års temanummer. Texterna kommer att handla om folkhemshästen, drömmar bland fotbollens ungdomsproffs, Parkour, idrottens betydelse för det civila samhället, idrottsdidaktiska utmaningar, Corporate Social Responsibility, idrottens arbetsmarknad och dess professionalisering, barnidrott i regi av ”Stadium Sports Camp”, samt rättvise- och kravmärkt idrott. Vi hoppas att dessa texter ska ge en liten, men dock rättvis, bild av våra forskningsintressen.
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| 4. |
- Carlsson, Bo, et al.
(författare)
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The development of youth sport in Sweden
- 2011
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Ingår i: Routledge handbook of sports development. - : Routledge. - 9780415479967 ; , s. 160-172
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Bokkapitel (refereegranskat)abstract
- In the chapter the development of children and youth sport in Sweden in the 20th century is explored. The definition of sport covers both sport in school and other sport activities.
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| 5. |
- Carlsson, Bo, et al.
(författare)
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The development of youth sport in Sweden
- 2013
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Ingår i: Routledge handbook of sports development. - : Routledge. - 9780415479950 ; , s. 160-172
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Bokkapitel (refereegranskat)abstract
- This book identifies and defines the core functions of sports development, exploring the interface between sports development and cognate fields such as education, coaching, community welfare and policy.
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| 6. |
- Carlsson, Bo, et al.
(författare)
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The position and relevance of sport studies : an introduction
- 2014
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Ingår i: Sport in Society. - : Taylor & Francis. - 1743-0437 .- 1743-0445. ; 17, s. 1225-1233
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Tidskriftsartikel (refereegranskat)abstract
- This volume will tactically put the stubborn challenge of defining sport in ‘intellectual brackets’ and instead reflect on the position and relevance of sport science – of studying and analysing sport
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| 7. |
- Carlsson, Fredrik, 1968, et al.
(författare)
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Economic Freedom and Growth:Decomposing the Effects
- 2001
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Most studies of the relation between economic freedom and growth of GDP have found a positive relation. One problem in this area is the choice of economic freedom measure. A single measure does notreflect the complex economic environment and a highly aggregated index makes it difficult to draw policy conclusions. In this paper we investigate what specific types of economic freedom measures that are important for growth. The robustness of the results is carefully analysed since the potential problem with multicollinearity is one of the negative effects of decomposing an index. The results show that economic freedom does matter for growth. This does not mean that increasing economic freedom, definedin general terms, is good for economic growth since some of the categories in the index are insignificant and some of the significant variables have negative effects.
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| 8. |
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| 9. |
- Carlsson, Fredrik, 1968, et al.
(författare)
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The Effects of Economic and Political Freedom on CO2 Emissions
- 2003
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- In this paper we investigate the effects of political and economic freedom on CO2 emissions. As far as we know this is the first cross-country study of the relationship between economic freedom and environmental quality. Economic freedom is measured in several ways. We find that increased price stability and legal structure decrease emissions in countries with a small industry share of GDP, but increases emissions in countries with a large industry share of GDP. The decreasing effect from increased use of market is significant but non-robust, and increased freedom to trade does not have any significant effect. The effect of political freedom on CO2 emissions is insignificant, most probably since CO2 emissions is a global environmental problem and hence subject to free-riding by the individual countries.
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| 10. |
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