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| 2. |
- Tona, Olgerta, et al.
(författare)
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The Impact of the Organizing Vision on Mobile BI Adoption
- 2014
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Ingår i: DSS 2.0 – Supporting Decision Making with New Technologies. - 0922-6389. - 9781614993988 ; 261, s. 303-313
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Konferensbidrag (refereegranskat)abstract
- Mobile Business Intelligence (m-BI) enhances the capabilities of organizations to take decisions 'on-the-move'. M-BI emerged as an extension of BI and many companies have or are considering implementing it. Being an innovation, m-BI reflects an organizing vision, created by a broad community, which is prominent during the comprehension process of this innovation. Little is known how the organizing vision affects the decision to adopt a certain innovation, and moreover these studies are completely lacking within the m-BI area. A qualitative approach has been embraced and interviews with different organizations that have already decided to adopt m-BI have been conducted. This study revealed that industrial research reports, vendors marketing campaigns and success stories produced by the collaboration among vendors, analysts, journalist and early adopters have a strong influence on the early phases of the organizational decision-making process to adopt m-BI. Increasing internal and external legitimacy, reducing the risk to be left behind, gaining competitive advantage, following the footsteps of high-performing companies, increasing their prestige and reputation, are the main reasons for why organizations may start the decision-making process to adopt m-BI; all this under the umbrella of the organizing vision.
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| 3. |
- Carlsson, Sven G., 1935, et al.
(författare)
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The effect of amphetamine and L-dopa on tetrabenazine-induced suppression of intracranial self-stimulation in the rat.
- 1977
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Ingår i: Scandinavian journal of psychology. - 0036-5564. ; 18:2, s. 157-60
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Tidskriftsartikel (refereegranskat)abstract
- The administration of d-amphetamine sulphate resulted in a restoration of intracranial self-stimulation (ICSS) suppressed by tetrabenazine (TBZ). A dose-dependent increase in the rate of ICSS was seen after L-dopa in animals pretreated with TBZ. d-Amhetamine is believed to act by facilitating the nerve-impulse induced release of central catecholamines (CA) whereas the blockage of the granular uptake-storage mechanism by TBZ will prevent the storage of CA formed from the administrated L-dopa and thereby interfere with their release by nerve-impulses. Thus, in the latter case, an activation of central CA receptors in all probability will be due to a dose-dependent diffusion of CA from nerve terminals. It is suggested that the failure to completely antagonize the TBZ-induced suppression of behaviour by L-dopa is due to the fact that a direct activation, independent of the nerve-impulse flow, of central CA receptors easily results in an overstimulation and a reduced specificity in behaviour.
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| 4. |
- Dahlström, Lars, et al.
(författare)
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Comparison of effects of electromyographic biofeedback and occlusal splint therapy on mandibular dysfunction.
- 1982
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Ingår i: Scandinavian journal of dental research. - 0029-845X. ; 90:2, s. 151-6
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Tidskriftsartikel (refereegranskat)abstract
- In order to evaluate and compare the effects of biofeedback and occlusal splint therapy on mandibular dysfunction, 30 patients were randomly divided into two treatment groups. The patients were women aged 20--40 years without any obvious organic reasons for their symptoms. There were no significant differences between the two groups before the start of treatment in respect of signs and symptoms of mandibular dysfunction. One group used full coverage splints at night for 6 weeks. The other group received biofeedback training up to six times, 30 min per session. One month after completion of the therapy the patients were re-examined. Both groups showed a significant reduction in symptoms, both subjectively and clinically. No significant differences between the groups were found. The two treatments were thus equally effective in the short-term perspective in patients with signs and symptoms of mandibular dysfunction.
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| 5. |
- Dahlström, Lars, et al.
(författare)
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Variability in electromyographic surface recordings of the human masseter muscle.
- 1989
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Ingår i: Electromyography and clinical neurophysiology. - 0301-150X. ; 29:2, s. 105-8
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Tidskriftsartikel (refereegranskat)abstract
- Serial registrations of integrated unilateral surface masseter EMG were performed in eight healthy subjects in the rest position, during controlled gentle biting and during maximal clenching at five different sessions in order to analyse the variability. The recording conditions were standardised. The EMG activity for the group did not differ significantly between the sessions at any level but individual variations were great in the rest position both within and between days. Good consistency was found at controlled force levels. Temporally stable measurements of masseter activity which permit quantitative comparisons thus seem possible.
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| 6. |
- Sjöström, Lars, et al.
(författare)
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Bariatric surgery and long-term cardiovascular events.
- 2012
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Ingår i: JAMA : the journal of the American Medical Association. - : American Medical Association (AMA). - 1538-3598. ; 307:1, s. 56-65
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Tidskriftsartikel (refereegranskat)abstract
- Obesity is a risk factor for cardiovascular events. Weight loss might protect against cardiovascular events, but solid evidence is lacking.
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| 7. |
- Sjöström, Lars, et al.
(författare)
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Effects of bariatric surgery on cancer incidence in obese patients in Sweden (Swedish Obese Subjects Study): a prospective, controlled intervention trial.
- 2009
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Ingår i: The lancet oncology. - 1474-5488. ; 10:7, s. 653-62
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Obesity is a risk factor for cancer. Intentional weight loss in the obese might protect against malignancy, but evidence is limited. To our knowledge, the Swedish Obese Subjects (SOS) study is the first intervention trial in the obese population to provide prospective, controlled cancer-incidence data. METHODS: The SOS study started in 1987 and involved 2010 obese patients (body-mass index [BMI] >or=34 kg/m(2) in men, and >or=38 kg/m(2) in women) who underwent bariatric surgery and 2037 contemporaneously matched obese controls, who received conventional treatment. While the main endpoint of SOS was overall mortality, the main outcome of this exploratory report was cancer incidence until Dec 31, 2005. Cancer follow-up rate was 99.9% and the median follow-up time was 10.9 years (range 0-18.1 years). FINDINGS: Bariatric surgery resulted in a sustained mean weight reduction of 19.9 kg (SD 15.6 kg) over 10 years, whereas the mean weight change in controls was a gain of 1.3 kg (SD 13.7 kg). The number of first-time cancers after inclusion was lower in the surgery group (n=117) than in the control group (n=169; HR 0.67, 95% CI 0.53-0.85, p=0.0009). The sex-treatment interaction p value was 0.054. In women, the number of first-time cancers after inclusion was lower in the surgery group (n=79) than in the control group (n=130; HR 0.58, 0.44-0.77; p=0.0001), whereas there was no effect of surgery in men (38 in the surgery group vs 39 in the control group; HR 0.97, 0.62-1.52; p=0.90). Similar results were obtained after exclusion of all cancer cases during the first 3 years of the intervention. INTERPRETATION: Bariatric surgery was associated with reduced cancer incidence in obese women but not in obese men. FUNDING: Swedish Research Council, Swedish Foundation for Strategic Research, Swedish Federal Government under the LUA/ALF agreement, Hoffmann La Roche, Cederoths, AstraZeneca, Sanofi-Aventis, Ethicon Endosurgery.
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| 8. |
- Sjöström, Lars, et al.
(författare)
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Effects of bariatric surgery on mortality in Swedish obese subjects.
- 2007
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Ingår i: The New England journal of medicine. - 1533-4406. ; 357:8, s. 741-52
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Obesity is associated with increased mortality. Weight loss improves cardiovascular risk factors, but no prospective interventional studies have reported whether weight loss decreases overall mortality. In fact, many observational studies suggest that weight reduction is associated with increased mortality. METHODS: The prospective, controlled Swedish Obese Subjects study involved 4047 obese subjects. Of these subjects, 2010 underwent bariatric surgery (surgery group) and 2037 received conventional treatment (matched control group). We report on overall mortality during an average of 10.9 years of follow-up. At the time of the analysis (November 1, 2005), vital status was known for all but three subjects (follow-up rate, 99.9%). RESULTS: The average weight change in control subjects was less than +/-2% during the period of up to 15 years during which weights were recorded. Maximum weight losses in the surgical subgroups were observed after 1 to 2 years: gastric bypass, 32%; vertical-banded gastroplasty, 25%; and banding, 20%. After 10 years, the weight losses from baseline were stabilized at 25%, 16%, and 14%, respectively. There were 129 deaths in the control group and 101 deaths in the surgery group. The unadjusted overall hazard ratio was 0.76 in the surgery group (P=0.04), as compared with the control group, and the hazard ratio adjusted for sex, age, and risk factors was 0.71 (P=0.01). The most common causes of death were myocardial infarction (control group, 25 subjects; surgery group, 13 subjects) and cancer (control group, 47; surgery group, 29). CONCLUSIONS: Bariatric surgery for severe obesity is associated with long-term weight loss and decreased overall mortality.
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| 9. |
- Smith, Gudmund, et al.
(författare)
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Dialog hösten 2009
- 2010
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Ingår i: Kreativitet och mognad : festskrift tillägnad Professor Gudmund Smith på 90-årsdagen den 29 januari 2010. - 9789197871808 ; , s. 151-158
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Bokkapitel (refereegranskat)
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| 10. |
- Starck, Göran, et al.
(författare)
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A 1H magnetic resonance spectroscopy study in adults with obsessive compulsive disorder: relationship between metabolite concentrations and symptom severity.
- 2008
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Ingår i: Journal of neural transmission (Vienna, Austria : 1996). - : Springer Science and Business Media LLC. - 0300-9564 .- 1435-1463. ; 115:7, s. 1051-62
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Tidskriftsartikel (refereegranskat)abstract
- 1H magnetic resonance spectroscopy (1H MRS) studies exploring brain metabolites, especially glutamine + glutamate (Glx), in obsessive compulsive disorder (OCD) are of vital interest for trying to understand more about the pathophysiology of OCD. Therefore, we conducted the present 1H MRS study with the aims of (1) comparing MRS metabolites in a group of adult patients with OCD and a group of healthy controls, and (2) examining the relationship between MRS metabolite concentrations and symptom severity in the patient group. Three brain regions were studied, the right caudate nucleus, the anterior gyrus cinguli and the occipital cortex bilaterally. Since multivariate analysis is a highly useful tool for extraction of 1H MRS data, we applied principal component analysis (PCA) and partial least square projection to latent structures (PLS) to the MRS data. PLS disclosed a strong relationship between several of the metabolites and OCD symptom severity, as measured with Yale-Brown obsessive-compulsive scale (YBOCS): the YBOCS score was found to be positively correlated to caudate creatine, Glx, glutamate, and choline compounds as well as occipital cortex myoinositol, and negatively correlated to occipital cortex Glx. The negative correlation between occipital cortex Glx and YBOCS was the most impressive. PCA did not reveal any tendency for a separation between the patients with OCD and controls with respect to MRS metabolites. The results are discussed in relation to corticostriatothalamocortical feedback and previous observations of poor visuospatial ability in OCD.
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