| 1. |
- Agardh, Carl-David, et al.
(författare)
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Optic disc swelling in an insulin-dependent diabetic. A result of drastic improvement of glucose control?
- 1988
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Ingår i: Acta Ophthalmologica. - 0001-639X. ; 66:2, s. 206-209
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Tidskriftsartikel (refereegranskat)abstract
- Rapid improvement of glucose control in diabetics may cause a transient progression of ischemic retinopathy. We report a transient bilateral acute asymptomatic optic disc swelling associated with rapid improvement of metabolic control in a male Type I diabetic. It is d, suggested that the optic disc swelling could be caused n of by a rapid near-normal normalization of the blood glucose.
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| 2. |
- Agardh, Elisabet, et al.
(författare)
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Retinopathy and nephropathy in insulin-dependent diabetics: an inconsistent relationship?
- 1987
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Ingår i: Diabetic Medicine. - 1464-5491. ; 4:3, s. 248-250
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Tidskriftsartikel (refereegranskat)abstract
- The association between retinopathy and nephropathy was investigated in a retrospective study of 52 insulin-dependent diabetics with preproliferative or proliferative retinopathy and in 48 patients without or with background retinopathy. The duration of diabetes was 23.2 +/- 1.0 years (mean +/- SEM) and 22.0 +/- 1.2 years in the two groups. Patients in the retinopathy group showed a higher frequency of detectable nephropathy and were more often treated with antihypertensive drugs. However, a high proportion (35%) of patients with proliferative retinopathy did not show any detectable signs of nephropathy. Furthermore, nephropathy did not seem to develop in patients with retinopathy during an observation period of up to 9 years. The data suggest that the factors underlying the development of retinal and renal microangiopathy might be of different origin.
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| 3. |
- Agardh, Elisabet, et al.
(författare)
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The importance of early diagnosis of treatable diabetic retinopathy for the four-year visual outcome in older-onset diabetes mellitus
- 1996
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Ingår i: Acta Ophthalmologica Scandinavica. - 1395-3907. ; 74:2, s. 166-170
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Tidskriftsartikel (refereegranskat)abstract
- The four-year visual outcome was retrospectively studied in patients with older-onset diabetes mellitus and diabetic retinopathy in need of laser treatment. Visual acuity in 53 patients examined by ophthalmologists who referred the patients for an evaluation of retinopathy before laser treatment, was compared to that of 47 patients examined by ophthalmologists who also performed the photocoagulation. The number of eyes that became blind (visual acuity < or = 6/60) during the four-year period was higher (23/90 vs 9/91; p < 0.01) among referred patients, whereas the number of retinal examinations per patient during the three-year period prior to laser treatment did not differ between the two groups. Among referred patients, 13% had not been ophthalmologically examined before the treatment-requiring retinopathy was found. Corresponding figure for those examined at the laser centre was 23%. Severe macular oedema in regularly examined patients was more common among referred patients (9/30 vs 1/32; p < 0.01). The results indicate that screening for diabetic retinopathy in older-onset diabetes was not performed satisfactorily. In addition, laser treatment was delayed in older-onset diabetic patients controlled by ophthalmologists who referred patients for photocoagulation, resulting in an increased incidence of legally blind eyes. The study also stresses the importance of carrying out knowledge of when and how to diagnose early sight-threatening diabetic retinopathy to ophthalmologists referring patients for laser treatment.
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