| 1. |
- Kanai, M, et al.
(författare)
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- 2023
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swepub:Mat__t
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| 2. |
- Niemi, MEK, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 3. |
- Dewey, C., et al.
(författare)
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Accurate Identification of Novel Human Genes Through Simultaneous Gene Prediction in Human, Mouse and Rat
- 2004
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Ingår i: Genome Research. - 1088-9051 .- 1549-5469. ; 14:4, s. 661-664
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Tidskriftsartikel (refereegranskat)abstract
- We describe a new method for simultaneously identifying novel homologous genes with identical structure in the human, mouse, and rat genomes by combining pairwise predictions made with the SLAM gene-finding program. Using this method, we found 3698 gene triples in the human, mouse, and rat genomes which are predicted with exactly the same gene structure. We show, both computationally and experimentally, that the introns of these triples are predicted accurately as compared with the introns of other ab initio gene prediction sets. Computationally, we compared the introns of these gene triples, as well as those from other ab initio gene finders, with known intron annotations. We show that a unique property of SLAM, namely that it predicts gene structures simultaneously in two organisms, is key to producing sets of predictions that are highly accurate in intron structure when combined with other programs. Experimentally, we performed reverse transcription-polymerase chain reaction (RT-PCR) in both the human and rat to test the exon pairs flanking introns from a subset of the gene triples for which the human gene had not been previously identified. By performing RT-PCR on orthologous introns in both the human and rat genomes, we additionally explore the validity of using RT-PCR as a method for confirming gene predictions.
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| 4. |
- Diligent, O, et al.
(författare)
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The low-frequency reflection and scattering of the S0 Lamb mode from a circular through-thickness hole in a plate: Finite Element, analytical and experimental studies
- 2002
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Ingår i: Journal of the Acoustical Society of America. - : Acoustical Society of America (ASA). - 1520-8524 .- 0001-4966. ; 112:6, s. 2589-2601
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Tidskriftsartikel (refereegranskat)abstract
- A study of the interaction of the S0 Lamb wave with a circular through-thickness hole in a plate is presented. The study is limited to the nondispersive frequency range of this wave, in which the distributions of stress and displacement are simple. This allows a Finite Element analysis to be undertaken using a two-dimensional membrane discretization. Predictions of the direct reflection of the S0 mode and the lateral scattering of the SH0 mode are made for a range of diameters of the hole. At the same time, an analytical solution based on modal superposition is developed, and this is also used to predict the reflection and scattering coefficients. Both sets of predictions are validated by experimental measurements. It is found that the trends of the reflection coefficients for different hole diameters, frequencies and distances from the hole satisfy a simple normalization. On a detailed scale, the functions exhibit undulations which are shown to result from the interference of the direct reflection with secondary reflections which arrive slightly later.
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| 5. |
- Rydén, Nils, et al.
(författare)
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Non-contact surface wave scanning of pavements using a rolling microphone array
- 2008
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Ingår i: Review of Progress in Quantitative Nondestructive Evaluation, vol 27A and 27B. - : AIP. - 0094-243X .- 1551-7616. ; 975, s. 1328-1332
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Konferensbidrag (refereegranskat)abstract
- We present experiments with a rolling multichannel microphone array where measurements can be taken continuously while moving. Leaky air-coupled surface waves are measured with ordinary non-directional audio microphones. Results show that microphones can be successfully used to produce a realistic phase velocity spectrum even while moving along the surface. The paper presents some theoretical background along with initial experimental results using the moving microphone array.
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| 6. |
- Rydén, Nils, et al.
(författare)
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Noncontact surface wave testing of pavements using microphones.
- 2008
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Ingår i: Journal of the Acoustical Society of America. - : Acoustical Society of America (ASA). - 1520-8524 .- 0001-4966. ; 124:4
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Tidskriftsartikel (refereegranskat)abstract
- Pavements are constructed using several layers of materials, and their durability depends mainly on the stiffness modulus and thickness of these strata. Surface wave testing is an effective tool to measure the stiffness and thickness of pavement layers. However, measurements are still based on spot testing with fixed receivers and source. The typical large size of pavements and the cost of closing down roads to make stationary testing makes these measurements impractical. We present experiments where a multichannel array of microphones and an automatic source are attached on a small trolley so that measurements can be taken almost continuously while moving. Measurements on asphalt or concrete pavement layers are based on supersonic leaky air-coupled surface waves. We also demonstrate that the same approach can be applied to softer granular pavement layers utilizing the seismic-to-acoustic coupling in poroelastic materials. Results show that microphones can be successfully used to measure correct surface wave dispersion curves even while moving along the surface. This opens up the possibility for faster on-the-fly surface wave testing of pavement layers since surface contact is no longer required. The theoretical background along with experimental results of the application to nondestructive testing of pavements will be presented.
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