| 1. |
- Dhage, S. R., et al.
(författare)
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CIGS absorber layer by single-step non-vacuum intense pulsed light treatment of inkjet-printed film
- 2014
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Ingår i: 2014 IEEE 40th Photovoltaic Specialist Conference, PVSC 2014. ; , s. 1607-1610
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Konferensbidrag (refereegranskat)abstract
- Non-vacuum processes are of great interest for development of low-cost chalcopyrite-based photovoltaic technologies. Apart from the expensive vacuum-based routes that are widely adopted, another negative feature of the popularly employed methods is the need for selenization treatment, which significantly impacts the microstructure of the absorber layer and, in turn, also determines the performance of the device. A novel process for preparation of Cu(In0.7Ga0.3)Se2 (CIGS) films from an ink constituted of CIGS nanoparticles utilizing a convenient intense pulsed light (IPL) treatment is investigated in the present study. Initially, a thorough optimization of ink formulation variables was carried out in order to make the CIGS ink suitable for ink jet printing. The home-made CIGS ink, comprising CIGS nanoparticles with appropriate additives, was then successfully deposited with a print head having 256 nozzles on Mo coated soda lime glass substrate. Subsequently, IPL was used to treat the printed CIGS ink. Post IPL treatment, a CIGS film retaining the chalcopyrite structure even after melting and recrystallization, with no secondary phase formation, was realized. The phase constitution, thickness and morphology of prepared films were determined using X-ray diffraction (XRD), X-ray fluorescence spectroscopy (XRF) and field emission scanning electron microscopy (FESEM). The above non-vacuum, room temperature process not requiring any selenization treatment can have important implications in realization of cost-effective CIGS absorber layers.
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| 2. |
- Mattick, J. S., et al.
(författare)
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Long non-coding RNAs: definitions, functions, challenges and recommendations
- 2023
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Ingår i: Nature Reviews Molecular Cell Biology. - : Springer Science and Business Media LLC. - 1471-0072 .- 1471-0080. ; 24:6, s. 430-447
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Tidskriftsartikel (refereegranskat)abstract
- Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II and Pol III transcribed RNAs, and RNAs from processed introns. The various functions of lncRNAs and their many isoforms and interleaved relationships with other genes make lncRNA classification and annotation difficult. Most lncRNAs evolve more rapidly than protein-coding sequences, are cell type specific and regulate many aspects of cell differentiation and development and other physiological processes. Many lncRNAs associate with chromatin-modifying complexes, are transcribed from enhancers and nucleate phase separation of nuclear condensates and domains, indicating an intimate link between lncRNA expression and the spatial control of gene expression during development. lncRNAs also have important roles in the cytoplasm and beyond, including in the regulation of translation, metabolism and signalling. lncRNAs often have a modular structure and are rich in repeats, which are increasingly being shown to be relevant to their function. In this Consensus Statement, we address the definition and nomenclature of lncRNAs and their conservation, expression, phenotypic visibility, structure and functions. We also discuss research challenges and provide recommendations to advance the understanding of the roles of lncRNAs in development, cell biology and disease.
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| 3. |
- Ali, S., et al.
(författare)
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Influence of the water–sediment interaction on the major ions chemistry and fluoride pollution in groundwater of the Older Alluvial Plains of Delhi, India
- 2021
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Ingår i: Journal of Earth System Science. - : Springer Nature. - 2347-4327 .- 0973-774X. ; 130:2
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Tidskriftsartikel (refereegranskat)abstract
- Fluoride (F–) pollution in groundwater of the Older Alluvial Plain (OAP) of Delhi has been reported as a major problem. About 34% of the groundwater samples collected for this study had F– level beyond the permissible limit; with F– concentration in the range of 0.14–3.15 mg/L (average 1.20 mg/L). In this context, this article for the first time attempts on the genesis of major ions chemistry and F– pollution in groundwater of OAP Delhi by going beyond the statistical analysis to sediment geochemistry, chemical weathering processes and understanding of the processes using stable environmental isotopes (2H and 18O). The XRD of the OAP sediments revealed the dominance of fluor-biotite, albite, calcite, quartz, and chlorite. Whereas, the separated clay revealed the dominance of chlorite, kaolinite, and illite minerals. The saturation index (SI) values indicated that the groundwater chemistry is in the process of further F– enrichment by way of sediment groundwater interaction. With the given mineralogy of the sediments, the dominance of major ions like Na+, K+, Mg2+, Ca2+, Cl– and F– has been attributed to chemical weathering of biotites, phlogopites, albite, and calcite during sediment–water interaction. While the dominance of SO42– has been attributed to anthropogenic sources and confirmed by its association with heavier stable isotopes of hydrogen (δ2H: −50.44 to −40.02‰) and oxygen (δ18O: −7.19 to −5.62‰) indicating evaporative enrichment during isotopic fractionation.
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| 4. |
- Ali, S., et al.
(författare)
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Elevated fluoride in groundwater of Siwani Block, Western Haryana, India : A potential concern for sustainable water supplies for drinking and irrigation
- 2018
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Ingår i: Groundwater for Sustainable Development. - : Elsevier BV. - 2352-801X. ; 7, s. 410-420
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Tidskriftsartikel (refereegranskat)abstract
- Groundwater pollution is a serious health concern in north-western India. In this study, we have reported very high concentration of fluoride i.e. 18.5 and 16.6 mg/l from Sainiwas locality in Siwani block of Bhiwani district, Haryana, India. The values are much higher than the permissible limit set by WHO and BIS. The evapotranspiration in the area leads to Ca2+ precipitation, which allows an increase in F- content in the groundwater. In addition, the replacement of hydroxyl of secondary clay mineral under alkaline condition is responsible for release of F-. In absence of alternative source, the fluoride polluted groundwater in some of these localities is also used for drinking. Further, the suitability of groundwater for irrigation is also evaluated by various parameters such as Sodium Adsorption Ratio (SAR), Sodium Percentage (Na%), Kelly's Ratio (KR), Magnesium Hazard (MH) and Residual Sodium Carbonate (RSC). It emerges out that in a few localities, groundwater is not suitable for irrigation and with respect to Magnesium Hazard (MH) almost all samples are unsuitable for irrigation. This article highlights groundwater quality of Siwani block in Haryana and proposes for immediate remedial measures.
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| 5. |
- Ma, Haixia, et al.
(författare)
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The transcription factor Foxp1 regulates aerobic glycolysis in adipocytes and myocytes
- 2023
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Ingår i: Journal of Biological Chemistry. - 0021-9258 .- 1083-351X. ; 299:6
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Tidskriftsartikel (refereegranskat)abstract
- In recent years, lactate has been recognized as an important circulating energy substrate rather than only a dead-end metabolic waste product generated during glucose oxidation at low levels of oxygen. The term "aerobic glycolysis" has been coined to denote increased glucose uptake and lactate pro-duction despite normal oxygen levels and functional mito-chondria. Hence, in "aerobic glycolysis," lactate production is a metabolic choice, whereas in "anaerobic glycolysis," it is a metabolic necessity based on inadequate levels of oxygen. Interestingly, lactate can be taken up by cells and oxidized to pyruvate and thus constitutes a source of pyruvate that is in-dependent of insulin. Here, we show that the transcription factor Foxp1 regulates glucose uptake and lactate production in adipocytes and myocytes. Overexpression of Foxp1 leads to increased glucose uptake and lactate production. In addition, protein levels of several enzymes in the glycolytic pathway are upregulated, such as hexokinase 2, phosphofructokinase, aldolase, and lactate dehydrogenase. Using chromatin immu-noprecipitation and real-time quantitative PCR assays, we demonstrate that Foxp1 directly interacts with promoter consensus cis-elements that regulate expression of several of these target genes. Conversely, knockdown of Foxp1 suppresses these enzyme levels and lowers glucose uptake and lactate production. Moreover, mice with a targeted deletion of Foxp1 in muscle display systemic glucose intolerance with decreased muscle glucose uptake. In primary human adipocytes with induced expression of Foxp1, we find increased glycolysis and glycolytic capacity. Our results indicate Foxp1 may play an important role as a regulator of aerobic glycolysis in adipose tissue and muscle.
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| 10. |
- Kumar, A. Naresh, et al.
(författare)
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Upgrading the value of anaerobic fermentation via renewable chemicals production : A sustainable integration for circular bioeconomy
- 2022
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Ingår i: Science of the Total Environment. - : Elsevier. - 0048-9697 .- 1879-1026. ; 806, part 1
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Forskningsöversikt (refereegranskat)abstract
- The single bioprocess approach has certain limitations in terms of process efficiency, product synthesis, and effective resource utilization. Integrated or combined bioprocessing maximizes resource recovery and creates a novel platform to establish sustainable biorefineries. Anaerobic fermentation (AF) is a well-established process for the transformation of organic waste into biogas; conversely, biogas CO2 separation is a challenging and cost-effective process. Biological fixation of CO2 for succinic acid (SA) mitigates CO2 separation issues and produces commercially important renewable chemicals. Additionally, utilizing digestate rich in volatile fatty acid (VFA) to produce medium-chain fatty acids (MCFAs) creates a novel integrated platform by utilizing residual organic metabolites. The present review encapsulates the advantages and limitations of AF along with biogas CO2 fixation for SA and digestate rich in VFA utilization for MCFA in a closed-loop approach. Biomethane and biohydrogen process CO2 utilization for SA production is cohesively deliberated along with the role of biohydrogen as an alternative reducing agent to augment SA yields. Similarly, MCFA production using VFA as a substrate and function of electron donors namely ethanol, lactate, and hydrogen are comprehensively discussed. A road map to establish the fermentative biorefinery approach in the framework of AF integrated sustainable bioprocess development is deliberated along with limitations and factors influencing for techno-economic analysis. The discussed integrated approach significantly contributes to promote the circular bioeconomy by establishing carbon-neutral processes in accord with sustainable development goals.
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