| 1. |
- Sliz, E., et al.
(författare)
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Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata
- 2023
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Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 14:1
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Tidskriftsartikel (refereegranskat)abstract
- Uterine leiomyomata (UL) are the most common tumours of the female genital tract and the primary cause of surgical removal of the uterus. Genetic factors contribute to UL susceptibility. To add understanding to the heritable genetic risk factors, we conduct a genome-wide association study (GWAS) of UL in up to 426,558 European women from FinnGen and a previous UL meta-GWAS. In addition to the 50 known UL loci, we identify 22 loci that have not been associated with UL in prior studies. UL-associated loci harbour genes enriched for development, growth, and cellular senescence. Of particular interest are the smooth muscle cell differentiation and proliferation-regulating genes functioning on the myocardin-cyclin dependent kinase inhibitor 1A pathway. Our results further suggest that genetic predisposition to increased fat-free mass may be causally related to higher UL risk, underscoring the involvement of altered muscle tissue biology in UL pathophysiology. Overall, our findings add to the understanding of the genetic pathways underlying UL, which may aid in developing novel therapeutics.
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| 2. |
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| 3. |
- Paul, E. S., et al.
(författare)
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The highest spin discrete levels in Ce-131,Ce-132
- 2006
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Ingår i: Physica Scripta. - 0031-8949. ; T125, s. 115-118
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Tidskriftsartikel (refereegranskat)abstract
- The three superdeformed (SD) bands in Ce-132 and the two SD bands in Ce-131 have been extended to higher spin following experiments with the EUROBALL IV spectrometer. The two SD bands in 131Ce have been linked together. However, despite the relatively high population intensity of the bands ( up to 5% of the respective channel), it has not been possible to unambiguously link any of the five SD bands into the low-spin, normally deformed structures of Ce-131,Ce-132.
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| 4. |
- Simpson, J., et al.
(författare)
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Evolution of structure and shapes in Er 158 to ultrahigh spin
- 2023
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Ingår i: Physical Review C. - 2469-9985. ; 107:5
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Tidskriftsartikel (refereegranskat)abstract
- The level structure of Er158 has been studied using the Gammasphere spectrometer via the Cd114(Ca48,4n) reaction at 215 MeV with both thin (self-supporting) and thick (backed) targets. The level scheme has been considerably extended with more than 200 new transitions and six new rotational structures, including two strongly coupled high-K bands. Configuration assignments for the new structures are based on their observed alignments, B(M1)/B(E2) ratios of reduced transition probabilities, excitation energies, and comparisons with neighboring nuclei and theoretical calculations. With increasing angular momentum, this nucleus exhibits Coriolis-induced alignments of both neutrons and protons before it then undergoes a rotation-induced transition from near-prolate collective rotation to a noncollective oblate configuration. This transition occurs via the mechanism of band termination around spin 45ħ in three rotational structures. Two distinct lifetime branches, consistent with the crossing of a collective "fast"rotational structure by an energetically favored "slow"terminating sequence, are confirmed for the positive-parity states, and similar behavior is established in the negative-parity states. Weak-intensity, high-energy transitions are observed to feed into the terminating states. At the highest spins, three collective bands with high dynamic moments of inertia and large quadrupole moments were identified. These bands are interpreted as triaxial strongly deformed structures and mark a return to collectivity at ultrahigh spin.
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| 5. |
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| 6. |
- Choy, W. C. H., et al.
(författare)
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Determination of internal quantum efficiency of OLEDs with the consideration of the Purcell effect
- 2009
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Ingår i: 2009 International Display Manufacturing Conference, 3D Systems and Applications, and Asia Display, IDMC/3DSA/Asia Display 2009.
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Konferensbidrag (refereegranskat)abstract
- Organic light-emitting devices (OLEDs) with various device configurations have been the subjects of intensive research due to their applications in display and lighting [1-4]. Considering the microcavity effect, OLEDs can be roughly categorized into two types, i.e., weak microcavity OLEDs and strong microcavity OLEDs. Conventional bottom emitting OLEDs are weak microcavity devices while OLEDs with distributed Bragg reflectors or two metallic electrodes are considered as strong microcavity devices. Light emission properties, including the internal quantum efficiency (IQE), external quantum efficiency, exciton lifetime and angular dependence, are distinct in the two types of OLEDs due to the Purcell effect [5-8].
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| 7. |
- Chen, X. W., et al.
(författare)
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Efficient and rigorous modeling of light emission in planar multilayer organic light-emitting diodes
- 2007
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Ingår i: Journal of Display Technology. - : Institute of Electrical and Electronics Engineers (IEEE). - 1551-319X. ; 3:2, s. 110-117
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Tidskriftsartikel (refereegranskat)abstract
- In this paper, we propose a technique to enable efficient and rigorous modeling of light emission in planar organic light-emitting diodes (OLEDs) composed of an arbitrary number of layers with different permittivity (including metals of a complex permittivity). The effects of the change of exciton radiative decay rate are explicitly included in the simulation. The numerical implementation of the technique is comprehensively discussed through an illustrative example. By using the proposed method, a bottom emitting OLED with a thick glass substrate is rigorously analyzed. The calculated results show a good agreement with the experimental results. The proposed method is efficient and well suited for optimizing OLEDs with complicated device structures. As a demonstration, we optimize the two-unit tandem top-emitting OLEDs with three types of charge generating layer. The results and design guidelines are given and discussed in detail.
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| 8. |
- Chen, X. W., et al.
(författare)
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Highly efficient and tunable fluorescence of a nanofluorophore in silica/metal dual shells with plasmonic resonance
- 2008
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Ingår i: Journal of Applied Physics. - : AIP Publishing. - 0021-8979 .- 1089-7550. ; 103:2
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Tidskriftsartikel (refereegranskat)abstract
- A dual-shell structure consisting of a silica buffer shell and a metallic outer shell is studied and designed for highly efficient and tunable fluorescence. The enhanced Purcell effect due to the plasmonic resonance and the dependence of the resonance on the structural parameters are analyzed and discussed through a classical electromagnetic approach. With the present dual-shell structure a fivefold enhancement of the fluorescence efficiency can be achieved for a nanofluorophore comprised of multiple tetramethylrhodamine isothiocyanate dye molecules, as compared to the nanofluorophore within a single silica shell. Furthermore, the peak wavelength of the fluorescence spectrum can be tuned easily (due to the variation of the surface plasmon resonance) by over 50 nm when the refractive index of the ambient material varies from 1.3 to 1.6.
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| 9. |
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| 10. |
- Riley, M A, et al.
(författare)
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Beyond band termination in Er-157 and the search for wobbling excitations in strongly deformed Hf-174
- 2005
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Ingår i: Journal of Physics G: Nuclear and Particle Physics. - : IOP Publishing. - 0954-3899 .- 1361-6471. ; 31:10, s. 1735-1740
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Tidskriftsartikel (refereegranskat)abstract
- High-spin terminating bands in heavy nuclei were first identified in nuclei around Er-158(90). While examples of special terminating states have been identified in a number of erbium isotopes, almost nothing is known about the states lying beyond band termination. In the present work the high-spin structure of Er-157 has been studied using the Gammasphere spectrometer. The subject of triaxial superdeformation and 'wobbling' modes in Lu nuclei has rightly attracted a great deal of attention. Very recently, four strongly or superdeformed (SD) sequences have been observed in Hf-174 and ultimate cranker calculations predict, such structures may have significant triaxial deformation. We have performed two experiments in an attempt to verify the possible triaxial nature of these bands. A lifetime measurement was performed to confirm the large (and similar) deformation of the bands. In addition, a high-statistics, thin-target experiment was run to search for linking transitions between the SD bands and possible wobbling modes.
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