| 1. |
- Rauer, H., et al.
(författare)
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The PLATO 2.0 mission
- 2014
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Ingår i: Experimental astronomy. - : Springer Science and Business Media LLC. - 0922-6435 .- 1572-9508. ; 38:1-2, s. 249-330
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Tidskriftsartikel (refereegranskat)abstract
- PLATO 2.0 has recently been selected for ESA's M3 launch opportunity (2022/24). Providing accurate key planet parameters (radius, mass, density and age) in statistical numbers, it addresses fundamental questions such as: How do planetary systems form and evolve? Are there other systems with planets like ours, including potentially habitable planets? The PLATO 2.0 instrument consists of 34 small aperture telescopes (32 with 25 s readout cadence and 2 with 2.5 s cadence) providing a wide field-of-view (2232 deg(2)) and a large photometric magnitude range (4-16 mag). It focuses on bright (4-11 mag) stars in wide fields to detect and characterize planets down to Earth-size by photometric transits, whose masses can then be determined by ground-based radial-velocity follow-up measurements. Asteroseismology will be performed for these bright stars to obtain highly accurate stellar parameters, including masses and ages. The combination of bright targets and asteroseismology results in high accuracy for the bulk planet parameters: 2 %, 4-10 % and 10 % for planet radii, masses and ages, respectively. The planned baseline observing strategy includes two long pointings (2-3 years) to detect and bulk characterize planets reaching into the habitable zone (HZ) of solar-like stars and an additional step-and-stare phase to cover in total about 50 % of the sky. PLATO 2.0 will observe up to 1,000,000 stars and detect and characterize hundreds of small planets, and thousands of planets in the Neptune to gas giant regime out to the HZ. It will therefore provide the first large-scale catalogue of bulk characterized planets with accurate radii, masses, mean densities and ages. This catalogue will include terrestrial planets at intermediate orbital distances, where surface temperatures are moderate. Coverage of this parameter range with statistical numbers of bulk characterized planets is unique to PLATO 2.0. The PLATO 2.0 catalogue allows us to e. g.: - complete our knowledge of planet diversity for low-mass objects, - correlate the planet mean density-orbital distance distribution with predictions from planet formation theories,- constrain the influence of planet migration and scattering on the architecture of multiple systems, and - specify how planet and system parameters change with host star characteristics, such as type, metallicity and age. The catalogue will allow us to study planets and planetary systems at different evolutionary phases. It will further provide a census for small, low-mass planets. This will serve to identify objects which retained their primordial hydrogen atmosphere and in general the typical characteristics of planets in such a low-mass, low-density range. Planets detected by PLATO 2.0 will orbit bright stars and many of them will be targets for future atmosphere spectroscopy exploring their atmospheres. Furthermore, the mission has the potential to detect exomoons, planetary rings, binary and Trojan planets. The planetary science possible with PLATO 2.0 is complemented by its impact on stellar and galactic science via asteroseismology as well as light curves of all kinds of variable stars, together with observations of stellar clusters of different ages. This will allow us to improve stellar models and study stellar activity. A large number of well-known ages from red giant stars will probe the structure and evolution of our Galaxy. Asteroseismic ages of bright stars for different phases of stellar evolution allow calibrating stellar age-rotation relationships. Together with the results of ESA's Gaia mission, the results of PLATO 2.0 will provide a huge legacy to planetary, stellar and galactic science.
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| 2. |
- Su, Zhan, et al.
(författare)
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Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.
- 2012
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 44:10
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Tidskriftsartikel (refereegranskat)abstract
- Barrett's esophagus is an increasingly common disease that is strongly associated with reflux of stomach acid and usually a hiatus hernia, and it strongly predisposes to esophageal adenocarcinoma (EAC), a tumor with a very poor prognosis. We report the first genome-wide association study on Barrett's esophagus, comprising 1,852 UK cases and 5,172 UK controls in the discovery stage and 5,986 cases and 12,825 controls in the replication stage. Variants at two loci were associated with disease risk: chromosome 6p21, rs9257809 (Pcombined=4.09×10(-9); odds ratio (OR)=1.21, 95% confidence interval (CI)=1.13-1.28), within the major histocompatibility complex locus, and chromosome 16q24, rs9936833 (Pcombined=2.74×10(-10); OR=1.14, 95% CI=1.10-1.19), for which the closest protein-coding gene is FOXF1, which is implicated in esophageal development and structure. We found evidence that many common variants of small effect contribute to genetic susceptibility to Barrett's esophagus and that SNP alleles predisposing to obesity also increase risk for Barrett's esophagus.
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| 3. |
- Birney, Ewan, et al.
(författare)
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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
- 2007
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 447:7146, s. 799-816
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Tidskriftsartikel (refereegranskat)abstract
- We report the generation and analysis of functional data from multiple, diverse experiments performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE Project. These data have been further integrated and augmented by a number of evolutionary and computational analyses. Together, our results advance the collective knowledge about human genome function in several major areas. First, our studies provide convincing evidence that the genome is pervasively transcribed, such that the majority of its bases can be found in primary transcripts, including non-protein-coding transcripts, and those that extensively overlap one another. Second, systematic examination of transcriptional regulation has yielded new understanding about transcription start sites, including their relationship to specific regulatory sequences and features of chromatin accessibility and histone modification. Third, a more sophisticated view of chromatin structure has emerged, including its inter-relationship with DNA replication and transcriptional regulation. Finally, integration of these new sources of information, in particular with respect to mammalian evolution based on inter- and intra-species sequence comparisons, has yielded new mechanistic and evolutionary insights concerning the functional landscape of the human genome. Together, these studies are defining a path for pursuit of a more comprehensive characterization of human genome function.
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| 4. |
- Guiglion, G., et al.
(författare)
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4MOST Survey Strategy Plan
- 2019
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Ingår i: Messenger. - 0722-6691. ; 175, s. 17-21
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- The current status of and motivation for the 4MOST survey strategy, as developed by the Consortium science team, are presented here. Key elements of the strategy are described, such as sky coverage, number of visits and total exposure times in different parts of the sky, and how to deal with different observing conditions. The task of organising the strategy is not simple, with many different surveys that have vastly different target brightnesses and densities, sample completeness levels, and signal-to-noise requirements. We introduce here a number of concepts that we will use to ensure all surveys are optimised. Astronomers who are planning to submit a Participating Survey proposal are strongly encouraged to read this article and any relevant 4MOST Survey articles in this issue of The Messenger such that they can optimally complement and benefit from the planned surveys of the 4MOST Consortium.
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| 5. |
- Walcher, C.~J., et al.
(författare)
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4MOST Scientific Operations
- 2019
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Ingår i: Messenger. - 0722-6691. ; 175, s. 12-16
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- The 4MOST instrument is a multi-object spectrograph that will address Galactic and extragalactic science cases simultaneously by observing targets from a large number of different surveys within each science exposure. This parallel mode of operation and the survey nature of 4MOST require some distinct 4MOST- specific operational features within the overall operations model of ESO. The main feature is that the 4MOST Consortium will deliver, not only the instrument, but also contractual services to the user community, which is why 4MOST is also described as a facility. This white paper concentrates on information particularly useful to answering the forthcoming Call for Letters of Intent.
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| 6. |
- Angelou, George C., et al.
(författare)
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Thermohaline mixing and the variation of [C/Fe] with magnitude in M3
- 2010
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Ingår i: 11th Symposium on Nuclei in the Cosmos, NIC 2010; Heidelberg; Germany; 19 July 2010 through 23 July 2010.
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Konferensbidrag (refereegranskat)abstract
- We use observations of M3 to constrain thermohaline mixing. This is done by matching [C/Fe] and [N/Fe] along the RGB of M3. We find our models can explain observations if it is assumed there is a spread of ∼ 0.3 - 0.4 dex in [C/Fe] in the stars in M3 from their birth. We reproduce the full spread in [C/Fe] at the tip of the RGB. Thermohaline mixing can produce a significant change in [N/Fe] as a function of absolute magnitude on the RGB for initially CN-weak stars, but not for initially CN-strong stars, which have so much nitrogen to begin with that any deep mixing does not significantly affect the surface nitrogen composition.
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| 7. |
- Askar, Abbas, et al.
(författare)
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Formation of supermassive black holes in galactic nuclei – I. Delivering seed intermediate-mass black holes in massive stellar clusters
- 2021
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Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 502:2, s. 2682-2700
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Tidskriftsartikel (refereegranskat)abstract
- Supermassive black holes (SMBHs) are found in most galactic nuclei. A significant fraction of these nuclei also contains a nuclear stellar cluster (NSC) surrounding the SMBH. In this paper, we consider the idea that the NSC forms first, from the merger of several stellar clusters that may contain intermediate-mass black holes (IMBHs). These IMBHs can subsequently grow in the NSC and form an SMBH. We carry out N-body simulations of the simultaneous merger of three stellar clusters to form an NSC, and investigate the outcome of simulated runs containing zero, one, two, and three IMBHs. We find that IMBHs can efficiently sink to the centre of the merged cluster. If multiple merging clusters contain an IMBH, we find that an IMBH binary is likely to form and subsequently merge by gravitational wave emission. We show that these mergers are catalyzed by dynamical interactions with surrounding stars, which systematically harden the binary and increase its orbital eccentricity. The seed SMBH will be ejected from the NSC by the recoil kick produced when two IMBHs merge, if their mass ratio q ≳ 0.15. If the seed is ejected then no SMBH will form in the NSC. This is a natural pathway to explain those galactic nuclei that contain an NSC but apparently lack an SMBH, such as M33. However, if an IMBH is retained then it can seed the growth of an SMBH through gas accretion and tidal disruption of stars.
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| 8. |
- Bobrick, Alexey, et al.
(författare)
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Mass transfer in white dwarf-neutron star binaries
- 2017
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Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 467:3, s. 3556-3575
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Tidskriftsartikel (refereegranskat)abstract
- We perform hydrodynamic simulations of mass transfer in binaries that contain a white dwarf and a neutron star (WD-NS binaries), and measure the specific angular momentum of material lost from the binary in disc winds. By incorporating our results within a long-term evolution model, we measure the long-term stability of mass transfer in these binaries. We find that only binaries containing helium white dwarfs (WDs) with masses less than a critical mass of M-WD, (crit) = 0.2 M-circle dot undergo stable mass transfer and evolve into ultracompact X-ray binaries. Systems with higher mass WDs experience unstable mass transfer, which leads to tidal disruption of the WD. Our low critical mass compared to the standard jet-only model of mass-loss arises from the efficient removal of angular momentum in the mechanical disc winds, which develop at highly super-Eddington mass-transfer rates. We find that the eccentricities expected for WD-NS binaries when they come into contact do not affect the loss of angular momentum, and can only affect the long-term evolution if they change on shorter time-scales than the mass-transfer rate. Our results are broadly consistent with the observed numbers of both ultracompact X-ray binaries and radio pulsars with WD companions. The observed calcium-rich gap transients are consistent with the merger rate of unstable systems with higher mass WDs.
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| 9. |
- Christleib, Norbert, et al.
(författare)
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4MOST Consortium Survey 2: The Milky Way Halo High-Resolution Survey
- 2019
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Ingår i: Messenger. - 0722-6691. ; 175, s. 26-29
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- We will study the formation history of the Milky Way, and the earliest phases of its chemical enrichment, with a sample of more than 1.5 million stars at high galactic latitude. Elemental abundances of up to 20 elements with a precision of better than 0.2 dex will be derived for these stars. The sample will include members of kinematically coherent substructures, which we will associate with their possible birthplaces by means of their abundance signatures and kinematics, allowing us to test models of galaxy formation. Our target catalogue is also expected to contain 30 000 stars at a metallicity of less than one hundredth that of the Sun. This sample will therefore be almost a factor of 100 larger than currently existing samples of metal-poor stars for which precise elemental abundances are available (determined from high-resolution spectroscopy), enabling us to study the early chemical evolution of the Milky Way in unprecedented detail.
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| 10. |
- Church, Ross P., et al.
(författare)
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Detailed models of the binary pulsars J1141-6545 and B2303+46
- 2006
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Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 1365-2966 .- 0035-8711. ; 372:2, s. 715-727
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Tidskriftsartikel (refereegranskat)abstract
- We have modelled the formation of the eccentric double-degenerate binaries J1141-6545 and B2303+46 using the Henyey-type full stellar evolution code STARS and the population synthesis code BSE. We find that the outcome depends strongly on the common envelope (CE) evolution efficiency parameter alpha(CE) and show that both systems can be modelled with a single value of alpha(CE). The final orbit of the system depends critically on the order of Roche lobe filling events. The phase space of progenitors and the different evolutionary pathways followed by binary stars that form eccentric double-degenerate binaries in the two codes are compared. We show that the pathways are similar between the codes and that the distribution of progenitors in mass and separation phase space is qualitatively the same, thus validating the use of BSE-like population synthesis for simulations of this type. The phase space of initial parameters is very different to that obtained using ad hoc arguments about the evolution, which shows that such arguments are insufficient to model evolutionary pathways of this complexity. There are some differences associated with the prescription adopted for CE evolution but these are not qualitatively significant. We investigate the dependence of the formation mechanism on wind mass loss and the CE efficiency parameter alpha(CE), showing that it depends strongly on the latter but rather less on the former.
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