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Sökning: WFRF:(Clarhed Ulrika)

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1.
  • Clarhed, Ulrika, et al. (författare)
  • BMI as a risk factor for the development of chronic rhinosinusitis: a prospective population-based study
  • 2022
  • Ingår i: European Archives of Oto-Rhino-Laryngology. - : Springer Science and Business Media LLC. - 0937-4477 .- 1434-4726. ; 279, s. 4953-4959
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose Obesity is a growing, global health problem and previous cross-sectional studies have demonstrated an association between obesity and chronic rhinosinusitis (CRS). There is, however, a lack of prospective studies regarding the impact of obesity on developing (new-onset) CRS. Methods Questionnaire-based data (n = 5769) relating to new-onset CRS and Body Mass Index (BMI) were collected in 2013 and 2018 from the Telemark population study in Telemark, Norway. Odds ratios for the risk of new-onset CRS in 2018 in relation to BMI in 2013 were calculated, adjusted for smoking habits, asthma, gender and age. Results When comparing the group with normal weight (18.5 <= BMI < 25) with the obese group (BMI >= 30), the odds of new-onset CRS was 53% higher [OR 1.53 (1.11, 2.10)] in the obese group. Conclusion CRS is a multifactorial disease with different phenotypes and it is important to consider obesity when assessing patients with CRS in a clinical setting.
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2.
  • Clarhed, Ulrika, et al. (författare)
  • Chronic Rhinosinusitis Related to Occupational Exposure- the Telemark Population Study.
  • 2018
  • Ingår i: Journal of occupational and environmental medicine. - 1536-5948. ; 60:7, s. 656-660
  • Tidskriftsartikel (refereegranskat)abstract
    • To investigate the association between occupational exposure and chronic rhinosinusitis.A random population from the region of Telemark, aged 16-50, answered a respiratory questionnaire including questions on chronic rhinosinusitis and exposure in the occupational environment.A total of 16,099/48,142 subjects responded. The prevalence of chronic rhinosinusitis was 9%. Exposure associated with chronic rhinosinusitis comprised paper dust (OR 1.3, 95% CI 1.1, 1.5), cleaning agents (OR 1.2, CI 1.0, 1.3), metal dust (OR 1.3, CI 1.1, 1.6), animals (OR 1.2, CI 1.0, 1.5), moisture/mould/mildew (OR 1.3, CI 1.1, 1.5) and physically strenuous work (OR 1.4, CI 1.2, 1.7).Occupational exposure to paper dust, cleaning agents, metal dust, animals, moisture/mould/mildew and physically strenuous work was independently related to having chronic rhinosinusitis. An occupational history should be reviewed when assessing patients with chronic rhinosinusitis.
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3.
  • Clarhed, Ulrika, et al. (författare)
  • Occupational exposure and the risk of new-onset chronic rhinosinusitis - a prospective study 2013-2018.
  • 2020
  • Ingår i: Rhinology. - 0300-0729. ; 58:6, s. 597-604
  • Tidskriftsartikel (refereegranskat)abstract
    • The aetiology behind chronic rhinosinusitis (CRS) is still poorly understood. The aim of this study was to investigate the association between the onset of CRS and several common occupational exposures over time.An adult random population from Telemark, Norway, comprising 7,952 subjects, who answered a comprehensive respiratory questionnaire including questions on CRS and occupational exposure first in 2013 and again in 2018.New-onset CRS during the five-year follow-up was independently associated with occupational exposure to hair-care products, cleaning agents among women, super glue, strong acids, cooking fumes and wood dust.In this random population cohort from Norway, exposure to several common occupational agents, such as hair-care products, super glue and wood dust, was associated with the onset of CRS. It is important that physicians who see patients with CRS inquire about workplace exposure.
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