| 1. |
- Conter, Marco, et al.
(författare)
-
PROCEEDR - Optimizing Resources for more Sustainable Noise and Safety Barriers on European Roads
- 2023
-
Ingår i: Transportation Research Procedia. - 2352-1465 .- 2352-1457. ; 72, s. 596-603
-
Konferensbidrag (refereegranskat)abstract
- PROCEEDR aims to create tools to enable National Road Administrations to identify innovative and sustainable solutions to facilitate the transition from linear to circular economy in the field of roadside infrastructure. At the same time, high functional demand and technical performance requirements still need to be met. Therefore, the scope of PROCEEDR is to gather an overview of innovative and sustainable solutions with focus on noise and safety barriers, as well as to provide tools for selecting the most suitable and cost-effective solutions. The paper gives a general overview of the project goals and the methodology to be used, showing also the first activities performed. More detailed results will be presented at the conference in November 2022, while other project results will be presented in the frame of upcoming conferences.
|
|
| 2. |
- Conter, Marco, et al.
(författare)
-
ROSANNE project : New procedure for noise characterization of road surfaces in Europe
- 2016
-
Ingår i: Proceedings of the INTER-NOISE 2016 - 45th International Congress and Exposition on Noise Control Engineering. ; , s. 4997-5005
-
Konferensbidrag (refereegranskat)abstract
- ROSANNE is a collaborative project in the 7th EU Framework Program which aims at harmonizing measurement methods for skid resistance, noise emission and rolling resistance of road pavements as a preparation for standardization. The project started in November 2013 and is developing and improving standards in the field of working group CEN/TC 227/WG 5.Regarding the influence of the pavement on the road traffic noise emission, the main objective is to combine the existing measurement methods of SPB (ISO 11819-1) and CPX (ISO/DIS 11819-2) into a stable and reliable harmonized pavement noise emission characterization method. A respective procedure is being developed within the project and its potential use for noise calculation methods like the one proposed by the CNOSSOS-EU project is investigated. The first two years of research focused on analyzing and comparing existing noise measurement methods to specify the noise properties of road surfaces as well as investigating the temperature influence of possible correction measures; respective results will be presented in a separate paper on this issue within this conference. Activities related to the compatibility with the CNOSSOS-EU calculation method and to the experimental validation are still ongoing. The present paper shows the current draft of the procedure developed.
|
|
| 3. |
- Haider, Manfred, et al.
(författare)
-
Status of the EU-project ROSANNE
- 2016
-
Ingår i: Transportation Research Procedia. - : Elsevier BV. - 2352-1465. ; , s. 2946-2955
-
Konferensbidrag (refereegranskat)abstract
- ROSANNE is a collaborative project in the Seventh EU Framework Programme which aims at developing/harmonising measurement methods for skid resistance, noise emission and rolling resistance of road pavements as a preparation for standardization. To achieve this, the project is following the recommendations of key predecessor projects like TYROSAFE, HERMES, SILVIA, SILENCE and MIRIAM as well as considering the ongoing work in CEN and ISO groups.Work package 1 deals with skid resistance and aims at the harmonization of skid resistance measurement following the TYROSAFE Roadmap, by deriving conversion factors for friction indices based on similar groups of devices, namely longitudinal and sideways skid resistance measurement devices. During the first project year a first round robin test was carried out in Nantes, ten different devices participated to the test. The results of this test are collected in report D1.2 "Analysis of data from the first round of tests and initial development of the common scale".Work package 2 is dealing with the pavement influence on road traffic noise emission: the main objective of this work package is to combine the existing measurement methods of SPB (ISO 11819-1) and CPX (ISO/DIS 11819-2) into a stable and reliable harmonised pavement noise emission characterisation method. The project is validating procedure incorporating correction mechanisms for temperature influence and investigating its potential use for noise calculation methods like the one proposed by the CNOSSOS-EU project.Work package 3 is dealing with rolling resistance, where the ROSANNE project is mainly building on the results obtained in the MIRIAM project and is considering standardized trailer measurements of rolling resistance coefficients of road surfaces. After a first report D3.1 "State of the art on rolling resistance measurement devices including draft standard outline" the following main report was produced "Parameters influencing rolling resistance and possible correction procedures".In the frame of work package 4 the project is also exploring the potential for developments in the measurement of surface texture in order to find out parameters that better reflect the physical process of tyre/road interaction and that may improve the understanding of how the texture influences noise emission, skid resistance and rolling resistance. In addition to that this work package is also investigating the performance of reference tyres and pavements which are necessary for the measurement of all three road surface properties. The present paper summarizes the project status after the first 18 project months.
|
|
| 4. |
- Sandberg, Ulf, et al.
(författare)
-
Improving the CPX method by specifying reference tyres and including corrections for rubber hardness and temperature
- 2016
-
Ingår i: Proceedings of the INTER-NOISE 2016 - 45th International Congress and Exposition on Noise Control Engineering. ; , s. 4913-4923
-
Konferensbidrag (refereegranskat)abstract
- Recently completed work in the EU project ROSANNE and in working group ISO/TC43/SC1/WG33 has allowed substantial improvements to measurements made by the Close-Proximity (CPX) method, intended for measurement of noise properties of road surfaces. The paper summarizes the experimental work and describes the conclusions and implementation in ISO/FDIS 11819-2 (the CPX method) and in the supporting ISO (draft) Technical Specifications 11819-3 about Reference Tyres and 13471-1 about Temperature Corrections.In the Reference Tyre specification, two reference tyres are defined, of which one is the 16'' SRTT specified in ASTM 2493-14 and the other is a commercial light truck tyre. Both tyres have been tested with respect to correlations with SPB (pass-by) measurements and found to represent car and truck tyres, respectively, in this particular application. To account for reasonable ageing and minor production differences, a correction for rubber hardness is specified, in order to normalize measurement results to tyres having reference hardness. The Temperature Correction specification includes temperature coefficients that are used for normalizing noise levels to an air reference temperature of 20 degrees C. The coefficients relate to driving speed by a simple equation which is different for three categories of road surfaces, which are specified in the document.
|
|
| 5. |
- Sandberg, Ulf, 1946-, et al.
(författare)
-
Rolling resistance : basic information and state-of-the-art on measurement methods. Final version
- 2011
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- MIRIAM has established a sub-project (SP), designated SP 1, to deal with measurement methods for rolling resistance and related issues. This subject forms the most fundamental basis for the MIRIAM ambition to consider rolling resistance in pavement management or other types of infrastructure systems. Without robust measurement methods and equipment that can use them there will be no reliable data as input to such systems and the end result will be most uncertain, if useful at all.In order to develop and study measurement methods, there must be a basic understanding of the influencing parameters as well as what energy losses that should be included in the concept of rolling resistance. These issues are, therefore, important parts of the work in SP 1.This report is intended to provide basic knowledge about the part of the tyre and road interaction which relates to rolling resistance; for example, the mechanisms that create rolling resistance, and the influence on rolling resistance of various tyre and road parameters. The intention is also to suggest a definition of rolling resistance for the purposes of this project, as well as to provide some detailed state-of-the-art knowledge about the measurement methods and equipment that are useful for collecting rolling resistance data.
|
|
| 6. |
- Zhukova, Nataliya, et al.
(författare)
-
WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma
- 2014
-
Ingår i: Acta neuropathologica communications. - : Springer Science and Business Media LLC. - 2051-5960. ; 2
-
Tidskriftsartikel (refereegranskat)abstract
- TP53 mutations confer subgroup specific poor survival for children with medulloblastoma. We hypothesized that WNT activation which is associated with improved survival for such children abrogates TP53 related radioresistance and can be used to sensitize TP53 mutant tumors for radiation. We examined the subgroup-specific role of TP53 mutations in a cohort of 314 patients treated with radiation. TP53 wild-type or mutant human medulloblastoma cell-lines and normal neural stem cells were used to test radioresistance of TP53 mutations and the radiosensitizing effect of WNT activation on tumors and the developing brain. Children with WNT/TP53 mutant medulloblastoma had higher 5-year survival than those with SHH/TP53 mutant tumours (100% and 36.6%±8.7%, respectively (p<0.001)). Introduction of TP53 mutation into medulloblastoma cells induced radioresistance (survival fractions at 2Gy (SF2) of 89%±2% vs. 57.4%±1.8% (p<0.01)). In contrast, beta-catenin mutation sensitized TP53 mutant cells to radiation (p<0.05). Lithium, an activator of the WNT pathway, sensitized TP53 mutant medulloblastoma to radiation (SF2 of 43.5%±1.5% in lithium treated cells vs. 56.6±3% (p<0.01)) accompanied by increased number of gammaH2AX foci. Normal neural stem cells were protected from lithium induced radiation damage (SF2 of 33%±8% for lithium treated cells vs. 27%±3% for untreated controls (p=0.05). Poor survival of patients with TP53 mutant medulloblastoma may be related to radiation resistance. Since constitutive activation of the WNT pathway by lithium sensitizes TP53 mutant medulloblastoma cells and protect normal neural stem cells from radiation, this oral drug may represent an attractive novel therapy for high-risk medulloblastomas.
|
|
