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- Carraminana, Albert, et al.
(författare)
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Rationale and Study Design for an Individualized Perioperative Open Lung Ventilatory Strategy in Patients on One-Lung Ventilation (iPROVE-OLV)
- 2019
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Ingår i: Journal of Cardiothoracic and Vascular Anesthesia. - : W B SAUNDERS CO-ELSEVIER INC. - 1053-0770 .- 1532-8422. ; 33:9, s. 2492-2502
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of this clinical trial is to examine whether it is possible to reduce postoperative complications using an individualized perioperative ventilatory strategy versus using a standard lung-protective ventilation strategy in patients scheduled for thoracic surgery requiring one-lung ventilation. Design: International, multicenter, prospective, randomized controlled clinical trial. Setting: A network of university hospitals. Participants: The study comprises 1,380 patients scheduled for thoracic surgery. Interventions: The individualized group will receive intraoperative recruitment maneuvers followed by individualized positive end-expiratory pressure (open lung approach) during the intraoperative period plus postoperative ventilatory support with high-flow nasal cannula, whereas the control group will be managed with conventional lung-protective ventilation. Measurements and Main Results: Individual and total number of postoperative complications, including atelectasis, pneumothorax, pleural effusion, pneumonia, acute lung injury; unplanned readmission and reintubation; length of stay and death in the critical care unit and in the hospital will be analyzed for both groups. The authors hypothesize that the intraoperative application of an open lung approach followed by an individual indication of high-flow nasal cannula in the postoperative period will reduce pulmonary complications and length of hospital stay in high-risk surgical patients. (C) 2019 Published by Elsevier Inc.
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| 2. |
- Hudson, Lawrence N, et al.
(författare)
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The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project
- 2017
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Ingår i: Ecology and Evolution. - : John Wiley & Sons. - 2045-7758. ; 7:1, s. 145-188
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Tidskriftsartikel (refereegranskat)abstract
- The PREDICTS project-Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)-has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to develop global and regional statistical models of how local biodiversity responds to these measures. We describe and make freely available this 2016 release of the database, containing more than 3.2 million records sampled at over 26,000 locations and representing over 47,000 species. We outline how the database can help in answering a range of questions in ecology and conservation biology. To our knowledge, this is the largest and most geographically and taxonomically representative database of spatial comparisons of biodiversity that has been collated to date; it will be useful to researchers and international efforts wishing to model and understand the global status of biodiversity.
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| 3. |
- McCabe, Patrick, et al.
(författare)
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Reference Points for the Design and Delivery of Degree Programs in Business
- 2009
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- The Tuning Subject Area Group (SAG) for business and managementeducation met on some twelve occasions. The first meeting coincided with the launch of the EU–sponsored Tuning project in Brussels in May 2001; the last took place in June 2008 in conjunction with the closing session of the fourth phase of Tuning (Tuning IV). Over the eight years, we shared our experiences of business programmes in our own institutions, our own countries and – in many instances – elsewhere within and beyond Europe. We pooled our ideas concerning the implementation of the various ‘action lines’ of the Bologna Declaration, the aim of which is the creation of a more coherent European Higher Education Area (EHEA) by 2010.Competence–based learner–centred education is at the heart of the Tuning approach. Degree profiles and learning outcomes for the bachelor, master and doctoral cycles are identifi ed as a starting point for debate at a more local level. Likewise, teaching, learning and assessment are addressed, as well as the crucial issue of quality enhancement. The booklet concludes with a look at the third cycle.The work of Tuning, involving contributions by individuals from a wide range of disciplines in 135 institutions across 27 countries, is seen as fully compatible with and complementary to the aims of the Bologna process, as expressed in 1999 and at subsequent follow–up meetings. Indeed it might be claimed that its work and outputs represent a valuable pan–European movement that greatly facilitates and accelerates the achievement of the Bologna objectives. As noted on the opening page of this brochure, there is no intention to standardize or prescribe; on the contrary, respect for and the preservation of Europe’s rich tapestry of educational activities remain as the fundamental principles of the Tuning project.It is hoped that this booklet, when read in conjunction with the impressive array of publications produced by Tuning over the past several years, will stimulate discussion that will lead to the (re–)design and delivery of business programmes that simultaneously provide greater rewards for learners, teachers, institutions, employers and society.The Tuning Subject Area Group for Business and Management Education.
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