| 1. |
- Carraminana, Albert, et al.
(författare)
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Rationale and Study Design for an Individualized Perioperative Open Lung Ventilatory Strategy in Patients on One-Lung Ventilation (iPROVE-OLV)
- 2019
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Ingår i: Journal of Cardiothoracic and Vascular Anesthesia. - : W B SAUNDERS CO-ELSEVIER INC. - 1053-0770 .- 1532-8422. ; 33:9, s. 2492-2502
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of this clinical trial is to examine whether it is possible to reduce postoperative complications using an individualized perioperative ventilatory strategy versus using a standard lung-protective ventilation strategy in patients scheduled for thoracic surgery requiring one-lung ventilation. Design: International, multicenter, prospective, randomized controlled clinical trial. Setting: A network of university hospitals. Participants: The study comprises 1,380 patients scheduled for thoracic surgery. Interventions: The individualized group will receive intraoperative recruitment maneuvers followed by individualized positive end-expiratory pressure (open lung approach) during the intraoperative period plus postoperative ventilatory support with high-flow nasal cannula, whereas the control group will be managed with conventional lung-protective ventilation. Measurements and Main Results: Individual and total number of postoperative complications, including atelectasis, pneumothorax, pleural effusion, pneumonia, acute lung injury; unplanned readmission and reintubation; length of stay and death in the critical care unit and in the hospital will be analyzed for both groups. The authors hypothesize that the intraoperative application of an open lung approach followed by an individual indication of high-flow nasal cannula in the postoperative period will reduce pulmonary complications and length of hospital stay in high-risk surgical patients. (C) 2019 Published by Elsevier Inc.
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| 2. |
- Fomalont, E. B., et al.
(författare)
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THE 2014 ALMA LONG BASELINE CAMPAIGN: AN OVERVIEW
- 2015
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Ingår i: Astrophysical Journal Letters. - : American Astronomical Society. - 2041-8213 .- 2041-8205. ; 808:1
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Tidskriftsartikel (refereegranskat)abstract
- A major goal of the Atacama Large Millimeter/submillimeter Array (ALMA) is to make accurate images with resolutions of tens of milliarcseconds, which at submillimeter (submm) wavelengths requires baselines up to similar to 15 km. To develop and test this capability, a Long Baseline Campaign (LBC) was carried out from 2014 September to late November, culminating in end-to-end observations, calibrations, and imaging of selected Science Verification (SV) targets. This paper presents an overview of the campaign and its main results, including an investigation of the short-term coherence properties and systematic phase errors over the long baselines at the ALMA site, a summary of the SV targets and observations, and recommendations for science observing strategies at long baselines. Deep ALMA images of the quasar 3C 138 at 97 and 241 GHz are also compared to VLA 43 GHz results, demonstrating an agreement at a level of a few percent. As a result of the extensive program of LBC testing, the highly successful SV imaging at long baselines achieved angular resolutions as fine as 19 mas at similar to 350 GHz. Observing with ALMA on baselines of up to 15 km is now possible, and opens up new parameter space for submm astronomy.
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| 3. |
- Nunes, Sílvia C., et al.
(författare)
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Corrigendum: Leaf surfaces and neolithization - the case of Arundo donax L(Front. Plant Sci., (2022), 13, (999252), 10.3389/fpls.2022.999252)
- 2024
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Ingår i: Frontiers in Plant Science. - : Frontiers Media SA. - 1664-462X. ; 15
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- In the published article, there was an error in the Acknowledgments statement regarding CQ-VR. The section previously stated: “This research was funded by National Funds from Foundation for Science and Technology (FCT) and FEDER through POCI-COMPETE 2020-Operational Programme Competitiveness and Internationalization in Axis I-Strengthening research, technological development and innovation (UID/QUI/00616/2013 and UID/QUI/00616/2019 to CQ-VR, UIDB/04033/2020 to CITAB, UIDB/00195/2020 to FibEnTech and UID/QUI/50006/2020 to LAQV/Requimte) and by the project PORPLANTSURF - Superhydrophobic films inspired by the surface of plant leaves and petals from Northern Portugal (POCI-01−0145-FEDER-029785), financed by the European Regional Development Fund (ERDF) through COMPETE 2020-Operational Program for Competitiveness and Internationalization (POCI) and FCT. SN acknowledges FCT for Assistant Research contract (2020-00805.CEEIND) in scope of Scientific Employment Stimulus. The authors acknowledge to Patrick Joel Pais for the preparation of the fresh leaf for SEM analysis. PN acknowledges CQ-VR/FCT for a PhD grant (UI/BD/151084/2021). AR and SA acknowledge partial support from the Swedish Energy Agency (grant no. 49227-1). MF acknowledges FCT-UTAD for the contract in the scope of Decreto-Lei 57/2016−Lei 57/2017.” The corrected statement appears below: “This research was funded by National Funds from Foundation for Science and Technology (FCT) and FEDER through POCI-COMPETE 2020-Operational Programme Competitiveness and Internationalization in Axis I-Strengthening research, technological development and innovation (UIDB/00616/2020 (https://doi.org/10.54499/UIDB/00616/2020) and UIDP/00616/2020 (https://doi.org/10.54499/UIDP/00616/2020) to CQ-VR, UIDB/04033/2020 to CITAB, UIDB/00195/2020 (https://doi.org/10.54499/UIDB/00195/2020) to FibEnTech and UID/QUI/50006/2020 to LAQV/Requimte) and by the project PORPLANTSURF - Superhydrophobic films inspired by the surface of plant leaves and petals from Northern Portugal (POCI-01−0145-FEDER-029785), financed by the European Regional Development Fund (ERDF) through COMPETE 2020-Operational Program for Competitiveness and Internationalization (POCI) and FCT. SN acknowledges FCT for the Assistant Research contract (2020-00805.CEEIND, https://doi.org/10.54499/2020.00805.CEECIND/CP1625/CT0001) in the scope of the Scientific Employment Stimulus. The authors acknowledge Patrick Joel Pais for the preparation of the fresh leaf for SEM analysis. PN acknowledges CQ-VR/FCT for a PhD grant (UI/BD/151084/2021). AR and SA acknowledge partial support from the Swedish Energy Agency (grant no. 49227-1). MF acknowledges FCT-UTAD for the contract in the scope of Decreto-Lei 57/2016−Lei 57/2017”. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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| 4. |
- Nunes, Silvia C., et al.
(författare)
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Leaf surfaces and neolithization-the case of Arundo donax L
- 2022
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Ingår i: Frontiers in Plant Science. - : Frontiers Media SA. - 1664-462X. ; 13
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Tidskriftsartikel (refereegranskat)abstract
- Arundo donax L. (Arundinoideae subfamily, Poaceae family) is a sub-tropical and temperate climate reed that grows in arid and semi-arid environmental conditions, from eastern China to the Mediterranean basin, suggesting potential adaptations at the epicuticular level. A thorough physical-chemical examination of the adaxial and abaxial surfaces of A. donax leaf was performed herein in an attempt to track such chemophenetic adaptations. This sort of approach is of the utmost importance for the current debate about the hypothetical invasiveness of this species in the Mediterranean basin versus its natural colonization along the Plio-Pleistocene period. We concluded that the leaf surfaces contain, apart from stomata, prickles, and long, thin trichomes, and silicon-rich tetralobate phytolits. Chemically, the dominating elements in the leaf ashes are oxygen and potassium; minor amounts of calcium, silicon, magnesium, phosphorous, sulphur, and chlorine were also detected. In both surfaces the epicuticular waxes (whose density is higher in the adaxial surface than in the abaxial surface) form randomly orientated platelets, with irregular shape and variable size, and aggregated rodlets with variable diameter around the stomata. In the case of green mature leaves, the dominating organic compounds of the epicuticular waxes of both surfaces are triterpenoids. Both surfaces feature identical hydrophobic behaviour, and exhibit the same total transmittance, total reflectance, and absorption of incident light. The above findings suggest easy growth of the plant, remarkable epidermic robustness of the leaf, and control of water loss. These chemophenetic characteristics and human influence support a neolithization process of this species along the Mediterranean basin.
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| 5. |
- Organista, Elia, et al.
(författare)
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Taphonomic analysis of the level 3b fauna at BK, Olduvai Gorge
- 2019
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Ingår i: Quaternary International. - : Elsevier BV. - 1040-6182 .- 1873-4553. ; 526, s. 116-128
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Tidskriftsartikel (refereegranskat)abstract
- The association of stone tools and modified bones at archaeological African Plio-Pleistocene sites is essential to understanding the socio-economics of early hominin behavior. Previous research at BK suggests the site was repeatedly visited by hominins for short time periods. During these occupations, the hominins had a primary role in the exploitation of small, medium, and large size carcasses. The present study analyzes the faunal material recovered from level 3b at BK (BK3b). The results indicate that BK3b operated as a place consciously selected by hominins to carry out specific activities, which resulted in a large accumulation of lithic materials and bone remains. The high frequency of cut-marked specimens, even more than is documented at FLK Zinj, supports the idea that hominins at BK3b butchered and demarrowed the bones from animals of all sizes.
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| 6. |
- Pereira, Rui F. P., et al.
(författare)
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Vicariance Between Cercis siliquastrum L. and Ceratonia siliqua L. Unveiled by the Physical-Chemical Properties of the Leaves' Epicuticular Waxes
- 2022
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Ingår i: Frontiers in Plant Science. - : Frontiers Media SA. - 1664-462X. ; 13
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Tidskriftsartikel (refereegranskat)abstract
- Classically, vicariant phenomena have been essentially identified on the basis of biogeographical and ecological data. Here, we report unequivocal evidences that demonstrate that a physical-chemical characterization of the epicuticular waxes of the surface of plant leaves represents a very powerful strategy to get rich insight into vicariant events. We found vicariant similarity between Cercis siliquastrum L. (family Fabaceae, subfamily Cercidoideae) and Ceratonia siliqua L. (family Fabaceae, subfamily Caesalpinoideae). Both taxa converge in the Mediterranean basin (C. siliquastrum on the north and C. siliqua across the south), in similar habitats (sclerophyll communities of maquis) and climatic profiles. These species are the current representation of their subfamilies in the Mediterranean basin, where they overlap. Because of this biogeographic and ecological similarity, the environmental pattern of both taxa was found to be very significant. The physical-chemical analysis performed on the epicuticular waxes of C. siliquastrum and C. siliqua leaves provided relevant data that confirm the functional proximity between them. A striking resemblance was found in the epicuticular waxes of the abaxial surfaces of C. siliquastrum and C. siliqua leaves in terms of the dominant chemical compounds (1-triacontanol (C30) and 1-octacosanol (C28), respectively), morphology (intricate network of randomly organized nanometer-thick and micrometer-long plates), wettability (superhydrophobic character, with water contact angle values of 167.5 +/- 0.5 degrees and 162 +/- 3 degrees, respectively), and optical properties (in both species the light reflectance/absorptance of the abaxial surface is significantly higher/lower than that of the adaxial surface, but the overall trend in reflectance is qualitatively similar). These results enable us to include for the first time C. siliqua in the vicariant process exhibited by C. canadensis L., C. griffithii L., and C. siliquastrum.
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| 7. |
- Waldman, Meryl, et al.
(författare)
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COVID-19 in Patients with Glomerular Disease: Follow-Up Results from the IRoc-GN International Registry
- 2022
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Ingår i: KIDNEY360. - : AMER SOC NEPHROLOGY. - 2641-7650. ; 3:2, s. 293-306
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Tidskriftsartikel (refereegranskat)abstract
- Background The acute and long-term effects of severe acute respiratory syndrome coronavirus 2 infection in individuals with GN are still unclear. To address this relevant issue, we created the International Registry of COVID-19 infection in GN.Methods We collected serial information on kidney-related and-unrelated outcomes from 125 GN patients (63 hospitalized and 62 outpatients) and 83 non-GN hospitalized patients with coronavirus disease 2019 (COVID-19) and a median follow-up period of 6.4 (interquartile range 2.3-9.6) months after diagnosis. We used logistic regression for the analyses of clinical outcomes and linear mixed models for the longitudinal analyses of eGFR. All multiple regression models were adjusted for age, sex, ethnicity, and renin-angiotensin-aldosterone system inhibitor use.Results After adjustment for pre-COVID-19 eGFR and other confounders, mortality and AKI did not differ between GN patients and controls (adjusted odds ratio for AKI=1.28; 95% confidence interval [CI], 0.46 to 3.60; P=0.64). The main predictor of AKI was pre-COVID-19 eGFR (adjusted odds ratio per 1 SD unit decrease in eGFR=3.04; 95% CI, 1.76 to 5.28; P,0.001). GN patients developing AKI were less likely to recover pre-COVID19 eGFR compared with controls (adjusted 6-month post-COVID-19 eGFR=0.41; 95% CI, 0.25 to 0.56; times preCOVID-19 eGFR). Shorter duration of GN diagnosis, higher pre-COVID-19 proteinuria, and diagnosis of focal segmental glomerulosclerosis or minimal change disease were associated with a lower post-COVID-19 eGFR.Conclusions Pre-COVID-19 eGFR is the main risk factor for AKI regardless of GN diagnosis. However, GN patients are at higher risk of impaired eGFR recovery after COVID-19-associated AKI. These patients (especially those with high baseline proteinuria or a diagnosis of focal segmental glomerulosclerosis or minimal change disease) should be closely monitored not only during the acute phases of COVID-19 but also after its resolution.
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