| 1. |
- Glasbey, JC, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 2. |
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| 3. |
- Cossarizza, A., et al.
(författare)
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Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
- 2019
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Ingår i: European Journal of Immunology. - : Wiley. - 0014-2980 .- 1521-4141. ; 49:10, s. 1457-1973
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Tidskriftsartikel (refereegranskat)abstract
- These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry enabling immunologists to avoid the common errors that often undermine immunological data. Notably, there are comprehensive sections of all major immune cell types with helpful Tables detailing phenotypes in murine and human cells. The latest flow cytometry techniques and applications are also described, featuring examples of the data that can be generated and, importantly, how the data can be analysed. Furthermore, there are sections detailing tips, tricks and pitfalls to avoid, all written and peer-reviewed by leading experts in the field, making this an essential research companion.
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| 4. |
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| 5. |
- Kuschmierz, Paul, et al.
(författare)
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European first-year university students accept evolution but lack substantial knowledge about it : A standardized European cross-country assessment
- 2021
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Ingår i: Evolution. - : BioMed Central (BMC). - 1936-6426 .- 1936-6434. ; 14:1, s. 1-22
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Tidskriftsartikel (refereegranskat)abstract
- Background: Investigations of evolution knowledge and acceptance and their relation are central to evolution education research. Ambiguous results in this field of study demonstrate a variety of measuring issues, for instance differently theorized constructs, or a lack of standardized methods, especially for cross-country comparisons. In particular, meaningful comparisons across European countries, with their varying cultural backgrounds and education systems, are rare, often include only few countries, and lack standardization. To address these deficits, we conducted a standardized European survey, on 9200 first-year university students in 26 European countries utilizing a validated, comprehensive questionnaire, the “Evolution Education Questionnaire”, to assess evolution acceptance and knowledge, as well as influencing factors on evolution acceptance. Results: We found that, despite European countries’ different cultural backgrounds and education systems, European first-year university students generally accept evolution. At the same time, they lack substantial knowledge about it, even if they are enrolled in a biology-related study program. Additionally, we developed a multilevel-model that determines religious faith as the main influencing factor in accepting evolution. According to our model, knowledge about evolution and interest in biological topics also increase acceptance of evolution, but to a much lesser extent than religious faith. The effect of age and sex, as well as the country’s affiliation, students’ denomination, and whether or not a student is enrolled in a biology-related university program, is negligible. Conclusions: Our findings indicate that, despite all their differences, most of the European education systems for upper secondary education lead to acceptance of evolution at least in university students. It appears that, at least in this sample, the differences in knowledge between countries reflect neither the extent to which school curricula cover evolutionary biology nor the percentage of biology-related students in the country samples. Future studies should investigate the role of different European school curricula, identify particularly problematic or underrepresented evolutionary concepts in biology education, and analyze the role of religious faith when teaching evolution.
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| 6. |
- Cvetkovic, Vladimir, et al.
(författare)
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Transport and retention from single to multiple fractures in crystalline rock at Aspo (Sweden) : 1. Evaluation of tracer test results and sensitivity analysis
- 2010
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Ingår i: Water resources research. - 0043-1397 .- 1944-7973. ; 46, s. W05505-
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Tidskriftsartikel (refereegranskat)abstract
- We evaluate the breakthrough curves obtained within a comprehensive experimental program for investigating the retention properties of crystalline rock, referred to as Tracer Retention Understanding Experiments (TRUE). The tracer tests were conducted at the Aspo Hard Rock Laboratory (Sweden) in two phases jointly referred to as TRUE Block Scale (TBS); the TBS tests comprise a total of 17 breakthrough curves with nonsorbing and a range of sorbing tracers. The Euclidian length scales are between 10 and 30 m, compared to 5 m for the earlier tests TRUE-1. The unlimited diffusion model is consistent with measured breakthrough curves and is adopted here for evaluation. The model has four independent parameters, two of which are related to advection and dispersion, one which is related to diffusion-sorption, and one which is related to surface sorption; the individual retention parameters or properties cannot be inferred from breakthrough curves alone and require additional constraints. The mean water residence times for the TBS tests are in the range 15-250 h, whereas the coefficient of variation of the water residence times is in the range 0.4-0.6. A consistent trend is found in the calibrated retention parameters with the sorption affinities of the tracers involved. Using Bode sensitivity functions, it is shown that sensitivity increases for the retention parameter with increasing sorption affinity; for nonsorbing tracers, diffusion and hydrodynamic dispersion are shown to "compete," exhibiting similar effects; hence, their estimates are uncertain. The analysis presented here exposes a few fundamental limitations and sensitivities when evaluating diffusion-controlled retention in the subsurface; it is general and applicable to any site with comparable tracer test data. In part 2, it will be shown how discrete fracture network simulations based on the hydrostructural information available can be used for further constraining individual retention parameters, in particular, the active specific surface area (s(f)) and the rock matrix porosity (theta).
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| 7. |
- Didenko, Victor, et al.
(författare)
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Approximate solution of boundary integral equations for biharmonic problems in non-smooth domains
- 2013
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Ingår i: Proceedings in Applied Mathematics and Mechanics. - : Wiley. - 1617-7061. ; 13:1, s. 435-438
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Konferensbidrag (refereegranskat)abstract
- This paper deals with approximate solutions to integral equations arising in boundary value problems for the biharmonic equation in simply connected piecewise smooth domains. The approximation method considered demonstrates excellent convergence even in the case of boundary conditions discontinuous at corner points. In an application we obtain very accurate approximations for some characteristics of two-dimensional Stokes flow in non-smooth domains.
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| 8. |
- Painter, S. L., et al.
(författare)
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Effect of kinetic limitations on colloid-facilitated radionuclide transport at the field scale
- 2006
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Ingår i: Proceedings of the 11th International High Level Radioactive Waste Management Conference, IHLRWM. - 0894486918 - 9780894486913 ; , s. 323-329
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Konferensbidrag (refereegranskat)abstract
- Sorption onto natural groundwater colloids, a process that may enhance field-scale transport of radionuclides in the subsurface, is typically modeled in studies of potential high-level waste repositories using equilibrium partitioning assumptions. A new streamline-based model suggests that kinetic limitations on radionuclide sorption/desoption may significantly enhance field-scale radionuclide transport in some situations. Specifically, the leading edge of mass breakthrough curves may be enhanced if the kinetic rate constants are in a critical range as quantified by a Damkohler-type number. Application of the model to plutonium transport in the alluvial aquifer near Yucca Mountain, Nevada indicates that the bulk of the uncertain parameter space is in the equilibrium range. However, a small parameter region is in the kinetic regime. Monte Carlo simulations suggest that this kinetic region of the parameter space may cause early breakthrough for a small fraction of migrating plutonium, but the effect on peak breakthrough is minimal.
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| 9. |
- Painter, S. L., et al.
(författare)
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Time-domain random walk algorithms for simulating radionuclide transport in fractured porous rock
- 2006
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Ingår i: Proceedings of the 11th International High Level Radioactive Waste Management Conference. - 0894486918 - 9780894486913 ; , s. 293-300
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Konferensbidrag (refereegranskat)abstract
- Time-domain random walk (TDRW) algorithms are efficient methods for simulating solute transport along one-dimensional pathways. New extensions of the TDRW algorithm accommodate decay and in-growth of radionuclides in a decay chain and time-dependent transport velocities. Validation tests using equilibrium sorption and matrix diffusion retention models demonstrate that the extended TDRW algorithm is accurate and computationally efficient. When combined with stochastic simulation of transport properties, the resulting algorithm, Particle On Random Streamline Segment (PORSS), also captures the effects of random spatial variations in transport velocities, including the effects of very broad velocity distributions. When used in combination with discrete fracture network simulations, the PORSS algorithm provides an accurate and practical method for simulating radionuclide transport at the geosphere scale without invoking the advection-dispersion equation.
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| 10. |
- Painter, Scott L., et al.
(författare)
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Time-domain random-walk algorithms for simulating radionuclide transport in fractured porous rock
- 2008
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Ingår i: Nuclear Technology. - 0029-5450 .- 1943-7471. ; 163:1, s. 129-136
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Tidskriftsartikel (refereegranskat)abstract
- Time-domain random-walk (TDRW) algorithms are efficient methods for simulating solute transport along one-dimensional pathways. New extensions of the TDRW algorithm accommodate decay and ingrowth of radionuclides in a decay chain and time-dependent transport velocities. Tests using equilibrium sorption and matrix diffusion retention models demonstrate that the extended TDRW algorithm is accurate and computationally efficient. When combined with stochastic simulation of transport properties, the resulting algorithm, Particle on Random Streamline Segment (PORSS), also captures the effects of random spatial variations in transport velocities, including the effects of very broad velocity distributions. When used in combination with discrete fracture network simulations, the PORSS algorithm provides an accurate and practical method for simulating radionuclide transport at the geosphere scale without invoking the advection-dispersion equation.
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