| 1. |
|
|
| 2. |
- Tabiri, S, et al.
(författare)
-
- 2021
-
swepub:Mat__t
|
|
| 3. |
- Moser, O., et al.
(författare)
-
Glucose management for exercise using continuous glucose monitoring (CGM) and intermittently scanned CGM (isCGM) systems in type 1 diabetes: position statement of the European Association for the Study of Diabetes (EASD) and of the International Society for Pediatric and Adolescent Diabetes (ISPAD) endorsed by JDRF and supported by the American Diabetes Association (ADA)
- 2020
-
Ingår i: Diabetologia. - : Springer Science and Business Media LLC. - 0012-186X .- 1432-0428. ; 63, s. 2501-2520
-
Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Physical exercise is an important component in the management of type 1 diabetes across the lifespan. Yet, acute exercise increases the risk of dysglycaemia, and the direction of glycaemic excursions depends, to some extent, on the intensity and duration of the type of exercise. Understandably, fear of hypoglycaemia is one of the strongest barriers to incorporating exercise into daily life. Risk of hypoglycaemia during and after exercise can be lowered when insulin-dose adjustments are made and/or additional carbohydrates are consumed. Glycaemic management during exercise has been made easier with continuous glucose monitoring (CGM) and intermittently scanned continuous glucose monitoring (isCGM) systems; however, because of the complexity of CGM and isCGM systems, both individuals with type 1 diabetes and their healthcare professionals may struggle with the interpretation of given information to maximise the technological potential for effective use around exercise (i.e. before, during and after). This position statement highlights the recent advancements in CGM and isCGM technology, with a focus on the evidence base for their efficacy to sense glucose around exercise and adaptations in the use of these emerging tools, and updates the guidance for exercise in adults, children and adolescents with type 1 diabetes.
|
|
| 4. |
- Yang, B, et al.
(författare)
-
Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve
- 2017
-
Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 8, s. 15481-
-
Tidskriftsartikel (refereegranskat)abstract
- Bicuspid aortic valve (BAV) is a heritable congenital heart defect and an important risk factor for valvulopathy and aortopathy. Here we report a genome-wide association scan of 466 BAV cases and 4,660 age, sex and ethnicity-matched controls with replication in up to 1,326 cases and 8,103 controls. We identify association with a noncoding variant 151 kb from the gene encoding the cardiac-specific transcription factor, GATA4, and near-significance for p.Ser377Gly in GATA4. GATA4 was interrupted by CRISPR-Cas9 in induced pluripotent stem cells from healthy donors. The disruption of GATA4 significantly impaired the transition from endothelial cells into mesenchymal cells, a critical step in heart valve development.
|
|
| 5. |
|
|
| 6. |
- Deeb, Haneen, 1984, et al.
(författare)
-
Changing question format in repeated interviews to detect lies
- 2016
-
Ingår i: Decepticon Conference.
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Lie detection research has typically focused on reports about a single event. However, in many forensic and security contexts, suspects are likely to report on several events, some of them may be untruthful. This presents interviewers with the challenge of detecting which reports are true and which are not. Varying question format in a second interview, we examined differences in liars’ and truth-tellers’ statement inconsistency about two events. One hundred and fifty participants viewed a meeting in which a non-critical and a critical event were discussed. Truth-tellers were instructed to be honest in their reports about both events, whereas liars had to lie about the critical event. In the first interview, all participants provided a free recall account. In a second interview, participants either gave another free recall account or responded to specific questions presented sequentially (concerning one event at a time) or non-sequentially (concerning both events simultaneously). Liars’ accounts featured more repetitions than truth-tellers for both events, particularly in response to questions presented in non-sequential order. The implications for the use of this question format are discussed.
|
|
| 7. |
- Deeb, H., et al.
(författare)
-
Police Officers’ Perceptions of Statement Inconsistency
- 2018
-
Ingår i: Criminal justice and behavior. - : SAGE Publications. - 0093-8548 .- 1552-3594. ; 45:5, s. 644-665
-
Tidskriftsartikel (refereegranskat)abstract
- We examined police officers’ (N = 71) perceptions of statement inconsistency types (within-statement, between-statement, statement-evidence, and within-group inconsistencies). Approximately half of the officers reported looking for statement inconsistency to detect deception. Officers generally associated contradictions and omissions with deception, and repetitions and reminiscences with truthfulness, but they were most likely to use contradictions. Officers reported using statement-evidence inconsistency more than any other inconsistency type, and they believed it was the easiest type to assess. Younger officers tended to believe that liars attempt to eliminate within-statement inconsistency unless they are strategically presented with incriminating evidence. Moreover, the majority of officers indicated that they have used drawings to assess inconsistencies with suspects’ verbal statements. Finally, suspects’ criminal history, intelligence, and personality were believed to influence statement (in)consistency. These findings are discussed in light of the literature on statement inconsistency, and recommendations regarding the applied use of statement inconsistency types are offered.
|
|
| 8. |
- Deeb, Haneen, 1984, et al.
(författare)
-
Suspects' consistency in statements concerning two events when different question formats are used
- 2017
-
Ingår i: Journal of Investigative Psychology and Offender Profiling. - : Wiley. - 1544-4759. ; 14:1, s. 74-87
-
Tidskriftsartikel (refereegranskat)abstract
- Lie detection research has typically focused on reports about a single event. However, in many forensic and security contexts, suspects are likely to report on several events, some of them may be untruthful. This presents interviewers with the challenge of detecting which reports are true and which are not. Varying question format in a second interview, we examined differences in liars' and truth‐tellers' statement consistency about two events. One hundred and fifty participants viewed a meeting in which a noncritical and a critical event were discussed. Truth‐tellers were instructed to be honest in their reports about both events, whereas liars had to lie about the critical event. In the first interview, all participants provided a free recall account. In a second interview, participants either gave another free recall account or responded to specific questions presented sequentially (concerning one event at a time) or nonsequentially (concerning both events simultaneously). Liars' accounts featured fewer repetitions than truth‐tellers for both events, particularly in response to questions presented in nonsequential order. The implications for the use of this question format are discussed.
|
|
| 9. |
|
|
| 10. |
- Hokken-Koelega, A. C. S., et al.
(författare)
-
International Consensus Guideline on Small for Gestational Age: Etiology and Management From Infancy to Early Adulthood
- 2023
-
Ingår i: Endocrine Reviews. - : The Endocrine Society. - 0163-769X .- 1945-7189. ; 44:3, s. 539-565
-
Tidskriftsartikel (refereegranskat)abstract
- This International Consensus Guideline was developed by experts in the field of small for gestational age (SGA) of 10 pediatric endocrine societies worldwide. A consensus meeting was held and 1300 articles formed the basis for discussions. All experts voted about the strengths of the recommendations. The guideline gives new and clinically relevant insights into the etiology of short stature after SGA birth, including novel knowledge about (epi)genetic causes. Further, it presents long-term consequences of SGA birth and also reviews new treatment options, including treatment with gonadotropin-releasing hormone agonist (GnRHa) in addition to growth hormone (GH) treatment, as well as the metabolic and cardiovascular health of young adults born SGA after cessation of childhood GH treatment in comparison with appropriate control groups. To diagnose SGA, accurate anthropometry and use of national growth charts are recommended. Follow-up in early life is warranted and neurodevelopment evaluation in those at risk. Excessive postnatal weight gain should be avoided, as this is associated with an unfavorable cardiometabolic health profile in adulthood. Children born SGA with persistent short stature < -2.5 SDS at age 2 years or < -2 SDS at 3 to 4 years of age, should be referred for diagnostic workup. In case of dysmorphic features, major malformations, microcephaly, developmental delay, intellectual disability, and/or signs of skeletal dysplasia, genetic testing should be considered. Treatment with 0.033 to 0.067 mg GH/kg/day is recommended in case of persistent short stature at age of 3 to 4 years. Adding GnRHa treatment could be considered when short adult height is expected at pubertal onset. All young adults born SGA require counseling to adopt a healthy lifestyle.
|
|
